Investigated event: Influence on protein activity in presence of IL-11

Name Value
Compound Ponatinib
Investigated event Influence on protein activity in presence of IL-11
Experiment type Western Blot
Concentration 0.10 µM
Cell line DIFI
Organism Homo sapiens
Animal model
STAT protein
Other GAPDH
Reference
Ponatinib Inhibits Multiple Signaling Pathways Involved in STAT3 Signaling and Attenuates Colorectal Tumor Growth. Cancers Fiona H Tan, Tracy L Putoczki, Jieqiong Lou, Elizabeth Hinde, Frédéric Hollande, Julie Giraud, Stanley S Stylli, Lucia Paradiso, Hong-Jian Zhu, Oliver M Sieber, Rodney B Luwor, 10, 12, 2018-12-19, 2018-12-19, 10.3390/cancers10120526 DOI: 10.3390/cancers10120526 PUBMED: 30572654 PMCID: PMC6316865