Investigated event: Influence on dowstream target genes expression in tumor tissue

Name Value
Compound STX-0119
Investigated event Influence on dowstream target genes expression in tumor tissue
Experiment type Western Blot
Concentration 80.00 mg/kg
Cell line SCC3 (xenograft)
Organism Mus musculus
Animal model BALB/cA-nu/nu
STAT protein
Other Cleaved Caspase-3
Reference
Antitumor activity of a novel small molecule STAT3 inhibitor against a human lymphoma cell line with high STAT3 activation. International journal of oncology Tadashi Ashizawa, Haruo Miyata, Hidee Ishii, Chie Oshita, Kenji Matsuno, Yoshiaki Masuda, Toshio Furuya, Tadashi Okawara, Masami Otsuka, Naohisa Ogo, Akira Asai, Yasuto Akiyama, 38, 5, None, 2011-02-28, 10.3892/ijo.2011.957 DOI: 10.3892/ijo.2011.957 PUBMED: 21369699 PMCID: 21369699