Investigated event: Infleunce on protein activity in presence of IL-6
| Name | Value |
|---|---|
| Compound | OPB-31121 |
| Investigated event | Infleunce on protein activity in presence of IL-6 |
| Experiment type | Western Blot |
| Concentration | 50.00 nM |
| Cell line | LNCaP |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | p-STAT3 (Y705) |
| Other |
Reference
Hitting the right spot: Mechanism of action of OPB-31121, a novel and potent inhibitor of the Signal Transducer and Activator of Transcription 3 (STAT3). Molecular oncology Lara Brambilla, Davide Genini, Erik Laurini, Jessica Merulla, Laurent Perez, Maurizio Fermeglia, Giuseppina M Carbone, Sabrina Pricl, Carlo V Catapano, 9, 6, None, 2015-03-05, 10.1016/j.molonc.2015.02.012
DOI: 10.1016/j.molonc.2015.02.012
PUBMED: 25777967
PMCID: PMC5528765