Sorafenib

Name Value
Weight 464.831 g/mol
Zinc ID ZINC1493878
Smiles CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1
Molecular formula C21H16ClF3N4O3
Mode of inhibition Direct JAK2 and STAT; Natural product
CAS 284461-73-0

Clinical Trials

Study title Status Conditions Link
Sorafenib Administered Using a High-dose, Pulsatile Regimen: a Phase I Exposure Escalation Study Completed Neoplasms NCT02636426
Second Line Sorafenib After Pazopanib in Patients With RCC Terminated Metastatic Renal Cell Carcinoma NCT02122003
Sorafenib Concurrent With Yttrium-90 Transarterial Radioembolization in Patients With Advanced Hepatocellular Cancer Withdrawn Hepatocellular Cancer NCT02288507
Phase II Study of Concurrent Sorafenib and Intensity-modulated Radiotherapy (IMRT) for Advanced Hepatocellular Carcinoma Recruiting Hepatocellular Carcinoma, Radiotherapy, Sorafenib NCT03535259
Mechanism of Sorafenib Resistance in Patients With Advanced Hepatocellular Carcinoma Recruiting Hepatocellular Carcinoma NCT02733809
Sorafenib for Patients With Extensive Keloids Terminated Keloids NCT01425216
Sorafenib Treatment in Patients With Hepatocellular Carcinoma With Microvascular Invasion After Radical Resection Terminated Hepatocellular Carcinoma|Recurrence NCT02867280
Sorafenib for Hepatopulmonary Syndrome Terminated Hepatopulmonary Syndrome NCT02021929
Sorafenib Plus Toripalimab for Unresectable HCC With Portal Vein Tumor Thrombus Not yet recruiting Unresectable Hepatocellular Cancer|Portal Vein Tumor Thrombus NCT04069949
Safety and Efficacy of Sorafenib in Patients With Advanced Thyroid Cancer: a Phase II Clinical Study Completed Thyroid Cancer NCT02084732
CVM-1118 and Sorafenib Combination in Subjects With Advanced Hepatocellular Carcinoma Recruiting Hepatocellular Carcinoma|Advanced Cancer NCT03582618
Trial of TRC105 and Sorafenib in Patients With HCC Completed Hepatocellular Carcinoma NCT02560779
Phase â…ˇ Study of HAIC of FOLFOX vs. Sorafenib in HCC Refractory to TACE Terminated Hepatocellular Carcinoma NCT03722498
Sorafenib Chemoembolization Evaluation Controlled Trial Recruiting Hepatocellular Carcinoma NCT01906216
Sorafenib Plus Capecitabine (SorCape) in Previously Treated Metastatic Colorectal Cancer Completed Colorectal Cancer Metastatic NCT01471353
Sorafenib and Cyclophosphamide/Topotecan in Patients With Relapsed and Refractory Neuroblastoma Active, not recruiting Neuroblastoma NCT02298348
Bioequivalence Study of Sorafenib Tablet and Nexavar Completed Fasting NCT02599337
Sorafenib PK in Patients With Advanced HCC and Child-Pugh B Terminated BCLC Stage C HCC|CP-B Liver Cirrhosis NCT04051853
Sorafenib Combined With Transarterial Chemoembolization in Treating HBV-infected Patients With Intermediate Hepatocellular Carcinoma Unknown status PHENYTOIN/SORAFENIB [VA Drug Interaction]|Liver Neoplasms|Carcinoma, Hepatocellular|Digestive System Neoplasms|Neoplasms by Site|Liver Diseases|Adenocarcinoma|Carcinoma|Neoplasms, Glandular and Epithelial|Neoplasms by Histologic Type|DOXORUBICIN/TRASTUZUMAB [VA Drug Interaction]|HBV NCT01556815
Sorafenib Dose Ramp-Up in Hepatocellular Carcinoma (HCC) Completed Hepatocellular Carcinoma NCT01203787
Dose Escalation Study of OMP-54F28 in Combination With Sorafenib in Patients With Hepatocellular Cancer Completed Hepatocellular Cancer|Liver Cancer NCT02069145
Sorafenib for Prophylaxis of Leukemia Relapse in Allo-HSCT Recipients With FLT3-ITD Positive AML Completed Acute Myeloid Leukemia|Hematopoietic Stem Cell Transplantation NCT02474290
Sorafenib for the Treatment of Chronic Lymphocytic Leukemia (CLL) Terminated Chronic Lymphocytic Leukemia NCT01510756
Efficacy and Safety of Concurrent TACE and Sorafenib in Patients With HCC and Extrahepatic Metastasis (COTSOM Study) Unknown status Hepatocellular Carcinoma|Metastasis NCT02311205
Neoadjuvant Sorafenib Therapy Prior to Laser Ablation for Hepatocellular Carcinoma Completed Hepatocellular Carcinoma NCT01507064
Sorafenib and 5-Azacitidine in Acute Leukemia + Myelodysplastic Syndrome Completed Leukemia NCT01254890
A Pilot Study of Sorafenib Examining Biomarkers in Refractory or Relapsed T-Cell Lymphoma Patients Completed T Cell Lymphoma NCT01561833
Phase I/II, Study of Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) + Sorafenib in Acute Myeloid Leukemia Completed Leukemia|Acute Myeloid Leukemia NCT02530476
Evaluate the Efficacy of Sorafenib in Renal Cell Carcinoma Patients After a Radical Resection of the Metastases Unknown status Metastatic Renal Cell Carcinoma NCT01444807
Sorafenib Drug Drug Interaction Study in Healthy Male Subjects Completed Drug Interactions NCT02332031
Sorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade Astrocytomas Terminated neurofibromatosis1 (NF1)|Recurrent or Progressive Optic Pathway Gliomas (OPG)|Recurrent or Progressive Low-grade Glioma NCT01338857
Phase I Trial of Sorafenib + FOLFIRI In Metastatic Colorectal Cancer Completed Metastatic Colorectal Cancer NCT00780169
Transcatheter Arterial Chemoembolization Combined With Sorafenib for Unresectable Hepatocellular Carcinoma Completed Hepatocellular Carcinoma|Face Cancer NCT01833299
Trial of Sorafenib in Hepatocellular Cancer (HCC) Transplant Patients Completed Hepatocellular Cancer NCT00997022
Sorafenib in Elderly Patients With Metastatic Renal Cell Carcinoma Terminated Metastatic Renal Cell Carcinoma NCT01342627
Study to Evaluate the Safety and Efficacy of Sorafenib, in Subject With Refractory Solid Tumors Withdrawn Refractory Solid Tumors NCT02691780
Combination of Sorafenib and Vorinostat in Poor-risk Acute Myelogenous Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS) Completed Leukemia, Myeloid, Acute|Leukemia, Promyelocytic, Acute|Myelodysplastic Syndromes NCT00875745
Efficacy and Safety of Sorafenib in Advanced Renal Cell Carcinoma (RCC) Completed Renal Cell Carcinoma NCT00478114
Y-90 Alone or With Sorafenib for Pre-Transplant Hepatocellular Carcinoma Completed Hepatocellular Carcinoma NCT00846131
Sorafenib Maintenance Therapy for Patients With AML After Allogeneic Stem Cell Transplant Completed Acute Myeloid Leukemia NCT01398501
Correlation Between Sorafenib Plasma Concentrations, Toxicity and Disease Control Rate in Patients Treated by Sorafenib for Hepatocellular Carcinoma Recruiting Hepatocellular Carcinoma (HCC) NCT02834546
Effect of Tumor Treating Fields (TTFields, 150kHz) Concomitant With Sorafenib For Advanced Hepatocellular Carcinoma (HCC) (HEPANOVA) Recruiting Hepatocellular Carcinoma NCT03606590
Transarterial Chemoembolization (TACE) Plus Sorafenib Versus TACE for Advanced Hepatocellular Carcinoma Unknown status Advanced Hepatocellular Carcinoma NCT02150317
A Phase II Trial of OSI-906 and Sorafenib in Advanced Hepatocellular Cancer Terminated Liver Cancer NCT01334710
AZD6244 and Sorafenib in Advanced Hepatocellular Carcinoma Terminated Hepatocellular Carcinoma NCT01029418
Study of Combined Sorafenib With Radiotherapy in Patients With Advanced Hepatocellular Carcinoma Unknown status Hepatocellular Carcinoma NCT01328223
Efficacy and Safety Study of Sorafenib to Treat Advanced Medullary Thyroid Carcinoma Withdrawn Medullary Thyroid Carcinoma NCT01736878
SORAVE - Sorafenib and Everolimus in Solid Tumors Completed Unspecified Adult Solid Tumor, Protocol Specific|Non-Small Cell Lung Cancer NCT00933777
TACE With or Without Sorafenib in Intermediate Stage Hepatocellular Carcinoma Recruiting Hepatocellular Carcinoma NCT02529761
Sorafenib Plus 5-Azacitidine Initial Therapy of Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MS) With FLT3-ITD Mutation Completed Leukemia NCT02196857
YIV-906 (Formerly PHY906/KD018) With Sorafenib in HBV(+) Hepatocellular Carcinoma (HCC) Recruiting Advanced Hepatocellular Carcinoma NCT04000737
Intra-patient Dose Escalation Study of Sorafenib in Advanced Non-small Cell Lung Cancer Completed Carcinoma, Non Small Cell Lung NCT00954278
Preventive Effect of Celecoxib on Sorafenib-related Hand Foot Syndrome, a Single Center, Randomized Controlled Clinical Trail Completed Hepatocellular Carcinoma NCT02961998
Sorafenib in Treating Patients With Locally Advanced or Metastatic Kidney Cancer Terminated Hereditary Clear Cell Renal Cell Carcinoma|Kidney Cancer NCT00727532
Relative Bioavailability of Sorafenib Tablet for Oral Suspension Completed Biological Availability NCT02538393
Study of Low Dose Chemotherapy Plus Sorafenib as Initial Therapy for Patients With Advanced Non-Squamous Cell NSCLC Terminated Non Squamous Cell Lung Cancer|Non Small Cell Lung Cancer NCT00801801
Sorafenib and Radiotherapy in the Treatment of Invasive Bladder Cancer With Conservative Intent Completed Bladder Cancer NCT00544609
Study of Sorafenib, Gemcitabine, and Cisplatin in Advanced Hepatocellular Carcinoma (HCC) Withdrawn Hepatocellular Carcinoma NCT00808145
Evaluating the Combination of Everolimus and Sorafenib in the Treatment of Thyroid Cancer Active, not recruiting Thyroid Cancer NCT01141309
Hepatocellular Carcinoma Study Comparing Vaccinia Virus Based Immunotherapy Plus Sorafenib vs Sorafenib Alone Active, not recruiting Hepatocellular Carcinoma (HCC) NCT02562755
Combination of Sorafenib and Omacetaxine Mepesuccinate in Newly Diagnosed or Relapsed/Refractory AML Carrying FLT3-ITD Recruiting AML|FLT3-ITD Mutation NCT03170895
Sorafenib and TRC105 in Hepatocellular Cancer Completed Hepatoma|Liver Neoplasms|Adenoma, Liver Cell|Carcinoma, Hepatocellular|Liver Neoplasms, Experimental NCT01306058
Perspective Evaluation of Hormones Involved in Serum Phosphate Homeostasis in Patients With Metastatic Renal Cells Carcinoma or Hepatocellular Carcinoma Treated With Sorafenib (SORHORM) Unknown status Kidney Cancer|Liver Cancer NCT01230697
Safety Study of Sorafenib With Androgen Deprivation and Radiotherapy to Treat Prostate Cancer Terminated Prostate Cancer NCT00924807
Sorafenib Induced Autophagy Using Hydroxychloroquine in Hepatocellular Cancer Recruiting Hepatocellular Cancer NCT03037437
Combined Radiotherapy and Sorafenib in Patients With Hepatoma Unknown status Hepatocellular Carcinoma NCT01319942
Phase II Study of Sorafenib + Carboplatin and Docetaxel in First Line Treatment of Stage IIIB/IV NSCLC Completed Non-Small Cell Lung Cancer NCT00647426
Sorafenib in Treating Patients With Advanced Malignant Solid Tumors Completed Unspecified Adult Solid Tumor, Protocol Specific NCT00810394
Pre-operative Administration of Sorafenib in Patients With Metastatic Renal Cell Carcinoma Undergoing Kidney Removal Completed Renal Cell Carcinoma|Metastatic Disease NCT00480389
Safety and Toxicity Study of Sorafenib in Patients With Kidney Cancer Completed Carcinoma, Renal Cell|Kidney Disease|Kidney Cancer NCT00854620
Prospective, Non-interventional, Post-authorization Safety Study That Includes All Patients Diagnosed as Unresectable Differentiated Thyroid Carcinoma and Treated With Sorafenib Recruiting Thyroid Carcinoma NCT02185560
Combination of Temsirolimus and Sorafenib in the Treatment of Radioactive Iodine Refractory Thyroid Cancer Completed Thyroid Cancer NCT01025453
A Study of Radiation With Sorafenib in Advanced Cancer Completed Cancer NCT00610246
Sorafenib Plus Tegafur-uracil (UFT) Versus Sorafenib as First Line Systemic Treatment for Patients With Advanced Stage HCC, Unresectable & Not Eligible for Local Ablation and/or TACE Terminated Advanced Hepatocellular Carcinoma NCT01539018
Sorafenib With BIIB022 in Hepatocellular Carcinoma (HCC) Completed Hepatocellular Carcinoma NCT00956436
Efficacy and Safety of Sorafenib (Nexavar) in Combination With Gemcitabine in Advanced Hepatocellular Carcinoma (HCC) Completed Carcinoma, Hepatocellular NCT00703365
Sorafenib-RT in Treating Hepatocellular Carcinoma (SHEP) Active, not recruiting Hepatocellular Carcinoma NCT00892658
Sorafenib for Patients With Metastatic or Recurrent Esophageal and Gastroesophageal Junction Cancer Completed Esophageal Cancer|Gastroesophageal Junction Cancer NCT00917462
