Investigated event: Influence on protein activity in tumor tissue in presence of cisplatin
| Name | Value |
|---|---|
| Compound | 3,3 diindolylmethane |
| Investigated event | Influence on protein activity in tumor tissue in presence of cisplatin |
| Experiment type | Western Blot |
| Concentration | 3.00 mg/kg |
| Cell line | SKOV-3 (xenograft) |
| Organism | Mus musculus |
| Animal model | athymic nude mice |
| STAT protein | |
| Other | Cleaved PARP |
Reference
Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3). BMC medicine Prabodh K Kandala, Sanjay K Srivastava, 10, None, 2012-01-26, 2012-01-26, 10.1186/1741-7015-10-9.
DOI: 10.1186/1741-7015-10-9.
PUBMED: 22280969
PMCID: PMC3298725