Investigated event: Influence on cell proliferation in tumor tissue in presence of gemcitabine
| Name | Value |
|---|---|
| Compound | Andrographolide |
| Investigated event | Influence on cell proliferation in tumor tissue in presence of gemcitabine |
| Experiment type | TUNEL |
| Concentration | 15.00 mg/kg |
| Cell line | AsPC-1 (xenograft) |
| Organism | Mus musculus |
| Animal model | BALB/c |
| STAT protein | |
| Other |
Reference
Andrographolide causes apoptosis via inactivation of STAT3 and Akt and potentiates antitumor activity of gemcitabine in pancreatic cancer. Toxicology letters Guo-Qing Bao, Bai-Yong Shen, Chun-Peng Pan, Ya-Jing Zhang, Min-Min Shi, Cheng-Hong Peng, 222, 1, 2013-09-12, 2013-07-08, 10.1016/j.toxlet.2013.06.241
DOI: 10.1016/j.toxlet.2013.06.241
PUBMED: 23845849
PMCID: 23845849