Metformin Plus Sorafenib for Advanced HCC Unknown status Hepatocellular Carcinoma NCT02672488
Sorafenib as Adjuvant to Radioiodine Therapy in Non-Medullary Thyroid Carcinoma Completed Thyroid Cancer NCT00887107
Sorafenib in Treating Patients With Metastatic or Unresectable Kidney Cancer Terminated Kidney Cancer NCT00496756
Sorafenib and Ifosfamide in Treating Patients With High-Grade Soft Tissue Sarcoma or Bone Sarcoma That Can Be Removed by Surgery Terminated Sarcoma NCT00880542
Safety and Efficacy Study of CC-122 Combined With Sorafenib for Primary Liver Cancer Terminated Carcinoma, Hepatocellular NCT02323906
Sorafenib in Combination With RAD001 in Patients With Advanced Neuroendocrine Tumors Completed Neuroendocrine Tumor|Carcinoid Tumor|Pancreatic Neuroendocrine Tumor NCT00942682
A Multi-Center, Non-Controlled Clinical Study of Sorafenib Adjuvant Therapy in Advanced Renal-Cell Carcinoma Unknown status Renal Cell Carcinoma NCT01041482
Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery Active, not recruiting Advanced Adult Hepatocellular Carcinoma|Localized Non-Resectable Adult Hepatocellular Carcinoma|Stage III Childhood Hepatocellular Carcinoma|Stage IIIA Hepatocellular Carcinoma|Stage IIIB Hepatocellular Carcinoma|Stage IIIC Hepatocellular Carcinoma|Stage IV Childhood Hepatocellular Carcinoma|Stage IVA Hepatocellular Carcinoma|Stage IVB Hepatocellular Carcinoma NCT02072486
Stereotactic Radiation Therapy and Sorafenib in the Treatment of Hepatocellular Carcinoma Terminated Hepatocellular Carcinoma|Liver Cancer NCT01005875
Sorafenib Versus Best Supportive Care in Egyptian Hepatocellular Carcinoma Patients. Completed HCC NCT02971696
Sorafenib Therapy Prior to Radiofrequency Ablation for Intermediate Sized Hepatocellular Cancer Unknown status Hepatocellular Cancer NCT00813293
Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable Osteosarcoma Completed Metastatic Osteosarcoma|Relapsed Osteosarcoma NCT01804374
Randomized Phase 1/2 Open-Label Trial of PR104 and Sorafenib in Patients With Advanced Hepatocellular Carcinoma (HCC) Terminated Hepatocellular Carcinoma NCT00862082
Depocyt® With Sorafenib in Neoplastic Meningitis Terminated Neoplastic Meningitis NCT00964743
Study Evaluating Sorafenib Added to Standard Primary Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia Less Than 60 Years of Age Completed Acute Myeloid Leukemia (AML) NCT00893373
Sorafenib in Newly Diagnosed High Grade Glioma Completed Glioblastoma|Gliosarcoma|Anaplastic Astrocytoma|Anaplastic Oligoastrocytoma|Anaplastic Oligodendroglioma NCT00884416
Phase III Sequential Open-label Study to Evaluate the Efficacy and Safety of Sorafenib Followed by Pazopanib Versus Pazopanib Followed by Sorafenib in the Treatment of Advanced / Metastatic Renal Cell Carcinoma (SWITCH-II) Completed Renal Cell Carcinoma NCT01613846
Clinical Study of Sorafenib and Zoledronic Acid to Treat Advanced HCC Unknown status Hepatocellular Carcinoma NCT01259193
Sorafenib and Vorinostat in Treating Patients With Advanced Liver Cancer Completed Liver Cancer NCT01075113
Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable Melanoma Withdrawn Melanoma|Recurrent Melanoma|Stage III Melanoma|Stage IV Melanoma NCT01851408
Sorafenib and Bevacizumab in Combination With Paclitaxel in Patients With Solid Tumors Completed SOLID TUMORS NCT00572078
Combination of Sorafenib and Radiation for Brain Metastases and Primary Brain Tumors Completed Brain Metastases|Primary Brain Tumors NCT00639262
Sorafenib Plus TACE Versus Sorafenib Alone as Postoperative Adjuvant Treatment for Resectable Primary Advanced HCC Recruiting Hepatocellular Carcinoma NCT04143191
TACE Plus Sorafenib Versus TACE Alone for Recurrent Unresectable Hepatocellular Carcinoma Not yet recruiting Hepatocellular Carcinoma|Sorafenib|Transarterial Chemoembolization NCT04103398
Phase 1b/2 Study of Oprozomib in Combination With Sorafenib in Subjects With Advanced Hepatocellular Carcinoma Withdrawn Advanced Hepatocellular Carcinoma NCT02227914
Study of SECOX Versus Sorafenib as First-Line Treatment in Patients With Advanced Hepatocellular Carcinoma (HCC) Active, not recruiting Carcinoma, Hepatocellular|Secondary NCT02716766
Pilot Study of Sorafenib and Bi-weekly Capecitabine in Patients With Advanced Breast and Gastrointestinal Tumors Completed Metastatic Breast Cancer|Gastrointestinal Tumors NCT01640665
Sorafenib vs.TransArterial Chemoembolization Plus RadioTherapy in Hepatocellular Carcinoma With Macrovascular Invasion Completed Hepatocellular Carcinoma NCT01901692
The Treatment of Lapatinib in Combination With Sorafenib in Patients With Advanced Refractory Solid Tumors Completed Solid Tumors NCT00984425
Sorafenib in Treating Non-Smokers or Former Light Smokers With Relapsed or Refractory Stage IIIB or Stage IV Non-Small Cell Lung Cancer Terminated Lung Cancer NCT00754923
Sorafenib With Capecitabine for Patients With Measurable Hepatocellular Carcinoma Terminated Hepatocellular Carcinoma NCT01032850
Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid Tumors Completed Breast Cancer|Colorectal Cancer|Head and Neck Cancer|Lung Cancer|Mesothelioma|Pancreatic Cancer|Prostate Cancer|Sarcoma NCT00703638
Nexavar for Neoadjuvant Treatment of Anaplastic Thyroid Cancer Recruiting Thyroid Cancer, Anaplastic NCT03565536
Study of Combination of Metronomic Oral Vinorelbine and Sorafenib in Patients With Advanced Non-small Cell Lung Cancer Completed Non-Small Cell Lung Cancer NCT00870532
Efficacy and Safety of Bevacizumab Plus Sorafenib for the Third-line Treatment in Metastatic Renal Cancer Patients Unknown status Metastatic Renal Cell Carcinoma NCT02330783
Sorafenib-RT Treatment for Liver Metastasis (SLIM) Active, not recruiting Liver Metastasis|Cancer NCT00892424
Sorafenib in Liver Function Impaired Advanced Hepatocellular Carcinoma Completed Liver Cancer NCT01932385
Sorafenib in Hepatocellular Carcinoma Clinical Practice in Italy Completed Hepatocellular Carcinoma NCT01539681
Oral Hydroxychloroquine Plus Oral Sorafenib to Treat Patients With Refractory or Relapsed Solid Tumors Completed Refractory or Relapsed Solid Tumors NCT01634893
Phase II Trial of Sorafenib (Nexavar) in Patients With Advanced Thyroid Cancer Completed Metastatic Differentiated Thyroid Cancer|Metastatic Poorly Differentiated Thyroid Cancer|Metastatic Anaplastic Thyroid Cancer|Metastatic Medullary Thyroid Cancer NCT00654238
Sorafenib Combined With Chemotherapy for Renal Collecting Duct Carcinoma Completed Renal Cell Carcinoma NCT01762150
Ph. 2 Sorafenib + Protracted Temozolomide in Recurrent GBM Completed Recurrent Glioblastoma Multiforme NCT00597493
Study of Sorafenib Maintenance in Patients With ED-SCLC After Response to Induction Chemotherapy Terminated Small Cell Lung Cancer NCT01159327
A Study of Recombinant Vaccinia Virus Prior to Sorafenib to Treat Unresectable Primary Hepatocellular Carcinoma Completed Carcinoma, Hepatocellular NCT01171651
Study of Everolimus and Sorafenib in Patients With Advanced Thyroid Cancer Who Progressed on Sorafenib Alone Active, not recruiting Differentiated Thyroid Cancer NCT01263951
Sorafenib and Radioembolization With Sir-Spheres® for the Treatment of Metastatic Ocular Melanoma Completed Ocular Melanoma NCT01893099
Study of Sorafenib/Cetuximab in Head and Neck Cancer Completed Squamous Cell Cancer NCT00815295
Phase IB/II Trial Combining Vinorelbine With Sorafenib as First-Line Treatment in Patients With Metastatic Breast Cancer Unknown status Metastatic Breast Cancer NCT00764972
Sorafenib in Treating Patients With Locally Advanced or Metastatic Liver Cancer and Cirrhosis Terminated Liver Cancer NCT00767468
A Study of BBI608 in Combination With Sorafenib, or BBI503 in Combination With Sorafenib in Adult Patients With Hepatocellular Carcinoma Active, not recruiting Hepatocellular Carcinoma NCT02279719
Sorafenib in Resected Non-small Cell Lung Carcinoma Terminated Carcinoma, Non-Small-Cell Lung NCT00532025
A Trial to Compare Surgery With Sorafenib for Hepatic Celluler Cancer With Portal Vein Tumor Thrombosis Unknown status Portal Vein Tumor Thrombus NCT03178656
Sorafenib Long Term Extension Program Active, not recruiting Neoplasms NCT00625378
Pilot Study of Effect of Sorafenib on Portal Pressure Completed Clinically Significant Portal Hypertension NCT01714609
A Randomized Phase II Trial of Surgery Plus Sorafenib vs. Sorafenib Alone for Hepatocellular Cancer (HCC) With Portal Vein Invasion Not yet recruiting Hepatocellular Cancer NCT03971201
Clinical Trial for GALNT14 Genotype - Guided, Sorafenib in Combination With TACE in Hepatocellular Carcinoma Active, not recruiting Hepatocellular Carcinoma NCT02504983
Comparison of Sequential Therapies With Sunitinib and Sorafenib in Advanced Renal Cell Carcinoma Unknown status Metastatic Renal Cell Carcinoma NCT01481870
Efficacy Study of Sorafenib and Cyclophosphamide to Treat Neuroendocrine Tumors Completed Neuroendocrine Tumors NCT00605566
Phase I Study of Gemcitabine, Sorafenib and Radiotherapy in Patients With Unresectable Pancreatic Cancer Completed Pancreatic Cancer|Adenocarcinoma of the Pancreas NCT00375310
Sorafenib Tosylate in Treating Patients With Metastatic, Locally Advanced, or Recurrent Medullary Thyroid Cancer Active, not recruiting Hereditary Thyroid Gland Medullary Carcinoma|Multiple Endocrine Neoplasia Type 2A|Multiple Endocrine Neoplasia Type 2B|Recurrent Thyroid Gland Medullary Carcinoma|Stage III Thyroid Gland Medullary Carcinoma AJCC v7|Stage IV Thyroid Gland Medullary Carcinoma AJCC v7|Stage IVA Thyroid Gland Medullary Carcinoma AJCC v7|Stage IVB Thyroid Gland Medullary Carcinoma AJCC v7|Stage IVC Thyroid Gland Medullary Carcinoma AJCC v7 NCT00390325
Sequential Melphalan for Use With Hepatic Delivery System Treatment Followed by Sorafenib in Patients With Unresectable HCC Withdrawn Hepatocellular Carcinoma (HCC) NCT02406508
Efficacy of Localized Concurrent Chemo-radiation Therapy and Sorafenib Sequential Therapy in Advanced Hepatocellular Carcinoma Completed Hepatocellular Carcinoma NCT02425605
Study Adding Multikinase Inhibitor Sorafenib to Existing Endocrine Therapy in Patients With Advanced Breast Cancer Terminated Breast Cancer NCT00525161
Monocentric Pilot Study Investigating the Metabolic Activity of Melanoma in Vivo During Sorafenib and Dacarbazine Completed Melanoma Stage III or IV|No Prior Chemotherapy NCT00794235
Sorafenib Alone Versus Sorafenib Combined With HAIC for Advanced HCC Completed Hepatocellular Carcinoma NCT02774187
Sorafenib and Paclitaxel in Treating Patients With Metastatic Breast Cancer Terminated Breast Cancer NCT00622466
Sorafenib Combined With Aspirin to Prevent the Recurrence in High-risk Patients With Hepatocellular Carcinoma Terminated Hepatocellular Carcinoma NCT02748304
Sorafenib and Thoracic Radiation for Patients With Non-Small Cell Lung Cancer Terminated Lung Cancer NCT00543335
Sorafenib Combined With Arsenical in Treating Patients With Recurrent HCC After Liver Transplantation Recruiting HCC NCT04232722
Sorafenib for Imatinib/Sunitinib-failed GIST Completed Gastrointestinal Stromal Tumors NCT01091207
Sorafenib VS TACE in HCC Patients With Portal Vein Invasion Terminated Hepatocellular Carcinoma NCT01480817
Sorafenib Treatment in Non-Small Cell Lung Cancer After Failure of Epidermal Growth Factor Receptor-tyrosine Kinase Inhibitor Completed Non-Small Cell Lung Cancer NCT00922584
Urea Cream Treatment Sorafenib-Associated HSFR in HCC Completed Hepatocellular Carcinoma NCT01934829
Fingerprint Characterization of Sorafenib Treated HCC Recruiting Hepatocellular Carcinoma|Sorafenib NCT03958669
Phase I-II Trial of Sorafenib in Combination With Ifosfamide in Soft Tissue Sarcoma Unknown status Soft Tissue Sarcoma NCT00541840
Safety and Toxicity Study of Sorafenib in Patients With Kidney Cancer Completed Carcinoma, Renal Cell NCT00445042
