Investigated event: Influence on protein activity ex vivo
Name | Value |
---|---|
Compound | Ly5 |
Investigated event | Influence on protein activity ex vivo |
Experiment type | Western Blot |
Concentration | 10.00 µM |
Cell line | MG63.3 |
Organism | Mus musculus |
Animal model | |
STAT protein | p-STAT3 |
Other |
Reference
Target specificity, in vivo pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma. PloS one Peter Y Yu, Heather L Gardner, Ryan Roberts, Hakan Cam, Seethalakshmi Hariharan, Ling Ren, Amy K LeBlanc, Hui Xiao, Jiayuh Lin, Denis C Guttridge, Xiaokui Mo, Chad E Bennett, Christopher C Coss, Yonghua Ling, Mitch A Phelps, Peter Houghton, Cheryl A London, 12, 7, None, 2017-07-27, 10.1371/journal.pone.0181885
DOI: 10.1371/journal.pone.0181885
PUBMED:
28750090
PMCID: PMC5531494