Investigated event: Influence on protein activity in presence of IL-11
| Name | Value |
|---|---|
| Compound | Ponatinib |
| Investigated event | Influence on protein activity in presence of IL-11 |
| Experiment type | Western Blot |
| Concentration | 1.00 µM |
| Cell line | DLD-1 |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | |
| Other | JAK2 |
Reference
Ponatinib Inhibits Multiple Signaling Pathways Involved in STAT3 Signaling and Attenuates Colorectal Tumor Growth. Cancers Fiona H Tan, Tracy L Putoczki, Jieqiong Lou, Elizabeth Hinde, Frédéric Hollande, Julie Giraud, Stanley S Stylli, Lucia Paradiso, Hong-Jian Zhu, Oliver M Sieber, Rodney B Luwor, 10, 12, 2018-12-19, 2018-12-19, 10.3390/cancers10120526
DOI: 10.3390/cancers10120526
PUBMED: 30572654
PMCID: PMC6316865