Radiation Therapy With Sorafenib for TACE-Resistant Hepatocellular Carcinoma Withdrawn Hepatocellular Carcinoma|Hepatocellular Cancer|Hepatoma|Liver Cancer NCT01618253
Sorafenib and Transarterial Chemoembolization for Hepatocellular Carcinoma Completed Hepatocellular Carcinoma NCT00768937
Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors With Sorafenib in Combination With Irinotecan Withdrawn Pediatric Solid Tumors NCT02747537
Neoadjuvant Chemotherapy Including Sorafenib in Women With Previously Untreated Primary Breast Cancer Completed Breast Cancer NCT00548899
E7050 in Combination With Sorafenib Versus Sorafenib Alone as First Line Therapy in Patients With Hepatocellular Carcinoma Completed Hepatocellular Carcinoma NCT01271504
HCV-RNA Kinetics During Sorafenib for Hepatocellular Carcinoma (HCC) Terminated Hepatocellular Cancer NCT01849588
Dose Escalation Study of ARQ 197 in Combination With Sorafenib in Adult Patients With Advanced Solid Tumors Completed Advanced Solid Tumors NCT00827177
TACE Combinated With Sorafenib in Treating Patients With Unresectable Hepatocellular Carcinoma Unknown status PHENYTOIN/SORAFENIB [VA Drug Interaction]|Carcinoma, Hepatocellular NCT01605734
Study of Sorafenib In Combination With Low-dose 5-fluorouracil/Cisplatin (FP) Intraarterial Infusion Chemotherapy Completed Hepatocellular Carcinoma NCT00933816
Comparing Efficacy of Sorafenib Versus Sorafenib in Combination With Low-dose FP in Patients With Advanced HCC Unknown status Advanced Hepatocellular Carcinoma|Carcinoma|Carcinoma, Hepatocellular|Liver Neoplasms|Neoplasms NCT01214343
Sorafenib and Topotecan in Refractory/Recurrent Pediatric Malignancies Completed Solid Tumor NCT01683149
Trial of Neoadjuvant Conformal Radiotherapy Plus Sorafenib for Patients With Soft Tissue Sarcoma of the Extremity and Body Wall Completed Soft Tissue Sarcoma NCT00864032
Combined Treatment of RFA and Sorafenib on Recurrent HCC Unknown status HCC|Radiofrequency Ablation|Sorafenib NCT01470495
Sorafenib in Combination With RAD001 in Advanced Solid Tumors Selected on Molecular Targets Suspended Advanced Solid Tumors NCT01226056
Pre-operative 5-Fluorouracil (5-FU) and Sorafenib With External Radiation in Locally Advanced Rectal Cancer Completed Rectal Cancer NCT01376453
Whole Brain Radiotherapy (WBRT) With Sorafenib for Breast Cancer Brain Metastases (BCBM) Active, not recruiting Breast Cancer|Brain Metastases NCT01724606
Evaluate Safety and Tolerability in Dose Escalation of Sorafenib in Advanced Renal Cell Cancer Completed Renal Cell Cancer NCT01189370
Velcade and Sorafenib in Unresected or Metastatic Renal Cell Carcinoma Terminated Metastatic Renal Cell Carcinoma NCT01100242
Sorafenib/Docetaxel Dose Escalation Trial Completed Neoplasms NCT00562523
Mechanistic Evaluation on Sorafenib Induced Hypophosphatemia. Terminated Carcinoma, Renal Cell NCT00622479
2nd Line Treatment With Pemetrexed and Sorafenib for Recurrent or Metastatic Triple Negative Breast Cancer Active, not recruiting Breast Cancer|Metastatic Breast Cancer|Recurrent Breast Cancer NCT02624700
A Study of BBI608 Administrated With Sorafenib in Adult Patients With Advanced Hepatocellular Carcinoma Completed Hepatocellular Carcinoma NCT02358395
Sorafenib Monotherapy in Inoperable/Recurrent Germ Cell Carcinoma Refractory to Chemotherapy Unknown status Testicular Cancer NCT00772694
Trametinib in Combination With Sorafenib in Patients With Advanced Hepatocellular Cancer Active, not recruiting Hepatocellular Cancer|Liver Cancer NCT02292173
Granulocyte-colony Stimulating Factor (G-CSF) and Plerixafor Plus Sorafenib for Acute Myelogenous Leukemia (AML) With FLT3 Mutations Completed Acute Myelogenous Leukemia|Leukemia NCT00943943
Study of Sorafenib and Transarterial Chemoembolization (TACE) to Treat Hepatocellular Carcinoma Completed Hepatocellular Carcinoma|Hepatoma NCT00844883
Sorafenib in Myelodysplastic Syndrome Terminated Myelodysplastic Syndromes|Leukemia, Myelomonocytic, Chronic NCT00510289
RDEA119 and Sorafenib Combination Dose Escalation Study Completed Advanced Cancer NCT00785226
Sorafenib in Hormone NaĂŻve Biochemical Recurrence of Prostate Cancer Withdrawn Prostate Cancer NCT00694291
Study of Panobinostat in Combination With Sorafenib in Kidney, Soft Tissue or Lung Cancers Completed Renal Cancer|Non Small Cell Lung Cancer (NSCLC)|Soft Tissue Sarcoma NCT01005797
Sorafenib and Dacarbazine in Soft Tissue Sarcoma Completed Sarcoma|Synovial Sarcoma|Leiomyosarcoma|Malignant Peripheral Nerve Sheath Tumor NCT00837148
Phase I/II Study of Combination of Sorafenib, Vorinostat, and Bortezomib for the Treatment of Acute Myeloid Leukemia With Complex- or Poor-risk (Monosomy 5/7) Cytogenetics or FLT3-ITD Positive Genotype Completed Acute Myeloid Leukemia NCT01534260
Sorafenib and Erlotinib or Sorafenib Alone in Advanced Non-Small Cell Lung Cancer Progressing on Erlotinib Completed Non-Small Cell Lung Cancer NCT00609804
Hepatocellular Carcinoma - Advanced Stage - Sorafenib Trial in Taiwanese Patients Completed Hepatocellular Carcinoma NCT01098760
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma Completed Hepatocellular Carcinoma NCT01008917
Sorafenib and TACE as Adjuvant Therapy for MVI in HCC Patients After Radical Resection Unknown status Hepatocellular Carcinoma NCT02537158
A Study to Compare Tivozanib (AV-951) to Sorafenib in Subjects With Advanced Renal Cell Carcinoma Completed Advanced Renal Cell Carcinoma NCT01030783
Sorafenib Tosylate With or Without Everolimus in Treating Patients With Advanced, Radioactive Iodine Refractory Hurthle Cell Thyroid Cancer Active, not recruiting Refractory Hurthle Cell Thyroid Cancer NCT02143726
Sorafenib Plus Vitamin K1 Versus Sorafenib in Advanced Hepatocellular Carcinoma Completed Hepatocellular Carcinoma NCT02259647
Study of Enzalutamide With and Without Sorafenib in Advanced Hepatocellular Carcinoma Patients Active, not recruiting Hepatocellular Carcinoma NCT02642913
Sorafenib Dose Escalation in Renal Cell Carcinoma Completed Carcinoma, Renal Cell NCT00618982
Sorafenib Tosylate Before and After Donor Bone Marrow Transplant in Treating Patients With Acute Myeloid Leukemia Active, not recruiting Acute Myeloid Leukemia With FLT3/ITD Mutation NCT01578109
Transcatheter Arterial Chemoembolization Therapy In Combination With Sorafenib Unknown status Hepatocellular Carcinoma|Unresectable Hepatocellular Carcinoma|Carcinoma, Hepatocellular|Liver Neoplasm NCT01217034
Effectiveness and Safety Study of TACE Plus Oral Sorafenib for Unresectable HCC Terminated Carcinoma, Hepatocellular NCT00576056
Sorafenib and Nivolumab in Treating Participants With Unresectable, Locally Advanced or Metastatic Liver Cancer Recruiting Stage III Hepatocellular Carcinoma AJCC v8|Stage IIIA Hepatocellular Carcinoma AJCC v8|Stage IIIB Hepatocellular Carcinoma AJCC v7|Stage IIIC Hepatocellular Carcinoma AJCC v7|Stage IV Hepatocellular Carcinoma AJCC v8|Stage IVA Hepatocellular Carcinoma AJCC v8|Stage IVB Hepatocellular Carcinoma AJCC v8 NCT03439891
A Phase Ib Study of Stereotactic Body Radiotherapy (SBRT) Plus Sorafenib in Patients With Unresectable Hepatocellular Carcinoma (HCC) Withdrawn Hepatocellular Carcinoma NCT01801163
A Study of Combination of Gemcitabine, Oxaliplatin (GEMOX)-Sorafenib in Patients With Advanced Biliary Tract Cancer Terminated Cholangiocarcinoma|Biliary Tract Cancer|Gallbladder Cancer NCT00955721
Sorafenib Tosylate With or Without Everolimus in Treating Patients With Localized, Unresectable, or Metastatic Liver Cancer Completed Liver Cancer NCT01005199
Safety Study of Sorafenib Following Combined Therapy of Radiation and TACE for Liver Cancer Unknown status Hepatocellular Carcinoma NCT00999843
EVESOR: a Phase 1 Trial of Everolimus and Sorafenib Unknown status Metastatic or Locally Advanced Solid Tumors NCT01932177
Sorafenib Plus S-1 in Advanced Solid Tumors Completed Advanced Solid Tumors NCT01128998
XIAP Antisense AEG35156 in Combination With Sorafenib in Patients With Advanced Hepatocellular Carcinoma (HCC) Completed Advanced Hepatocellular Carcinoma NCT00882869
Phase 3 Study of BGB-A317 Versus Sorafenib in Patients With Unresectable HCC Active, not recruiting Hepatocellular Carcinoma (HCC) NCT03412773
Sorafenib Monotherapy vs. TACE-sorafenib Sequential Therapy for HCC With Metastasis Recruiting Hepatocellular Carcinoma|Metastasis NCT03518502
TACE and Sorafenib for Advanced Hepatocellular Carcinoma (HCC) Terminated Hepatocellular Carcinoma NCT00618384
Study of Curcumin, Vorinostat, and Sorafenib Withdrawn Advanced Cancers NCT01608139
Riluzole and Sorafenib Tosylate in Treating Patients With Advanced Solid Tumors or Melanoma Active, not recruiting Advanced Malignant Solid Neoplasm|Recurrent Melanoma|Refractory Malignant Solid Neoplasm|Stage III Cutaneous Melanoma AJCC v7|Stage IIIA Cutaneous Melanoma AJCC v7|Stage IIIB Cutaneous Melanoma AJCC v7|Stage IIIC Cutaneous Melanoma AJCC v7|Stage IV Cutaneous Melanoma AJCC v6 and v7 NCT01303341
Study of Sorafenib and Gemcitabine in Advanced Hepatocellular Carcinoma (HCC) Unknown status Hepatocellular Carcinoma NCT00844688
A Study of BBI503 in Advanced Solid Tumors, or BBI503/ Sorafenib in Advanced Hepatocellular Carcinoma Completed Advanced Solid Tumors|Hepatocellular Carcinoma NCT02354898
Phase I Study of Vorinostat and Sorafenib in Advanced Cancer Completed Malignant Solid Tumour|Renal Cell Carcinoma|Non Small Cell Lung Carcinoma NCT00635791
Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas Recruiting Brain Tumor|Glioblastoma|Anaplastic Glioma NCT01434602
Single-arm Study to Evaluate the Safety and Efficacy of Sorafenib, in Subjects With BRAF Mutation Refractory Solid Tumors Completed Refractory Solid Tumors NCT02450149
A Study to Compare Tivozanib Hydrochloride to Sorafenib in Subjects With Refractory Advanced RCC Active, not recruiting Carcinoma, Renal Cell NCT02627963
Sorafenib to Overcome Resistance to Systemic Chemotherapy in Androgen-independent Prostate Cancer Completed Prostate Cancer NCT00414388
MLN0128 Compared to Sorafenib in Advanced or Metastatic Hepatocellular Carcinoma Active, not recruiting Hepatocellular Carcinoma|Liver Cancer|HCC NCT02575339
Study of Sorafenib and Palliative Radiotherapy in Kidney Cancer That Spreads to the Bone Completed Renal Cell Carcinoma NCT00609934
Sorafenib in Treating Patients With Metastatic Kidney Cancer That Has Not Responded to Sunitinib or Bevacizumab Completed Kidney Cancer NCT00866320
Phase III Study of Sorafenib in Patients With Renal Cell Carcinoma (RCC) Completed Carcinoma, Renal Cell NCT00586105
Refametinib in Combination With Sorafenib in RAS Mutant Hepatocellular Carcinoma (HCC) Completed Carcinoma, Hepatocellular NCT01915602
PK Trial of Sorafenib & Erlotinib in Patients With Refractory Solid Tumors Completed Refractory Solid Tumors NCT00759928
Sorafenib Trial in Advanced and/or Recurrent Gastric Adenocarcinoma: Treatment Evaluation: STARGATE Completed Malignant Neoplasm of Stomach|Effects of Chemotherapy NCT01187212
Pilot Study Sorafenib as Bridge to Orthotopic Liver Transplantation (OLT) Terminated Carcinoma, Hepatocellular NCT01337492
Efficacy and Safety of Sorafenib as Adjuvant and Latter Radiofrequency Ablation for Recurrent Hepatocellular Carcinoma Unknown status HCC NCT03097848
Sorafenib/ Carboplatin/ Paclitaxel in Patients With Solid Tumors Completed Neoplasms NCT00606125
Radiofrequency Ablation Accompanied With Spontaneous Sorafenib in Early to Intermediate Stage HCC Unknown status HCC NCT02187081
Sorafenib Tosylate and Pembrolizumab in Treating Patients With Advanced or Metastatic Liver Cancer Recruiting Advanced Adult Hepatocellular Carcinoma|Child-Pugh Class A|Stage III Hepatocellular Carcinoma|Stage IIIA Hepatocellular Carcinoma|Stage IIIB Hepatocellular Carcinoma|Stage IIIC Hepatocellular Carcinoma|Stage IV Hepatocellular Carcinoma|Stage IVA Hepatocellular Carcinoma|Stage IVB Hepatocellular Carcinoma NCT03211416
