Investigated event: Influence on protein activity

Name Value
Compound Ly5
Investigated event Influence on protein activity
Experiment type Western Blot
Concentration 1.00 µM
Cell line Rh30
Organism Homo sapiens
Animal model
STAT protein p-STAT3
Other
Reference
Target specificity, in vivo pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma. PloS one Peter Y Yu, Heather L Gardner, Ryan Roberts, Hakan Cam, Seethalakshmi Hariharan, Ling Ren, Amy K LeBlanc, Hui Xiao, Jiayuh Lin, Denis C Guttridge, Xiaokui Mo, Chad E Bennett, Christopher C Coss, Yonghua Ling, Mitch A Phelps, Peter Houghton, Cheryl A London, 12, 7, None, 2017-07-27, 10.1371/journal.pone.0181885 DOI: 10.1371/journal.pone.0181885 PUBMED: 28750090 PMCID: PMC5531494