Investigated event: Influence on protein-DNA interaction in presence of EGF
| Name | Value |
|---|---|
| Compound | Withacnistin |
| Investigated event | Influence on protein-DNA interaction in presence of EGF |
| Experiment type | Immunofluorescence |
| Concentration | 3.00 µM |
| Cell line | MDA-MB-468 |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | p-STAT3 |
| Other |
Reference
Withacnistin inhibits recruitment of STAT3 and STAT5 to growth factor and cytokine receptors and induces regression of breast tumours. British journal of cancer X Zhang, M A Blaskovich, K D Forinash, S M Sebti, 111, 5, 2014-08-26, 2014-07-01, 10.1038/bjc.2014.349
DOI: 10.1038/bjc.2014.349
PUBMED: 24983364
PMCID: PMC4150266