An Extension Treatment Protocol for Subjects Who Have Participated in a Phase 3 Study of Tivozanib Versus Sorafenib in Renal Cell Carcinoma (Protocol AV-951-09-301) Completed Advanced Renal Cell Carcinoma NCT01076010
Activity of Sorafenib in Salivary Gland Cancer Completed Salivary Gland Cancer NCT01703455
Phase I Study of Sorafenib Dosed Continuously With Cyclophosphamide and Doxorubicin Completed Cancer NCT00562913
Sorafenib as a Second Line Treatment in Patients With Advanced or Metastatic Gastric Cancer Terminated Gastric Cancer NCT00595985
Study of the Pharmacokinetics/Safety of Sorafenib + Capecitabine in Advanced Solid Tumors Completed Refractory Malignancy NCT00613145
Dosing and Effectiveness Study of Sorafenib and RAD001 in the Treatment of Patients With Advanced Kidney Cancer Completed Kidney Cancer NCT00392821
Sorafenib Tosylate in Treating Patients With Desmoid Tumors or Aggressive Fibromatosis Active, not recruiting Desmoid-Type Fibromatosis NCT02066181
Sorafenib and FOLFIRI Regimen in 2nd Colorectal Cancer (CRC) After Failure of Oxaliplatin Treatment Unknown status Colorectal Neoplasms NCT00839111
A 3rd/4th Line Placebo-controlled Trial of Sorafenib in Patients With Predominantly Non Squamous Non-Small Cell Lung Cancer (NSCLC). Completed Carcinoma|Non-Small-Cell Lung NCT00863746
Phase I/II Trial of Sorafenib Plus Ixabepilone in HER2-Negative Metastatic Breast Cancer Completed Metastatic Breast Cancer NCT00825734
Phase I Study With Sorafenib in Addition to Vinflunine in Metastatic Transitional Cell Carcinoma of the Urothelial Tract Completed Urothelial Carcinoma|Bladder Cancer|Renal Pelvis Cancer|Ureter Cancer|Urethra Cancer NCT01844947
Gemcitabine and Split-dose Cisplatin (GC) Plus Sorafenib in Chemotherapy-naĂŻve Patients With Locally Advanced or Metastatic Urothelial Carcinoma Terminated Bladder Cancer|URINARY BLADDER NCT00714948
Sorafenib and Bevacizumab to Treat Ovarian, Fallopian and Peritoneal Cancer Completed Ovarian Neoplasm|Fallopian Tube Cancer|Primary Peritoneal Cancer NCT00436215
Study of Mapatumumab in Combination With Sorafenib in Subjects With Advanced Hepatocellular Carcinoma Completed Carcinoma, Hepatocellular NCT01258608
Sorafenib Tosylate With or Without Stereotactic Body Radiation Therapy in Treating Patients With Liver Cancer Recruiting Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer NCT01730937
4SC-201 (Resminostat) and Sorafenib in Advanced Hepatocellular Carcinoma Completed Hepatocellular Carcinoma NCT00943449
Sorafenib as Neoadjuvant Therapy Before Cytoreductive Nephrectomy in Patients With Metastatic Renal Cell Carcinoma Completed Carcinoma, Renal Cell NCT01982097
Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia Completed Blastic Phase|Childhood Acute Promyelocytic Leukemia With PML-RARA|Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Childhood Solid Neoplasm|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Juvenile Myelomonocytic Leukemia|Philadelphia Chromosome Negative, BCR-ABL1 Positive Chronic Myelogenous Leukemia|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Recurrent Disease NCT01445080
A Phase II Study of BAY 43-9006 (Sorafenib) in Metastatic, Androgen-Independent Prostate Cancer Completed Prostate Cancer NCT00090545
Randomized Study of Sorafenib Dose Escalation in Patients With Previously Untreated Metastatic Renal Cell Carcinoma Terminated Renal Cell Carcinoma NCT00557830
Sorafenib in Treating Patients With Advanced Anaplastic Thyroid Cancer Terminated Anaplastic Thyroid Cancer|Recurrent Thyroid Cancer NCT00126568
Sorafenib Plus Capecitabine Efficacy Assessment in Patients With Advanced Pre-treated Colorectal Cancer Completed Colorectal Cancer NCT01290926
Sorafenib Phase II Study for Japanese Anaplastic or Medullary Thyroid Carcinoma Patients Completed Thyroid Carcinoma NCT02114658
Sorafenib Plus Hepatic Arterial Infusion Versus Sorafenib for HCC With Major Portal Vein Tumor Thrombosis Unknown status HepatoCellular Carcinoma|Portal Vein Thrombosis NCT03009461
BATTLE Program: Sorafenib in Patients With NSCLC Completed Lung Cancer NCT00411671
Sorafenib and Bavituximab Plus SBRT in Unresectable Hepatocellular Carcinoma Withdrawn HepatoCellular Carcinoma|Unresectable HepatoCellular Carcinoma|Liver Cancer NCT02989870
Dose Escalation Study of Sorafenib and Irinotecan Combination Therapy in Pediatric Patients With Solid Tumors Completed Rhabdomyosarcoma and Other Soft Tissue Sarcomas|Ewing's Sarcoma Family of Tumors|Osteosarcoma|Neuroblastoma|Brain Tumors NCT01518413
Study of Sorafenib in Patients With Advanced Renal Cell Carcinoma Completed Metastatic Renal Cell Carcinoma NCT00848640
Bortezomib, Sorafenib Tosylate, and Decitabine in Treating Patients With Acute Myeloid Leukemia Active, not recruiting Acute Myeloid Leukemia|Recurrent Adult Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Therapy-Related Acute Myeloid Leukemia NCT01861314
Trial of Gemcitabine, Carboplatin, and Sorafenib in Chemotherapy-naive Patients With Advanced/Metastatic Bladder Carcinoma Completed Bladder Cancer NCT00461851
Nexavar Post-marketing Surveillance for Renal Cell Carcinoma in Japan Completed Carcinoma, Renal Cell NCT01411423
Study of Safety and Tolerability of PDR001 in Combination With Sorafenib and to Identify the Maximum Tolerated Dose and/or Phase 2 Dose for This Combination in Advanced Hepatocellular Patients Active, not recruiting Hepatocellular Carcinoma NCT02988440
Study to Compare Selective Internal Radiation Therapy (SIRT) Versus Sorafenib in Locally Advanced Hepatocellular Carcinoma (HCC) Active, not recruiting Hepatocellular Carcinoma NCT01135056
Nexavar Post-marketing Surveillance for RCC in Japan: Early Access Program Completed Carcinoma, Renal Cell NCT01412671
Proton Beam Radiotherapy Plus Sorafenib Versus Sorafenib for Patients With Hepatocellular Carcinoma Exceeding San Francisco Criteria Unknown status Carcinoma, Hepatocellular NCT01141478
Sorafenib Plus Doxorubicin in Patients With Advanced Hepatocellular Carcinoma With Disease Progression on Sorafenib Active, not recruiting Hepatocellular Carcinoma NCT01840592
Sorafenib in Treating Patients With Recurrent or Progressive Malignant Glioma Completed Adult Anaplastic Astrocytoma|Adult Anaplastic Oligodendroglioma|Adult Giant Cell Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor NCT00093613
Sorafenib Tosylate and Hypoxia-Activated Prodrug TH-302 in Treating Patients With Advanced Kidney Cancer or Liver Cancer That Cannot Be Removed By Surgery Completed Kidney Cancer|Liver Cancer NCT01497444
Study of SIR-Spheres Plus Sorafenib as 1st Line Treatment for Non-resectable Primary Hepatocellular Carcinoma (HCC) Completed Hepatocellular Carcinoma NCT00712790
Sorafenib Concomitantly Used With TACE (Transarterial Chemoembolization) in uHCC (Unresectable Hepatocellular Carcinoma) Patients in China Completed Carcinoma, Hepatocellular NCT01839630
Effect of Sorafenib on ccRCC Uptake of Radiolabeled Bevacizumab or cG250 Completed Clear Cell Renal Cell Carcinoma NCT00602862
Sorafenib Plus Doxorubicin Versus Sorafenib Alone for the Treatment of Advanced Hepatocellular Carcinoma: a Randomized Phase II Trial Unknown status Liver Carcinoma NCT01272557
Sorafenib in Treating Patients Undergoing Surgery for Stage II, Stage III, or Stage IV Kidney Cancer Completed Kidney Cancer NCT00405366
Efficacy of Sorafenib Added to Standard Primary Therapy in Elderly Patients With Newly Diagnosed AML Completed Acute Myeloid Leukemia NCT00373373
Sorafenib in Relapsed High Grade Osteosarcoma Completed Osteosarcoma NCT00889057
Study of Dalantercept and Sorafenib in Patients With Advanced Hepatocellular Carcinoma Completed Advanced Adult Hepatocellular Carcinoma NCT02024087
Sorafenib and Fulvestrant in Treating Patients With Locally Advanced or Metastatic Breast Cancer That Did Not Respond to Aromatase Inhibitor Therapy Terminated Breast Cancer NCT00722072
Erlotinib and Sorafenib in Chemonaive Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer Unknown status Non-Small Cell Lung Cancer NCT00722969
Safety, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of Sorafenib and Eribulin in Combination Completed Neoplasms NCT01585870
Sorafenib in Combination With Irinotecan in Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors Completed Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors NCT01715441
Nexavar Post-marketing Surveillance for Hepatocellular Carcinoma in Japan Completed Carcinoma, Hepatocellular NCT01411436
Efficacy and Safety Study of Sorafenib With Topotecan in Patients With Platinum-resistant Recurrent Ovarian Cancer Completed Ovarian Cancer NCT01047891
Use of Sorafenib and/or Regorafenib in Liver Cancer (Hepatocellular Carcinoma) Subsequent to Another Systemic First-line Treatment Terminated Hepatocellular Carcinoma NCT03644511
Sorafenib in Treating Patients With Refractory Non-Small Cell Lung Cancer Completed Lung Cancer NCT00064350
Pemetrexed Disodium and Sorafenib Tosylate in Treating Patients With Advanced Solid Tumors Completed Unspecified Adult Solid Tumor NCT01450384
CS1008- in Combination With Sorafenib Compared to Sorafenib Alone in Subjects With Advanced Liver Cancer Completed Advanced Hepatocellular Carcinoma|Liver Cancer|Hepatic Cancer|Liver Neoplasms NCT01033240
Phase I Portion of Phase I/II Sorafenib With Radiation and Temozolomide in Newly Diagnosed Glioblastoma or Gliosarcoma Terminated Glioblastoma|Gliosarcoma NCT00734526
Interleukin-2 With Sorafenib (BAY 43-9006) for Unresectable or Metastatic Clear Cell Renal Carcinoma (RCC) and Metastatic Melanoma Completed Renal Cancer|Melanoma NCT00418496
Phase I-II Study of Idarubicin, Cytarabine, and Sorafenib (BAY43-9006) Completed AML|Acute Myeloid Leukemia|Myelodysplastic Disorders NCT00542971
A Phase I/II Study of Cisplatin and Radiation in Combination With Sorafenib in Cervical Cancer Completed Cancer of the Cervix NCT00510250
Outcomes of HCC (Hepatocellular Carcinoma) Patients Treated With TACE (Transarterial Chemoembolization) and Early, Not Early or Not at All Followed by Sorafenib Completed Carcinoma, Hepatocellular NCT01933945
The Effects of Sorafenib on Molecular Barrett's Esophagus Cancer Terminated Esophageal Cancer NCT00619242
Sorafenib and Micro-therapy Guided by Primovist Enhanced MRI in Patients With Inoperable Liver Cancer Completed Hepatocellular Carcinoma NCT01126645
Preoperative Trial of Sorafenib in Combination With Cisplatin Followed by Paclitaxel for Early Stage Breast Cancer Terminated Breast Cancer NCT01194869
DCE-MRI Using Dotarem® in Evaluation of Therapeutic Response to Sorafenib in Patients With Advanced Stage HCC Terminated Hepatocellular Carcinoma NCT01806740
Phase I Study of Weekly Topotecan in Combination With Sorafenib in Treatment of Relapsed Small Cell Lung Cancer Completed Small Cell Carcinoma|Lung Cancer NCT00466232
Sorafenib Tosylate and Erlotinib Hydrochloride in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gallbladder Cancer or Cholangiocarcinoma Completed Extrahepatic Bile Duct Adenocarcinoma|Gallbladder Adenocarcinoma|Gallbladder Adenocarcinoma With Squamous Metaplasia|Hilar Cholangiocarcinoma|Recurrent Extrahepatic Bile Duct Carcinoma|Recurrent Gallbladder Carcinoma|Undifferentiated Gallbladder Carcinoma|Unresectable Extrahepatic Bile Duct Carcinoma|Unresectable Gallbladder Carcinoma NCT01093222
A Study to Assess Sorafenib Alone and in Combination With Low-Dose Interferon Following Unsuccessful Treatment With Sunitinib in Patients With Advanced Renal Cell Cancer. Terminated Carcinoma, Renal Cell NCT00678288
Temsirolimus + Sorafenib in Advanced Hepatocellular Carcinoma (HCC) Withdrawn Hepatocellular Carcinoma NCT01335074
A Randomized Controlled Trial Comparing Safety and Efficacy of Carboplatin and Paclitaxel Plus or Minus Sorafenib (BAY 43-9006) in Chemonaive Patients With Stage IIIB-IV Non-Small Cell Lung Cancer (NSCLC) Terminated Carcinoma, Non-Small Cell Lung NCT00300885
