Investigated event: Influence on protein activity in presence of TNF-α

Name Value
Compound Auranofin
Investigated event Influence on protein activity in presence of TNF-α
Experiment type Western Blot
Concentration 0.05 µM
Cell line U266
Organism Homo sapiens
Animal model
STAT protein
Other p-IκBα
Reference
The gold compound auranofin induces apoptosis of human multiple myeloma cells through both down-regulation of STAT3 and inhibition of NF-κB activity. Leukemia research Aya Nakaya, Morihiko Sagawa, Akihiro Muto, Hideo Uchida, Yasuo Ikeda, Masahiro Kizaki, 35, 2, None, 2010-06-12, 10.1016/j.leukres.2010.05.011 DOI: 10.1016/j.leukres.2010.05.011 PUBMED: 20542334 PMCID: 20542334