Investigated event: Influence on cell apoptosis
| Name | Value |
|---|---|
| Compound | AZD1480 |
| Investigated event | Influence on cell apoptosis |
| Experiment type | Caspase 3/7 activity |
| Concentration | 1.00 µM |
| Cell line | KCNR |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | |
| Other |
Reference
Inhibition of STAT3 with orally active JAK inhibitor, AZD1480, decreases tumor growth in Neuroblastoma and Pediatric Sarcomas In vitro and In vivo. Oncotarget Shuang Yan, Zhijie Li, Carol J Thiele, 4, 3, None, None, 10.18632/oncotarget.930
DOI: 10.18632/oncotarget.930
PUBMED: 23531921
PMCID: PMC3717306