Investigated event: Influence on expression of proteins downstream target genes

Name Value
Compound XZH-5
Investigated event Influence on expression of proteins downstream target genes
Experiment type RT-PCR
Concentration 50.00 µM
Cell line MDA-MB-231
Organism Homo sapiens
Animal model
STAT protein
Other Survivin
Reference
XZH-5 inhibits STAT3 phosphorylation and enhances the cytotoxicity of chemotherapeutic drugs in human breast and pancreatic cancer cells. PloS one Aiguo Liu, Yan Liu, Zhigang Jin, Qun Hu, Li Lin, David Jou, Jing Yang, Zhenghu Xu, Hong Wang, Chenglong Li, Jiayuh Lin, 7, 10, None, 2012-10-03, 10.1371/journal.pone.0046624 DOI: 10.1371/journal.pone.0046624 PUBMED: 23056374 PMCID: PMC3463519