Investigated event: Influence on protein activity in presence of IL-6
| Name | Value |
|---|---|
| Compound | OPB-31121 |
| Investigated event | Influence on protein activity in presence of IL-6 |
| Experiment type | Western Blot |
| Concentration | 1.00 nM |
| Cell line | SNU668 |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | p-STAT3 (S727) |
| Other |
Reference
OPB-31121, a novel small molecular inhibitor, disrupts the JAK2/STAT3 pathway and exhibits an antitumor activity in gastric cancer cells. Cancer letters Mi-Jung Kim, Hyun-Jin Nam, Hwang-Phill Kim, Sae-Won Han, Seock-Ah Im, Tae-You Kim, Do-Youn Oh, Yung-Jue Bang, 335, 1, 2013-07-10, 2013-02-10, 10.1016/j.canlet.2013.02.010
DOI: 10.1016/j.canlet.2013.02.010
PUBMED: 23402820
PMCID: 23402820