Investigated event: Influence on protein activity in presence of IL-6

Name Value
Compound AZD1480
Investigated event Influence on protein activity in presence of IL-6
Experiment type Western Blot
Concentration 2.50 µM
Cell line KCNR
Organism Homo sapiens
Animal model
STAT protein
Other p-JAK2 (Y1007/10080
Reference
Inhibition of STAT3 with orally active JAK inhibitor, AZD1480, decreases tumor growth in Neuroblastoma and Pediatric Sarcomas In vitro and In vivo. Oncotarget Shuang Yan, Zhijie Li, Carol J Thiele, 4, 3, None, None, 10.18632/oncotarget.930 DOI: 10.18632/oncotarget.930 PUBMED: 23531921 PMCID: PMC3717306