Investigated event: Influence on apoptotic and cell cycle protein activity
| Name | Value |
|---|---|
| Compound | Andrographolide |
| Investigated event | Influence on apoptotic and cell cycle protein activity |
| Experiment type | Western Blot |
| Concentration | 25.00 µM |
| Cell line | Panc-1 |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | |
| Other | Cytochrome C (mitochondria) |
Reference
Andrographolide causes apoptosis via inactivation of STAT3 and Akt and potentiates antitumor activity of gemcitabine in pancreatic cancer. Toxicology letters Guo-Qing Bao, Bai-Yong Shen, Chun-Peng Pan, Ya-Jing Zhang, Min-Min Shi, Cheng-Hong Peng, 222, 1, 2013-09-12, 2013-07-08, 10.1016/j.toxlet.2013.06.241
DOI: 10.1016/j.toxlet.2013.06.241
PUBMED: 23845849
PMCID: 23845849