Sorafenib Tosylate in Treating Patients With Recurrent Aggressive Non-Hodgkin's Lymphoma Completed Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Hepatosplenic T-cell Lymphoma|Peripheral T-cell Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma NCT00131937
Nexavar Dosing in Renal Cancer Patients in "Real-life" Setting Completed Carcinoma, Renal Cell NCT01557127
Sorafenib Tosylate in Treating Patients With Liver Cancer Who Have Undergone a Liver Transplant Completed Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Localized Resectable Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer NCT00844168
Randomized Trial Sorafenib-Pravastatin Versus Sorafenib Alone for the Palliative Treatment of Child-Pugh A Hepatocellular Carcinoma Completed Child-Pugh A Hepatocellular Carcinoma NCT01903694
SorAfenib Versus RADIOEMBOLIZATION in Advanced Hepatocellular Carcinoma Completed Liver Carcinoma NCT01482442
Study of Sorafenib With Combination of Thalidomide in Hepatocellular Carcinoma (HCC) Terminated Hepatocellular Carcinoma NCT00971126
Phase I/II Trial of Letrozole and Sorafenib in Post-Menopausal Hormone-Receptor + Breast Cancer Active, not recruiting Metastatic Breast Cancer NCT00634634
Study of Dovitinib Versus Sorafenib in Patients With Metastatic Renal Cell Carcinoma Completed Metastatic Renal Cell Carcinoma NCT01223027
Sorafenib in Treating Patients Who Are Undergoing Surgery for Metastatic Kidney Cancer Terminated Clear Cell Renal Cell Carcinoma|Recurrent Renal Cell Cancer|Stage IV Renal Cell Cancer NCT00126659
An Expanded Cohort Trial of Bortezomib and Sorafenib in Advanced Malignant Melanoma Completed Melanoma NCT01078961
Using Sorafenib as a Salvage Treatment for Relapsed or Refractory Acute Myeloid Leukemia Carrying Fms-related Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Recruiting FLT3-ITD Mutation|AML NCT03622541
A Phase I Trial Evaluating mFOLFOX6 and Avastin With Nexavar as First-Line Treatment for Metastatic Colorectal Cancer Terminated Metastatic Colorectal Cancer NCT00779311
Capecitabine and Cisplatin (XP)+Sorafenib in Advanced Gastric Cancer (AGC): Sorafenib+XP Completed Advanced Gastric Cancer NCT00565370
Phase I Study of Bevacizumab and Sorafenib Combined With Low Dose Cyclophosphamide in Patients With Refractory Solid Tumors and Leukemia Completed Refractory Solid Tumors|Leukemia NCT00665990
Sorafenib in Combination With Cytarabine and Clofarabine in Patients With Refractory or Relapsed Hematologic Malignancies Completed Acute Myeloid Leukemia|Infantile Leukemia (Both AML and ALL)|Myelodysplastic Syndrome|Myelodysplastic/Myeloproliferative Neoplasms|Biphenotypic Leukemia NCT00908167
Sorafenib and Everolimus in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma Completed Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm NCT00474929
Sorafenib Plus Paclitaxel in Adreno-Cortical-Cancer Patients Unknown status Adrenocortical Carcinoma NCT00786110
Sorafenib With Irinotecan in Metastatic Colorectal Cancer (mCRC) and K-RAS Mutation Completed Metastatic Colorectal Cancer NCT00989469
Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors Active, not recruiting Cirrhosis|Hepatitis B Infection|Hepatitis C Infection|Metastatic Malignant Solid Neoplasm|Recurrent Hepatocellular Carcinoma|Recurrent Malignant Solid Neoplasm|Refractory Malignant Neoplasm|Stage IV Hepatocellular Carcinoma AJCC v7|Unresectable Solid Neoplasm NCT02143401
A Randomized, Double-Blinded, Placebo-Controlled Study of Sorafenib in Patients With Advanced Hepatocellular Carcinoma Completed Carcinoma, Hepatocellular NCT00492752
A Phase II Study of Bevacizumab + Sorafenib in Metastatic Breast Cancer Terminated Metastatic Breast Cancer NCT00632541
PEG-Interferon Alfa-2b and Sorafenib in Treating Patients With Unresectable or Metastatic Kidney Cancer Terminated Kidney Cancer NCT00589550
Sorafenib and RAD001 Renal Cell Carcinoma Completed Renal Cell Carcinoma NCT00384969
BAY 43-9006 (Sorafenib) to Treat Relapsed Non-Small Cell Lung Cancer Completed Non-Small-Cell Lung Carcinoma NCT00098254
Sorafenib in Treating Patients With Persistent or Recurrent Ovarian Epithelial or Peritoneal Cancer Completed Primary Peritoneal Carcinoma|Recurrent Ovarian Carcinoma NCT00093626
Sorafenib Tosylate and Yttrium Y 90 Glass Microspheres in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery Active, not recruiting Advanced Adult Hepatocellular Carcinoma|BCLC Stage C Hepatocellular Carcinoma|Recurrent Adult Hepatocellular Carcinoma|Stage III Hepatocellular Carcinoma AJCC v7|Stage IIIA Hepatocellular Carcinoma AJCC v7|Stage IIIB Hepatocellular Carcinoma AJCC v7|Stage IIIC Hepatocellular Carcinoma AJCC v7|Stage IV Hepatocellular Carcinoma AJCC v7|Stage IVA Hepatocellular Carcinoma AJCC v7|Stage IVB Hepatocellular Carcinoma AJCC v7|Unresectable Hepatocellular Carcinoma NCT01900002
Sorafenib in Treating Patients With Relapsed Chronic Lymphocytic Leukemia Terminated Refractory Chronic Lymphocytic Leukemia|Stage I Chronic Lymphocytic Leukemia|Stage II Chronic Lymphocytic Leukemia|Stage III Chronic Lymphocytic Leukemia|Stage IV Chronic Lymphocytic Leukemia NCT00303966
Vemurafenib With Sorafenib Tosylate or Crizotinib in Treating Patients With Advanced Malignancies With BRAF Mutations Active, not recruiting Advanced Malignant Neoplasm|BRAF Gene Mutation|Metastatic Malignant Neoplasm|Recurrent Malignant Neoplasm|Refractory Malignant Neoplasm NCT01531361
Sorafenib Tosylate With or Without Pravastatin in Treating Patients With Liver Cancer and Cirrhosis Completed Liver Cancer NCT01075555
Sorafenib as Adjuvant Treatment in the Prevention Of Recurrence of Hepatocellular Carcinoma (STORM) Completed Carcinoma, Hepatocellular NCT00692770
Sorafenib/Erlotinib Versus Erlotinib Alone in Previously Treated Advanced Non-Small-Cell Lung Cancer (NSCLC) Completed Non-Small Cell Lung Cancer NCT00600015
Trial of S-1 in Combination With Sorafenib for Patients With Advanced Hepatocellular Carcinoma Completed Hepatocellular Carcinoma NCT01131689
Sorafenib Tosylate, Valproic Acid, and Sildenafil Citrate in Treating Patients With Recurrent High-Grade Glioma Recruiting Glioblastoma|Recurrent Adult Brain Neoplasm|Malignant Glioma|WHO Grade III Glioma NCT01817751
Effect of BAY 43-9006 (Sorafenib) on Cardiovascular Safety Parameters in Cancer Patients Completed Neoplasms NCT00259129
The Effect of Telephone Counseling on the Compliance and Satisfaction for Advanced HCC Patients Receiving Sorafenib Unknown status Hepatocellular Carcinoma NCT02564666
Letrozole Plus Oral Cyclophosphamide Plus/Minus Sorafenib as Primary Systemic Treatment in Breast Cancer Patients Unknown status Breast Cancer NCT00954135
Sorafenib Tosylate and Bevacizumab in Treating Patients With Advanced Kidney Cancer Completed Chromophobe Renal Cell Carcinoma|Clear Cell Renal Cell Carcinoma|Papillary Renal Cell Carcinoma|Recurrent Renal Cell Carcinoma|Sarcomatoid Renal Cell Carcinoma|Stage IV Renal Cell Cancer NCT00126503
Sorafenib in Treating Patients With Malignant Gastrointestinal Stromal Tumor That Progressed During or After Previous Treatment With Imatinib Mesylate and Sunitinib Malate Active, not recruiting Gastrointestinal Stromal Tumor NCT00265798
Study of Bavituximab and Sorafenib In Patients With Advanced Liver Cancer Completed Hepatocellular Carcinoma|Liver Cancer NCT01264705
Paclitaxel and Carboplatin With Or Without Sorafenib In The First-Line Treatment Of Patients With Ovarian Cancer Completed Ovarian Cancer NCT00390611
Sorafenib in Treating Patients With Relapsed or Refractory Multiple Myeloma Completed Refractory Multiple Myeloma NCT00253578
S0505 Sorafenib in Treating Patients With Advanced Soft Tissue Sarcomas Completed Sarcoma NCT00217620
Sorafenib in Treating Patients With Metastatic or Unresectable Solid Tumors, Multiple Myeloma, or Non-Hodgkin's Lymphoma With or Without Impaired Liver or Kidney Function Completed Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Refractory Multiple Myeloma|Splenic Marginal Zone Lymphoma|Stage II Multiple Myeloma|Stage III Adult Burkitt Lymphoma|Stage III Adult Diffuse Large Cell Lymphoma|Stage III Adult Diffuse Mixed Cell Lymphoma|Stage III Adult Diffuse Small Cleaved Cell Lymphoma|Stage III Adult Immunoblastic Large Cell Lymphoma|Stage III Adult Lymphoblastic Lymphoma|Stage III Grade 1 Follicular Lymphoma|Stage III Grade 2 Follicular Lymphoma|Stage III Grade 3 Follicular Lymphoma|Stage III Mantle Cell Lymphoma|Stage III Marginal Zone Lymphoma|Stage III Multiple Myeloma|Stage III Small Lymphocytic Lymphoma|Stage IV Adult Burkitt Lymphoma|Stage IV Adult Diffuse Large Cell Lymphoma|Stage IV Adult Diffuse Mixed Cell Lymphoma|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma|Stage IV Adult Immunoblastic Large Cell Lymphoma|Stage IV Adult Lymphoblastic Lymphoma|Stage IV Grade 1 Follicular Lymphoma|Stage IV Grade 2 Follicular Lymphoma|Stage IV Grade 3 Follicular Lymphoma|Stage IV Mantle Cell Lymphoma|Stage IV Marginal Zone Lymphoma|Stage IV Small Lymphocytic Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific|Waldenström Macroglobulinemia NCT00118170
Phase II Trial of Sorafenib Combined With Concurrent HAIC for Hepatocellular Carcinoma Completed Hepatocellular Carcinoma NCT02981498
BAY43-9006 - Phase II in Advanced Breast Cancer Completed Breast Neoplasms|Breast Cancer NCT00101400
Study Of Sunitinib Malate Versus Sorafenib In Patients With Inoperable Liver Cancer Terminated Carcinoma, Hepatocellular NCT00699374
Sorafenib in Treating Patients With Extensive Stage Small Cell Lung Cancer Completed Extensive Stage Small Cell Lung Cancer|Recurrent Small Cell Lung Cancer NCT00182689
Study of Plitidepsin in Combination With Sorafenib or Gemcitabine in Patients With Advanced Solid Tumors or Lymphomas Completed Advanced Solid Tumors|Lymphomas NCT00788099
A Randomized, Controlled Phase III Trial of Sorafenib With or Without cTACE in Patients With Advanced HCC Completed Advanced Adult Hepatocellular Carcinoma NCT01829035
Sorafenib + mFOLFOX for Hepatocellular Carcinoma Active, not recruiting Hepatocellular Cancer NCT01775501
Pharmacokinetic Study of BAY43-9006 and Taxotere to Treat Patient With Prostatic Cancer Completed Primary Disease|Prostate Cancer NCT00405210
Phase 2 Study of Sorafenib Plus HAIC of FOLFOX vs. Sorafenib Plus HAIC of OXA for Advanced HCC Recruiting Hepatocellular Carcinoma NCT03812770
Lenalidomide in Combination With a Fixed Dose of Sorafenib for the Treatment of Hepatocellular Carcinoma Terminated Hepatocellular Carcinoma NCT01348503
Sorafenib and Bortezomib Treatment for Relapsed or Refractory Multiple Myeloma Patients Completed Multiple Myeloma NCT00536575
Sorafenib in Treating Patients With Regional or Metastatic Cancer of the Urothelium Terminated Adenocarcinoma of the Bladder|Distal Urethral Cancer|Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter|Proximal Urethral Cancer|Recurrent Bladder Cancer|Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter|Recurrent Urethral Cancer|Regional Transitional Cell Cancer of the Renal Pelvis and Ureter|Squamous Cell Carcinoma of the Bladder|Stage III Bladder Cancer|Stage IV Bladder Cancer|Transitional Cell Carcinoma of the Bladder|Urethral Cancer Associated With Invasive Bladder Cancer NCT00112905
An Investigational Immuno-therapy Study of Nivolumab Compared to Sorafenib as a First Treatment in Patients With Advanced Hepatocellular Carcinoma Active, not recruiting Hepatocellular Carcinoma NCT02576509
Metastatic Advanced Pancreas Sorafenib Unknown status Locally Advanced Pancreatic Cancer NCT00758381
Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable Melanoma Completed Melanoma|Recurrent Melanoma|Stage III Melanoma|Stage IV Melanoma NCT00349206
Sorafenib Tosylate Before and After Hepatic Arterial Chemoembolization With Doxorubicin Hydrochloride and Mitomycin C in Treating Patients With Localized Liver Cancer That Cannot Be Removed by Surgery Completed Liver Cancer NCT00949182
