Investigated event: Influence on apoptotic and cell cycle protein activity in presence of gemcitabine

Name Value
Compound Andrographolide
Investigated event Influence on apoptotic and cell cycle protein activity in presence of gemcitabine
Experiment type Western Blot
Concentration 10.00 µM
Cell line AsPC-1
Organism Homo sapiens
Animal model
STAT protein
Other Cyclin D1
Reference
Andrographolide causes apoptosis via inactivation of STAT3 and Akt and potentiates antitumor activity of gemcitabine in pancreatic cancer. Toxicology letters Guo-Qing Bao, Bai-Yong Shen, Chun-Peng Pan, Ya-Jing Zhang, Min-Min Shi, Cheng-Hong Peng, 222, 1, 2013-09-12, 2013-07-08, 10.1016/j.toxlet.2013.06.241 DOI: 10.1016/j.toxlet.2013.06.241 PUBMED: 23845849 PMCID: 23845849