Investigated event: Influence on apoptotic protein activity in presence of LPS

Name Value
Compound Andrographolide
Investigated event Influence on apoptotic protein activity in presence of LPS
Experiment type Western Blot
Concentration 10.00 µM
Cell line RAW264.7
Organism Homo sapiens
Animal model
STAT protein
Other Bcl-xL
Reference
Andrographolide acts as an anti-inflammatory agent in LPS-stimulated RAW264.7 macrophages by inhibiting STAT3-mediated suppression of the NF-κB pathway. Journal of ethnopharmacology Ko-Chen Lee, Hen-Hong Chang, Ying-Hui Chung, Tzung-Yan Lee, 135, 3, 2011-06-01, 2011-04-08, 10.1016/j.jep.2011.03.068 DOI: 10.1016/j.jep.2011.03.068 PUBMED: 21497192 PMCID: 21497192