Investigated event: Influence on apoptotic and cell cycle protein activity

Name Value
Compound Andrographolide
Investigated event Influence on apoptotic and cell cycle protein activity
Experiment type Western Blot
Concentration 25.00 µM
Cell line Panc-1
Organism Homo sapiens
Animal model
STAT protein
Other Survivin
Reference
Andrographolide causes apoptosis via inactivation of STAT3 and Akt and potentiates antitumor activity of gemcitabine in pancreatic cancer. Toxicology letters Guo-Qing Bao, Bai-Yong Shen, Chun-Peng Pan, Ya-Jing Zhang, Min-Min Shi, Cheng-Hong Peng, 222, 1, 2013-09-12, 2013-07-08, 10.1016/j.toxlet.2013.06.241 DOI: 10.1016/j.toxlet.2013.06.241 PUBMED: 23845849 PMCID: 23845849