Investigated event: Influence on apoptotic protein activity in presence of LPS
Name | Value |
---|---|
Compound | Andrographolide |
Investigated event | Influence on apoptotic protein activity in presence of LPS |
Experiment type | Western Blot |
Concentration | 10.00 µM |
Cell line | RAW264.7 |
Organism | Homo sapiens |
Animal model | |
STAT protein | |
Other | Bcl-xL |
Reference
Andrographolide acts as an anti-inflammatory agent in LPS-stimulated RAW264.7 macrophages by inhibiting STAT3-mediated suppression of the NF-κB pathway. Journal of ethnopharmacology Ko-Chen Lee, Hen-Hong Chang, Ying-Hui Chung, Tzung-Yan Lee, 135, 3, 2011-06-01, 2011-04-08, 10.1016/j.jep.2011.03.068
DOI: 10.1016/j.jep.2011.03.068
PUBMED:
21497192
PMCID: 21497192