Investigated event: Influence on protein activity in transfected cells in presence of EGF
| Name | Value |
|---|---|
| Compound | Tocotrienol |
| Investigated event | Influence on protein activity in transfected cells in presence of EGF |
| Experiment type | Luciferase activity |
| Concentration | 50.00 µM |
| Cell line | PLC/PRF/5 |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | STAT3 |
| Other |
Reference
γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent. British journal of pharmacology Peramaiyan Rajendran, Feng Li, Kanjoormana Aryan Manu, Muthu K Shanmugam, Ser Yue Loo, Alan Prem Kumar, Gautam Sethi, 163, 2, None, None, 10.1111/j.1476-5381.2010.01187
DOI: 10.1111/j.1476-5381.2010.01187
PUBMED: 21198544
PMCID: PMC3087132