Efficacy and Safety Study of Sorafenib Plus Pravastatin to Treat Advanced Hepatocarcinoma Completed Advanced Hepatocarcinoma NCT01418729
Randomized Phase II Trial of Chemoembolization and Sorafenib Withdrawn Hepatocellular Carcinoma NCT02908165
Tipifarnib and Sorafenib Tosylate in Treating Patients With Biopsiable Advanced Cancer Completed Advanced Malignant Neoplasm NCT00244972
Sorafenib and Bortezomib in Treating Patients With Advanced Cancer Completed Refractory Chronic Lymphocytic Leukemia|Refractory Multiple Myeloma|Stage III Multiple Myeloma|Stage IV Chronic Lymphocytic Leukemia|Unspecified Adult Solid Tumor, Protocol Specific NCT00303797
Sorafenib and Vinorelbine in Treating Women With Stage IV Breast Cancer Completed Breast Cancer NCT00828074
Study of Combination of Sorafenib With Cisplatin and 5-fluorouracil as First-line Treatment of Recurrence After Radiotherapy Patients Who Failed With Radiotherapy in Recurrent or Metastatic Nasopharyngeal Carcinoma (NPC) Completed Nasopharyngeal Neoplasms NCT00747799
A Study of Sorafenib in Patients With Chemonaive Metastatic Uveal Melanoma Unknown status Uveal Melanoma NCT01377025
Sorafenib With Capecitabine and Oxaliplatin for Advanced or Metastatic Hepatocellular Carcinoma Unknown status Advanced Hepatocellular Carcinoma|Metastatic Hepatocellular Carcinoma NCT00752063
Global Study Looking at the Combination of RAD001 and Sorafenib to Treat Patients With Advanced Hepatocellular Carcinoma Terminated Hepatocellular Carcinoma NCT00828594
A Phase III Study of Sorafenib in Patients With Advanced Hepatocellular Carcinoma Completed Carcinoma, Hepatocellular NCT00105443
Sorafenib in BAC or Never-Smokers With Lung Adenocarcinoma Completed Lung Cancer NCT00456716
HAIC Plus Toripalimab vs. HAIC Plus Sorafenib for HCC With PVTT: a Non-comparative, Prospective, Randomized Trial Recruiting Hepatocellular Carcinoma NCT04135690
Study of Sorafenib With or Without VT-122 in Patients With Hepatocellular Carcinoma (HCC) Unknown status HCC NCT01265576
A Phase II Randomized, Double-blind, Placebo-controlled Study of Sorafenib or Placebo in Combination With Transarterial Chemoembolization (TACE) Performed With DC Bead and Doxorubicin for Intermediate Stage Hepatocellular Carcinoma (HCC). Completed Carcinoma, Hepatocellular NCT00855218
Everolimus/Sorafenib or Sunitinib in Patients With Metastatic Renal Cell Carcinoma (RCC) Withdrawn Locally Metastatic Malignant Neoplasm NCT01616186
External-Beam Radiation Therapy, Capecitabine, and Sorafenib in Treating Patients With Locally Advanced Rectal Cancer Completed Colorectal Cancer NCT00869570
Entinostat and Sorafenib Tosylate in Treating Patients With Advanced or Metastatic Solid Tumors or Refractory or Relapsed Acute Myeloid Leukemia Terminated Adult Acute Basophilic Leukemia|Adult Acute Eosinophilic Leukemia|Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13 NCT01159301
ET 140202 -T Cell Combined With TAE or Sorafenib in the Treatment of Liver Cancer Recruiting Hepatocellular Carcinoma|Liver Cancer|Liver Neoplasms|Metastatic Liver Cancer NCT03965546
A Study of Atezolizumab in Combination With Bevacizumab Compared With Sorafenib in Patients With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma [IMbrave150] Recruiting Carcinoma, Hepatocellular NCT03434379
Lenvatinib Plus TACE Versus Sorafenib Plus TACE for HCC With PVTT Enrolling by invitation Carcinoma, Hepatocellular|Portal Vein Tumor Thrombus NCT04127396
Sorafenib Study: Dosing in Patients With Pulmonary Arterial Hypertension (PAH) Completed Pulmonary Arterial Hypertension NCT00452218
Sorafenib Tosylate, Cisplatin, and Docetaxel in Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Completed Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma|Recurrent Metastatic Squamous Neck Cancer With Occult Primary|Recurrent Salivary Gland Cancer|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Salivary Gland Squamous Cell Carcinoma|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IVA Salivary Gland Cancer|Stage IVA Squamous Cell Carcinoma of the Larynx|Stage IVA Oral Cavity Squamous Cell Carcinoma|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVA Verrucous Carcinoma of the Larynx|Stage IVA Verrucous Carcinoma of the Oral Cavity|Stage IVB Salivary Gland Cancer|Stage IVB Squamous Cell Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVB Verrucous Carcinoma of the Larynx|Stage IVB Verrucous Carcinoma of the Oral Cavity|Stage IVC Salivary Gland Cancer|Stage IVC Squamous Cell Carcinoma of the Larynx|Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Oropharynx|Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVC Verrucous Carcinoma of the Larynx|Stage IVC Verrucous Carcinoma of the Oral Cavity|Tongue Cancer|Untreated Metastatic Squamous Neck Cancer With Occult Primary NCT02035527
A Study to Estimate Safety and Efficacy of Sorafenib (BAY43-9006) in the Treatment of Hepatocellular Carcinoma Completed Carcinoma, Hepatocellular NCT00044512
Sorafenib in First-line Treatment of Advanced B Child Hepatocellular Carcinoma Terminated Advanced Adult Hepatocellular Carcinoma NCT01405573
Effect of Adjuvant Therapy by Sorafenib, Oxaliplatin and S-1 Withdrawn Hepatocellular Carcinoma NCT02129322
Sorafenib Tosylate Following a Liver Transplant in Treating Patients With Liver Cancer Active, not recruiting Adult Primary Hepatocellular Carcinoma|Localized Resectable Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer NCT01624285
Phase I Study of Perifosine + Sorafenib for Patients With Advanced Cancers Completed Renal Cancer|Tumors NCT00398814
Chinese Herbal Formulation PHY906 and Sorafenib Tosylate in Treating Patients With Advanced Liver Cancer Active, not recruiting Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Advanced Adult Hepatocellular Carcinoma|BCLC Stage B Adult Hepatocellular Carcinoma|BCLC Stage C Adult Hepatocellular Carcinoma NCT01666756
Study of Sorafenib and Docetaxel in Metastatic Prostate Cancer Completed Prostate Cancer NCT00619996
Sorafenib and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer Completed Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IV Colon Cancer|Stage IV Rectal Cancer NCT00826540
Assessing BAY86-9766 Plus Sorafenib for the Treatment of Liver Cancer. Completed Carcinoma, Hepatocellular NCT01204177
Cixutumumab and Sorafenib Tosylate in Treating Patients With Advanced Liver Cancer Completed Adult Hepatocellular Carcinoma|Advanced Adult Hepatocellular Carcinoma|Localized Non-Resectable Adult Liver Carcinoma|Recurrent Adult Liver Carcinoma NCT01008566
Dose Escalation Trial of Neoadjuvant Sorafenib and Concurrent Sorafenib, Cisplatin and Radiation in Locally Advanced Squamous Cell Carcinomas of the Head and Neck (SCCHN) Withdrawn Locally Advanced Squamous Cell Carcinomas of the Head and Neck (SCCHN) NCT00627835
Analysis of the Role of Hepatocyte SLAMF3 Receptor and Drug Resistance Proteins (MDR) in Resistance to Treatment With Sorafenib in CHC Patients Withdrawn Hepatocyte Receptor|Hepatocellular Carcinoma NCT03113604
A Study of Mapatumumab in Combination With Sorafenib in Subjects With Advanced Hepatocellular Carcinoma Completed Hepatocellular Carcinoma NCT00712855
Sorafenib for Residue Disease After Resection With Curative Intent Completed Carcinoma, Hepatocellular NCT01751763
A Safety, Tolerability, and Pharmacokinetics Study of Onartuzumab as Single Agent or in Combination With Sorafenib in Participants With Advanced Hepatocellular Carcinoma Completed Carcinoma, Hepatocellular NCT01897038
Comparison Study of Sorafenib and 5-fluorouracil/Mitomycin for Metastatic Hepatocellular Carcinoma Terminated Carcinoma, Hepatocellular NCT01171482
Nexavar® Versus Placebo in Locally Advanced/Metastatic RAI-Refractory Differentiated Thyroid Cancer Completed Thyroid Neoplasms NCT00984282
Sorafenib in Treating Patients With Recurrent Non-Hodgkin's Lymphoma Completed Anaplastic Large Cell Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Mantle Cell Lymphoma NCT00278382
Phase II Sorafenib With Radiation and Temozolomide in Newly Diagnosed Glioblastoma or Gliosarcoma Withdrawn Glioblastoma|Gliosarcoma NCT02599090
Hepatic Arterial Infusion of Oxaliplatin, Fluorouracil/Leucovorin Versus Sorafenib in Advanced Hepatocellular Carcinoma Recruiting Liver Cancer|Hepatic Carcinoma NCT03164382
HAIC Plus Lenvatinib vs HAIC Plus Sorafenib for Advanced HCC Recruiting Hepatocellular Carcinoma NCT03775395
Sorafenib Tosylate and Stereotactic Radiosurgery in Treating Patients With Brain Metastases Completed Tumors Metastatic to Brain NCT01276210
Sorafenib and LBH589 in Hepatocellular Carcinoma (HCC) Unknown status Hepatocellular Carcinoma NCT00823290
Breast Cancer Study: Paclitaxel Versus Paclitaxel Plus Sorafenib in Second- or Third-line Treatment Completed Metastatic Breast Cancer NCT01320111
Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma Completed Adult Angiosarcoma|Adult Epithelioid Sarcoma|Adult Leiomyosarcoma|Adult Malignant Fibrous Histiocytoma|Adult Neurofibrosarcoma|Adult Synovial Sarcoma|Ovarian Sarcoma|Recurrent Adult Soft Tissue Sarcoma|Recurrent Uterine Sarcoma|Stage III Adult Soft Tissue Sarcoma|Stage III Uterine Sarcoma|Stage IV Adult Soft Tissue Sarcoma|Stage IV Uterine Sarcoma|Uterine Carcinosarcoma|Uterine Leiomyosarcoma NCT00245102
Study in Patients With Advanced Non-Small Cell Lung Cancer Treated With Pemetrexed and Carboplatin Plus or Minus Sorafenib Terminated Carcinoma, Non-Small-Cell Lung NCT00473486
Resminostat (YHI-1001) in Combination With Sorafenib in Asian Patients With Advanced Hepatocellular Carcinoma (HCC) Completed Hepatocellular Carcinoma NCT02400788
Sorafenib in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed By Surgery Completed Stage III Melanoma|Stage IV Melanoma NCT00119249
Sorafenib Tosylate in Treating Patients With Malignant Mesothelioma. Completed Epithelial Mesothelioma|Recurrent Malignant Mesothelioma|Sarcomatous Mesothelioma|Stage IA Malignant Mesothelioma|Stage IB Malignant Mesothelioma|Stage II Malignant Mesothelioma|Stage III Malignant Mesothelioma|Stage IV Malignant Mesothelioma NCT00107432
Sorafenib in Combination With Carboplatin and Paclitaxel in Treating Participants With Metastatic or Recurrent Head and Neck Squamous Cell Cancer Active, not recruiting Metastatic Head and Neck Squamous Cell Carcinoma|Metastatic Squamous Cell Carcinoma of the Hypopharynx|Metastatic Squamous Cell Carcinoma of the Larynx|Metastatic Squamous Cell Carcinoma of the Oral Cavity|Metastatic Squamous Cell Carcinoma of the Oropharynx|Recurrent Head and Neck Squamous Cell Carcinoma|Recurrent Hypopharyngeal Squamous Cell Carcinoma|Recurrent Laryngeal Squamous Cell Carcinoma|Recurrent Oral Cavity Squamous Cell Carcinoma|Recurrent Oropharyngeal Squamous Cell Carcinoma NCT00494182
Third Line TKI After 2 TKIs in Patients With mRCC (Tokio Study) Terminated Renal Cancer Cell NCT03456401
Phase II Combination of Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma Active, not recruiting Hepatocellular Carcinoma NCT01687673
A Multicenter, Open-Label, Phase 3 Trial to Compare the Efficacy and Safety of Lenvatinib (E7080) Versus Sorafenib in First-line Treatment of Participants With Unresectable Hepatocellular Carcinoma Active, not recruiting Hepatocellular Carcinoma (HCC) NCT01761266
Sorafenib With TACE to Treat Hepatocellular Carcinoma Completed Hepatocellular Carcinoma NCT00478374
Drug Monitoring of Sorafenib in Patients With Advanced Hepatocellular Carcinoma Unknown status Hepatocellular Cancer NCT01078311
Sorafenib in Treating Patients With Advanced or Metastatic Cancer of the Urinary Tract Completed Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter|Recurrent Bladder Cancer|Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter|Regional Transitional Cell Cancer of the Renal Pelvis and Ureter|Stage III Bladder Cancer|Stage IV Bladder Cancer|Transitional Cell Carcinoma of the Bladder NCT00112671
