Investigated event: Influence on cell viability in presence of LPS

Name Value
Compound Andrographolide
Investigated event Influence on cell viability in presence of LPS
Experiment type MTT Assay
Concentration 50.00 µM
Cell line RAW264.7
Organism Homo sapiens
Animal model
STAT protein
Other
Reference
Andrographolide acts as an anti-inflammatory agent in LPS-stimulated RAW264.7 macrophages by inhibiting STAT3-mediated suppression of the NF-κB pathway. Journal of ethnopharmacology Ko-Chen Lee, Hen-Hong Chang, Ying-Hui Chung, Tzung-Yan Lee, 135, 3, 2011-06-01, 2011-04-08, 10.1016/j.jep.2011.03.068 DOI: 10.1016/j.jep.2011.03.068 PUBMED: 21497192 PMCID: 21497192