Investigated event: Influence on caspase activation

Name Value
Compound Auranofin
Investigated event Influence on caspase activation
Experiment type Western Blot
Concentration 0.05 µM
Cell line U266
Organism Homo sapiens
Animal model
STAT protein
Other Pro-caspase 3
Reference
The gold compound auranofin induces apoptosis of human multiple myeloma cells through both down-regulation of STAT3 and inhibition of NF-κB activity. Leukemia research Aya Nakaya, Morihiko Sagawa, Akihiro Muto, Hideo Uchida, Yasuo Ikeda, Masahiro Kizaki, 35, 2, None, 2010-06-12, 10.1016/j.leukres.2010.05.011 DOI: 10.1016/j.leukres.2010.05.011 PUBMED: 20542334 PMCID: 20542334