Investigated event: Influence on protein activity in presence of TNF-α
Name | Value |
---|---|
Compound | Auranofin |
Investigated event | Influence on protein activity in presence of TNF-α |
Experiment type | Western Blot |
Concentration | 0.05 µM |
Cell line | U266 |
Organism | Homo sapiens |
Animal model | |
STAT protein | |
Other | p-IκBα |
Reference
The gold compound auranofin induces apoptosis of human multiple myeloma cells through both down-regulation of STAT3 and inhibition of NF-κB activity. Leukemia research Aya Nakaya, Morihiko Sagawa, Akihiro Muto, Hideo Uchida, Yasuo Ikeda, Masahiro Kizaki, 35, 2, None, 2010-06-12, 10.1016/j.leukres.2010.05.011
DOI: 10.1016/j.leukres.2010.05.011
PUBMED:
20542334
PMCID: 20542334