Sorafenib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Chronic Myelogenous Leukemia Completed Adult Acute Basophilic Leukemia|Adult Acute Eosinophilic Leukemia|Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With t(15 NCT00131989
Sorafenib + Topotecan for Platinum-Resistant Recurrent Ovarian Cancer Terminated Ovarian Cancer NCT00526799
Study Combining Imatinib Mesylate (Gleevec) With Sorafenib in Patients With Androgen-independent Prostate Cancer (AIPC) Completed Prostate Cancer NCT00424385
Trial of Transcatheter Arterial Chemoembolization (TACE) With Sorafenib for Locally Advanced Hepatocellular Carcinoma (HCC) Unknown status Hepatocellular Carcinoma NCT01170104
A Phase II, Multi-Center, Open-Label, Uncontrolled Study to Evaluate the Efficacy and Safety of Sorafenib Given Daily in Combination With Repeated 21-Day Cycles of Dacarbazine (DTIC) Chemotherapy in Subjects With Advanced Metastatic Melanoma Completed Melanoma NCT00492297
Contribution of the Perfusion Scanner in the Prediction of the Tumor Control of Patients With Hepatocellular Carcinoma Treated With Sorafenib. Recruiting Hepatocellular Carcinoma|Perfusion Scanner NCT03140332
Sorafenib and Anastrozole in Treating Postmenopausal Women With Metastatic Breast Cancer Completed Recurrent Breast Cancer|Stage IV Breast Cancer NCT00217399
Nexavar-Tarceva Combination Therapy for First Line Treatment of Patients Diagnosed With Hepatocellular Carcinoma Completed Carcinoma, Hepatocellular NCT00901901
BAY 43-9006 in Previously Untreated Patients With Non-Small Cell Lung Cancer (NSCLC) Completed Lung Cancer NCT00533585
BAY 43-9006 (Sorafenib) to Treat Patients With Kaposi's Sarcoma Terminated Kaposi's Sarcoma|HHV-8|KSHV NCT00287495
Sorafenib in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer Completed Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer NCT00098540
Bevacizumab and Sorafenib in Treating Patients With Recurrent Glioblastoma Multiforme Completed Brain and Central Nervous System Tumors NCT00621686
Panobinostat and Sorafenib in Treating Patients With Liver Cancer That is Metastatic and/or Cannot Be Removed by Surgery Terminated Liver Cancer NCT00873002
Phase 1 Study With Sorafenib and Sirolimus Completed Advanced Solid Tumor|Refractory to Standard Therapies NCT00509613
DEB-TACE Plus Lenvatinib or Sorafenib or PD-1 Inhibitor for Unresectable Hepatocellular Carcinoma Not yet recruiting Hepatocellular Carcinoma NCT04229355
S0420, Sorafenib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer Completed Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma|Recurrent Metastatic Squamous Neck Cancer With Occult Primary|Recurrent Salivary Gland Cancer|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Salivary Gland Squamous Cell Carcinoma|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IVA Salivary Gland Cancer|Stage IVA Squamous Cell Carcinoma of the Larynx|Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVA Verrucous Carcinoma of the Larynx|Stage IVA Verrucous Carcinoma of the Oral Cavity|Stage IVB Salivary Gland Cancer|Stage IVB Squamous Cell Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVB Verrucous Carcinoma of the Larynx|Stage IVB Verrucous Carcinoma of the Oral Cavity|Stage IVC Salivary Gland Cancer|Stage IVC Squamous Cell Carcinoma of the Larynx|Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Oropharynx|Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVC Verrucous Carcinoma of the Larynx|Stage IVC Verrucous Carcinoma of the Oral Cavity|Tongue Cancer|Untreated Metastatic Squamous Neck Cancer With Occult Primary NCT00096512
Sorafenib in Treating Patients With Refractory or Relapsed Acute Leukemia, Myelodysplastic Syndromes, or Blastic Phase Chronic Myelogenous Leukemia Completed Adult Acute Basophilic Leukemia|Adult Acute Eosinophilic Leukemia|Adult Acute Megakaryoblastic Leukemia|Adult Acute Monoblastic Leukemia|Adult Acute Monocytic Leukemia|Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22) NCT00217646
Study to Evaluate the Effects of Sorafenib if Combined With Chemotherapy (FOLFOX6 or FOLFIRI) in the Second-Line Treatment of Colorectal Cancer Terminated Colorectal Neoplasms NCT00889343
Investigating Patient Characteristics of Intermediate Stage Hepatocellular Carcinoma Patients Treated With Nexavar and Their Distribution to Different Treatment Groups as Well as Determining Effectiveness and Safety Completed Carcinoma, Hepatocellular NCT01908322
Phase III Trial Comparing Capecitabine in Combination With Sorafenib or Placebo in the Treatment of Locally Advanced or Metastatic HER2-Negative Breast Cancer Completed Breast Cancer NCT01234337
Study of Sorafenib and Infusional 5-Fluorouracil in Advanced Hepatocellular Carcinoma (HCC) Completed Hepatocellular Carcinoma NCT00619541
Study Comparing Association Between Sorafenib and Interleukin-2 (IL-2) Versus Sorafenib in 1st Line Therapy in Advanced (Adv) Renal Cell Carcinoma (RCC) Completed Metastatic Disease|Renal Cell Carcinoma NCT00609401
Sorafenib in Treating Patients With Advanced Solid Tumors Terminated Unspecified Adult Solid Tumor, Protocol Specific NCT00436579
Sorafenib Tosylate in Treating Younger Patients With Relapsed or Refractory Rhabdomyosarcoma, Wilms Tumor, Liver Cancer, or Thyroid Cancer Completed Childhood Hepatocellular Carcinoma|Papillary Thyroid Cancer|Previously Treated Childhood Rhabdomyosarcoma|Recurrent Childhood Liver Cancer|Recurrent Childhood Rhabdomyosarcoma|Recurrent Thyroid Cancer|Recurrent Wilms Tumor and Other Childhood Kidney Tumors NCT01502410
Phase I-II to Evaluate Efficacy/Safety of Sorafenib+Gemcitabine+Radiotherapy in Locally Advanced Pancreatic Carcinoma Completed Pancreatic Cancer NCT00789763
Gemcitabine and Cisplatin Plus Sorafenib in Patients With Advanced Biliary Tract Carcinomas Naive to Systemic Therapy Completed Extrahepatic Bile Duct Cancer|Gallbladder Cancer NCT00919061
Sorafenib Tosylate With or Without Doxorubicin Hydrochloride in Treating Patients With Locally Advanced or Metastatic Liver Cancer Active, not recruiting Advanced Adult Hepatocellular Carcinoma|Recurrent Hepatocellular Carcinoma|Stage III Hepatocellular Carcinoma AJCC v7|Stage IIIA Hepatocellular Carcinoma AJCC v7|Stage IIIB Hepatocellular Carcinoma AJCC v7|Stage IIIC Hepatocellular Carcinoma AJCC v7|Stage IV Hepatocellular Carcinoma AJCC v7|Stage IVA Hepatocellular Carcinoma AJCC v7|Stage IVB Hepatocellular Carcinoma AJCC v7|Unresectable Hepatocellular Carcinoma NCT01015833
North Carolina Brevard United States|Novant Health Presbyterian Medical Center Asheville
Study to Evaluate the Effect of Renal Function on the Single-Dose Pharmacokinetics of BAY 43-9006 Completed Kidney Diseases NCT00119639
BAY 43-9006 Plus Cetuximab to Treat Colorectal Cancer Completed Metastatic Colorectal Cancer NCT00326495
Sorafenib and Erlotinib in Treating Patients With Metastatic or Unresectable Solid Tumors Completed Unspecified Adult Solid Tumor, Protocol Specific NCT00126620
BAY43-9006 - Phase II Study in Non-Small Cell Lung Carcinoma (NSCLC) Completed Cancer|Carcinoma, Non-Small Cell Lung NCT00101413
Sorafenib and Temsirolimus in Treating Patients With Unresectable or Metastatic Solid Tumors Completed Unspecified Adult Solid Tumor, Protocol Specific NCT00255658
Multicentre, Dose Finding, Ph II,CP-4055 in Comb. With Sorafenib - Patients With Metastatic Malignant Melanoma Completed Malignant Melanoma NCT00498836
Study to Determine the Safety, Maximum Tolerated Dose, Pharmacokinetics of Sorafenib (BAY43-9006) Completed Carcinoma NCT00941863
Biomarker Analysis in Sorafenib Treated Hepatocellular Carcinoma Patients Completed Hepatocellular Carcinoma NCT01481805
Phase I/II Trial of RAD001 Plus Nexavar in Patients With Kidney Cancer Completed Carcinoma, Renal Cell NCT00448149
Sorafenib and Gemcitabine in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer Completed Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage II Pancreatic Cancer|Stage III Pancreatic Cancer|Stage IV Pancreatic Cancer NCT00095966
Study of Recombinant Interleukin 21 in Combination With Sorafenib for Metastatic Renal Cell Carcinoma Completed Carcinoma, Renal Cell NCT00389285
Sorafenib. ICORG 06-41, V4 Completed Esophageal Cancer|Gastric Cancer NCT01158287
HAIC Plus PD-1 Antibody vs HAIC Plus Sorafenib for Advanced HCC Withdrawn Hepatocellular Carcinoma NCT03780634
Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies Completed Acute Myeloid Leukemia NCT02270788
A Study to Evaluate SHR-1210 in Combination With Apatinib as First-Line Therapy in Patients With Advanced HCC Recruiting Locally Advanced or Metastatic and Unresectable HCC NCT03764293
Study of Modified FOLFOX6 Plus or Minus Sorafenib in Stage IV Metastatic Colorectal Carcinoma (mCRC) Subjects Completed Metastatic Colorectal Cancer NCT00865709
Sorafenib in Treating Patients With Advanced or Recurrent Uterine Cancer Completed Recurrent Uterine Sarcoma|Stage III Uterine Sarcoma|Stage IV Uterine Sarcoma|Uterine Carcinosarcoma NCT00238121
Radiation Therapy and Temozolomide Followed by Temozolomide Plus Sorafenib for Glioblastoma Multiforme Completed Glioblastoma Multiforme NCT00544817
A Study of ONCO-DOX in Locally Advanced Hepatocellular Carcinoma Terminated Hepatocellular Carcinoma|Hepatoma|Liver Cell Carcinoma NCT02460991
Study of Oxaliplatin and Sorafenib Combination to Treat Gastric Cancer Relapsed After a Cisplatin Based Treatment Completed Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (Relapsed After a Cisplatin Based Treatment) NCT01262482
Sorafenib Tosylate in Treating Patients With Progressive Metastatic Neuroendocrine Tumors Completed Gastrinoma|Glucagonoma|Insulinoma|Metastatic Gastrointestinal Carcinoid Tumor|Neuroendocrine Tumor|Pancreatic Polypeptide Tumor|Recurrent Gastrointestinal Carcinoid Tumor|Recurrent Islet Cell Carcinoma|Somatostatinoma|WDHA Syndrome NCT00131911
Sorafenib in Treating Patients With Kidney Cancer That Has Spread to the Brain Completed Kidney Cancer|Metastatic Cancer NCT00301847
18F-FDG PET in HCC Patients Candidate to Treatment With Sorafenib Recruiting HCC NCT02977754
Efficacy and Tolerability of ABT-869 Versus Sorafenib in Advanced Hepatocellular Carcinoma (HCC) Terminated Hepatocellular Carcinoma Non-resectable|Hepatocellular Carcinoma Recurrent|Carcinoma, Hepatocellular|Liver Diseases|Neoplasms by Histologic Type|Digestive System Neoplasms|Carcinoma|Liver Neoplasms|Neoplasms|Neoplasms by Site|Digestive System Diseases|Adenocarcinoma|Neoplasms, Glandular and Epithelial NCT01009593
Sorafenib, Docetaxel, and Cisplatin in Treating Patients With Metastatic or Advanced Gastric or Gastroesophageal Junction Cancer Completed Adenocarcinoma of the Gastroesophageal Junction|Metastatic Gastric Cancer|Advanced Unresectable Gastric Cancer NCT00253370
A Study of LY2157299 in Participants With Unresectable Hepatocellular Cancer (HCC) Completed Hepatocellular Carcinoma NCT02240433
Sorafenib in Elderly mRCC Completed Carcinoma, Renal Cell NCT01728948
Sorafenib Tosylate, Bevacizumab, Irinotecan Hydrochloride, Leucovorin Calcium, and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer Completed Recurrent Colon Carcinoma|Recurrent Rectal Carcinoma|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer NCT01383343
Sorafenib in Urothelium Cancer of Bladder Terminated Bladder Cancer NCT01215266
Oxaliplatin and Capecitabine on Top of Sorafenib Versus Sorafenib Alone in Advanced Hepatocellular Carcinoma Patients Withdrawn Hepatic Neoplasm Malignant NCT01245582
Long-term Extension From RCC Phase II (11515) Completed Carcinoma, Renal Cell NCT00586495
Sorafenib and Erlotinib in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery Completed Pancreatic Cancer NCT00837876
