Investigated event: Influence on apoptosis-associated proteins in presence of IL-6
| Name | Value |
|---|---|
| Compound | Auranofin |
| Investigated event | Influence on apoptosis-associated proteins in presence of IL-6 |
| Experiment type | Western Blot |
| Concentration | 0.05 µM |
| Cell line | U266 |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | |
| Other | Bcl-2 |
Reference
The gold compound auranofin induces apoptosis of human multiple myeloma cells through both down-regulation of STAT3 and inhibition of NF-κB activity. Leukemia research Aya Nakaya, Morihiko Sagawa, Akihiro Muto, Hideo Uchida, Yasuo Ikeda, Masahiro Kizaki, 35, 2, None, 2010-06-12, 10.1016/j.leukres.2010.05.011
DOI: 10.1016/j.leukres.2010.05.011
PUBMED: 20542334
PMCID: 20542334