Investigated event: Influence on cell proliferation

Name Value
Compound OPB-31121
Investigated event Influence on cell proliferation
Experiment type Colony formation assay
Concentration 50.00 nM
Cell line DU145
Organism Homo sapiens
Animal model
STAT protein
Other
Reference
Hitting the right spot: Mechanism of action of OPB-31121, a novel and potent inhibitor of the Signal Transducer and Activator of Transcription 3 (STAT3). Molecular oncology Lara Brambilla, Davide Genini, Erik Laurini, Jessica Merulla, Laurent Perez, Maurizio Fermeglia, Giuseppina M Carbone, Sabrina Pricl, Carlo V Catapano, 9, 6, None, 2015-03-05, 10.1016/j.molonc.2015.02.012 DOI: 10.1016/j.molonc.2015.02.012 PUBMED: 25777967 PMCID: PMC5528765