YM-341619

Name Value
Weight 0.000 N/A
Zinc ID N/A
Smiles N/A
Molecular formula N/A
Mode of inhibition STAT and IL-4; Non-peptide small molecule
CAS 643082-52-4

Clinical Trials

Study title Status Conditions Link

References

Publication DOI Pubmed PMCID
Identification of 4-benzylamino-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5-carboxamide derivatives as potent and orally bioavailable STAT6 inhibitors. Bioorganic & medicinal chemistry Shinya Nagashima, Hiroshi Nagata, Masahiro Iwata, Masaki Yokota, Hiroyuki Moritomo, Masaya Orita, Sadao Kuromitsu, Akiko Koakutsu, Keiko Ohga, Makoto Takeuchi, Mitsuaki Ohta, Shin-ichi Tsukamoto, 16, 13, 2008-07-01, 2008-05-17, 10.1016/j.bmc.2008.05.031 10.1016/j.bmc.2008.05.031 18534856 18534856

Filter data

Compound YM-341619
Experiment types ELISA
Concentrations 0.01, 0.10, 1.00, 10.00
Cell lines Spleen T cells
Organisms Mus musculus
Animal models c57BL/6
STAT proteins
Other IFNγ, IL-4

Experiments

Compound Experiment type Investigated event Concentration Cell line Organism Animal model Stat protein Details
YM-341619 ELISA Influence on cytokine production 0.01 µM Spleen T cells Mus musculus c57BL/6
YM-341619 ELISA Influence on cytokine production 0.10 µM Spleen T cells Mus musculus c57BL/6
YM-341619 ELISA Influence on cytokine production 1.00 µM Spleen T cells Mus musculus c57BL/6
YM-341619 ELISA Influence on cytokine production 10.00 µM Spleen T cells Mus musculus c57BL/6
YM-341619 ELISA Influence on cytokine production 0.01 µM Spleen T cells Mus musculus c57BL/6
YM-341619 ELISA Influence on cytokine production 0.10 µM Spleen T cells Mus musculus c57BL/6
YM-341619 ELISA Influence on cytokine production 1.00 µM Spleen T cells Mus musculus c57BL/6
YM-341619 ELISA Influence on cytokine production 10.00 µM Spleen T cells Mus musculus c57BL/6