Sorafenib With Either Temsirolimus or Tipifarnib in Treating Patients With Stage IV Malignant Melanoma That Cannot Be Removed By Surgery Completed Recurrent Melanoma|Stage IV Melanoma NCT00281957
Sorafenib Tosylate and Temsirolimus in Treating Patients With Recurrent Glioblastoma Completed Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Neoplasm NCT00329719
Sorafenib Plus Tegafur/Uracil (UFUR®) for Hepatocellular Carcinoma (HCC) Completed Hepatocellular Carcinoma NCT00464919
Study to Compare Pharmacokinetic Property of SYO-1644 Tab. and Nexavar Tab. in Healthy Male Volunteers Completed Healthy, Male NCT03674060
Sorafenib Tosylate, Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With High-Risk Stage IIB-IV Soft Tissue Sarcoma Active, not recruiting Pleomorphic Rhabdomyosarcoma|Stage IIB Adult Soft Tissue Sarcoma AJCC v7|Stage III Adult Soft Tissue Sarcoma AJCC v7|Stage IV Adult Soft Tissue Sarcoma AJCC v7 NCT02050919
Combination of Transcatheter Arterial Chemoembolization (TACE) and Sorafenib for Patients With Unresectable Hepatocellular Carcinoma (HCC) Completed Carcinoma, Hepatocellular NCT00919009
Global Investigation of Therapeutic Decisions in Hepatocellular Carcinoma and of Its Treatment With Sorafenib Completed Carcinoma, Hepatocellular NCT00812175
A Trial Comparing Safety and Efficacy of Carboplatin and Paclitaxel Plus or Minus Sorafenib (BAY43-9006) in Chemonaive Patients With Stage IIIB-IV Non-Small Cell Lung Cancer (NSCLC) Terminated Carcinoma, Non-Small-Cell Lung NCT00558636
Study Multicentre Evaluating the Effectiveness and Toxicity Sorafenib (Nexavar®) in Adult Patients With Uveal Melanoma and Metastatic Dissemination Completed Uveal Melanoma NCT02517736
Sorafenib, Cetuximab, and Irinotecan in Treating Patients With Advanced or Metastatic Colorectal Cancer Completed Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage III Colon Cancer|Stage III Rectal Cancer|Stage IV Colon Cancer|Stage IV Rectal Cancer NCT00134069
Effect of Sorafenib or Regorafenib on P63 Expression and Keratinocyte Differentiation in Human Skin Terminated Renal Cell Carcinoma|Hepatocellular Carcinoma|Colorectal Carcinoma NCT01466504
Comparison of Nexavar/Placebo as Maintenance Therapy for Patients With Advanced Ovarian or Primary Peritoneal Cancer Completed Ovarian Neoplasms NCT00791778
Sorafenib and Low Dose Cytarabine in Older Patients With Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome Completed Leukemia|Myelodysplastic Syndromes NCT00516828
Sorafenib Combined With Cisplatin and Etoposide or Carboplatin and Pemetrexed in Treating Patients With Metastatic Solid Tumors Completed Unspecified Adult Solid Tumor, Protocol Specific NCT00573690
Sorafenib Tosylate With or Without Recombinant Interferon Alfa-2b in Treating Patients With Metastatic Kidney Cancer Completed Clear Cell Renal Cell Carcinoma|Recurrent Renal Cell Carcinoma|Stage IV Renal Cell Cancer NCT00126594
Sorafenib With or Without Gemcitabine in Treating Patients With Metastatic Pancreatic Cancer Completed Stage IV Pancreatic Cancer NCT00114244
Sorafenib, Busulfan and Fludarabine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant Recruiting Allogeneic Hematopoietic Stem Cell Transplant Recipient|Donor|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia NCT03247088
A Study of Dovitinib Versus Sorafenib in Adult Patients With Hepatocellular Carcinoma (HCC) as a First Line Treatment Completed Hepatocellular Carcinoma NCT01232296
Sorafenib Tosylate and Gemcitabine Hydrochloride in Treating Patients With Recurrent Epithelial Ovarian Cancer Completed Recurrent Ovarian Epithelial Cancer|Recurrent Primary Peritoneal Cavity Cancer NCT00096395
Sorafenib Gastric Cancer Asian Phase I Study Completed Gastric Cancer NCT00663741
Sorafenib, Carboplatin, and Paclitaxel in Treating Patients With Stage IV Melanoma of the Eye Completed Ciliary Body and Choroid Melanoma, Medium/Large Size|Extraocular Extension Melanoma|Iris Melanoma|Metastatic Intraocular Melanoma|Recurrent Intraocular Melanoma NCT00329641
Sorafenib Tosylate and Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia Active, not recruiting Acute Myeloid Leukemia With FLT3/ITD Mutation|Acute Myeloid Leukemia With Inv(16)(p13.1q22) or t(16 NCT01253070
Sorafenib in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer in at Least the Second Remission Terminated Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer NCT00522301
Efficacy Evaluation of TheraSphere to Treat Inoperable Liver Cancer With Blockage of the Portal Vein Terminated Hepatocellular Carcinoma NCT01887717
Treatment Protocol for the Use of Sorafenib in Patients With Advanced Renal Cell Carcinoma Completed Carcinoma, Renal Cell NCT00111020
Role of Positron Emission Tomography in the Evaluation of Response to Sorafenib in Advanced Hepatocellular Carcinoma Completed Hepatocellular Carcinoma NCT01157013
A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and Effective Completed Metastatic Hepatocellular Carcinoma|Advanced Liver Cancer NCT01754987
HAIC Plus Sorafenib Versus TACE Plus Sorafenibfor Advanced HCC Recruiting Hepatocellular Carcinoma NCT02856126
HAIC of FOLFOX Plus Sorafenib vs HAIC of FOLFIRINOX Plus Sorafenib for Advcanced HCC Recruiting Hepatocellular Carcinoma NCT03812783
Study in Asia of the Combination of TACE With Sorafenib in HCC Patients Unknown status Hepatocellular Carcinoma NCT00990860
Sorafenib and Interferon Alfa in Treating Patients With Locally Advanced or Metastatic Kidney Cancer Terminated Clear Cell Renal Cell Carcinoma|Papillary Renal Cell Carcinoma|Recurrent Renal Cell Cancer|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer NCT00098618
Sorafenib and High-Dose Carboplatin, Paclitaxel, and External-Beam Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer Withdrawn Lung Cancer NCT00547443
Phase I/II Comparison of Efficacy and Safety of BIBF 1120 and Sorafenib in Patients With Advanced Hepatocellular Carcinoma Completed Carcinoma, Hepatocellular NCT01004003
Extension Program for Bay 43-9006 Completed Neoplasm|Metastasis NCT00657254
17-AAG and Sorafenib in Treating Patients With Unresectable or Metastatic Solid Tumors Completed Unspecified Adult Solid Tumor, Protocol Specific NCT00121264
Study of GC33 and Sorafenib in Combination in Advanced or Metastatic Liver Cancer (Hepatocellular Carcinoma) Completed Hepatocellular Carcinoma NCT00976170
Sorafenib Tosylate in Treating Patients With Liver Cancer That Can Be Removed by Surgery Unknown status Liver Cancer NCT01182272
A Study of the Effectiveness and Safety of AMG 386 and Sorafenib to Treat Advanced or Inoperable Hepatocellular Cancer Completed Advanced Hepatocellular Carcinoma|Inoperable Hepatocellular Carcinoma NCT00872014
Sorafenib Tosylate and Everolimus in Treating Patients With Advanced Solid Tumors and Metastatic Pancreatic Cancer That Does Not Respond to Gemcitabine Hydrochloride Completed Acinar Cell Adenocarcinoma of the Pancreas|Duct Cell Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage IV Pancreatic Cancer|Unspecified Adult Solid Tumor, Protocol Specific NCT00981162
Sorafenib, Cisplatin, and Etoposide in Treating Patients With Extensive-Stage Small Cell Lung Cancer Terminated Lung Cancer NCT00726986
Bevacizumab and Sorafenib in Treating Patients With Unresectable Stage III or Stage IV Malignant Melanoma Completed Recurrent Melanoma|Stage III Skin Melanoma|Stage IV Skin Melanoma NCT00387751
Sorafenib in Previously Treated Malignant Mesothelioma Unknown status Mesothelioma NCT00794859
CO07204-Phase I/II of Oxaliplatin, Capecitabine & Sorafenib for Advanced Pancreatic & Biliary Carcinoma Completed Pancreatic Neoplasms|Bile Duct Neoplasms NCT00634751
Sorafenib, Gemcitabine, and Capecitabine in Treating Patients With Unresectable and/or Metastatic Kidney Cancer Completed Recurrent Renal Cell Carcinoma|Stage III Renal Cell Cancer AJCC v7|Stage IV Renal Cell Cancer AJCC v7 NCT00121251
Bevacizumab and Sorafenib as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Liver Cancer Completed Liver Cancer NCT00867321
Sorafenib and Interferon Alfa in Treating Patients With Metastatic or Unresectable Kidney Cancer Completed Clear Cell Renal Cell Carcinoma|Recurrent Renal Cell Cancer|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer NCT00101114
S0514 Sorafenib in Treating Patients With Unresectable or Metastatic Gallbladder Cancer or Cholangiocarcinoma Completed Adenocarcinoma of the Extrahepatic Bile Duct|Adenocarcinoma of the Gallbladder|Adenocarcinoma With Squamous Metaplasia of the Gallbladder|Cholangiocarcinoma of the Extrahepatic Bile Duct|Cholangiocarcinoma of the Gallbladder|Recurrent Extrahepatic Bile Duct Cancer|Recurrent Gallbladder Cancer|Squamous Cell Carcinoma of the Gallbladder|Unresectable Extrahepatic Bile Duct Cancer|Unresectable Gallbladder Cancer NCT00238212
Gemcitabine and Sorafenib in Advanced Biliary Tract Cancer (GEMSO) Completed Adenocarcinoma NCT00661830
Bevacizumab and Erlotinib or Sorafenib as First-Line Therapy in Treating Patients With Advanced Liver Cancer Completed Liver Cancer NCT00881751
BAY43-9006 (Sorafenib) Versus Interferon Alpha-2a in Patients With Unresectable and/or Metastatic Renal Cell Carcinoma Completed Carcinoma, Renal Cell NCT00117637
Phase III Study of BAY43-9006 in Patients With Advanced Hepatocellular Carcinoma (HCC) Treated After Transcatheter Arterial Chemoembolization (TACE) Completed Carcinoma, Hepatocellular NCT00494299
Phase I Trial of Bevacizumab and Temsirolimus in Combination With 1) Carboplatin, 2) Paclitaxel, 3) Sorafenib for the Treatment of Advanced Cancer Active, not recruiting Advanced Cancer NCT01187199
Sorafenib in Treating Patients With Angiosarcoma That is Locally Advanced, Metastatic, or Unable to Be Removed by Surgery Unknown status Sarcoma NCT00874874
Drug Interaction Study of Sorafenib and Rapamycin in Advanced Malignancies Completed Advanced Solid Tumor NCT00449280
Assess the Safety and Activity of Combined MG005 and Sorafenib (NEXAVAR®) Treatment With Solid Tumor Recruiting Solid Tumor NCT03406364
Study to Observe Safety and Efficacy of Nexavar in Treatment of Kidney Cancer Withdrawn Carcinoma, Renal Cell NCT01353794
Italian Study Of Validation Of Angiogenesis Polymorphisms In HCC Patients Treated With Sorafenib Recruiting Hepatocellular Carcinoma NCT02786342
Sorafenib in Treating Patients With Metastatic or Recurrent Prostate Cancer Completed Prostate Cancer NCT00093457
Neoadjuvant Chemotherapy Followed by Radiation Therapy and Gemcitabine/Sorafenib/Vorinostat in Pancreatic Cancer Recruiting Pancreatic Adenocarcinoma|Stage IA Pancreatic Cancer|Stage IB Pancreatic Cancer|Stage IIA Pancreatic Cancer|Stage IIB Pancreatic Cancer|Stage III Pancreatic Cancer|Recurrent Pancreatic Carcinoma NCT02349867
A Study to Evaluate the Efficacy and Safety of Sintilimab in Combination With IBI305 (Anti-VEGF Monoclonal Antibody) Compared to Sorafenib as the First-Line Treatment for Advanced Hepatocellular Carcinoma. Recruiting Hepatocellular Carcinoma NCT03794440
Sorafenib, Epirubicin, Ifosfamide, and Radiation Therapy Followed By Surgery in Treating Patients With High-Risk Stage II or Stage III Soft Tissue Sarcoma Completed Sarcoma NCT00822848
Sunitinib Malate or Sorafenib Tosylate in Treating Patients With Kidney Cancer That Was Removed By Surgery Completed Clear Cell Renal Cell Carcinoma|Stage I Renal Cell Cancer AJCC v6 and v7|Stage II Renal Cell Cancer AJCC v7|Stage III Renal Cell Cancer AJCC v7 NCT00326898
United States|Etzell Fergus Falls United States|Lake Region Healthcare Corporation-Cancer Care Minnesota
United States|HSHS Sacred Heart Hospital Wisconsin Eau Claire Wisconsin
Community Oncology Setting Disease Outcomes of Sorafenib (Nexavar) Use in Advanced Renal Cell Carcinoma Completed Renal Cell Carcinoma NCT00876382
A Phase III Randomized, Double-blind, Placebo Controlled Trial Comparing the Efficacy of Gemcitabine, Cisplatin and Sorafenib to Gemcitabine, Cisplatin and Placebo in First-Line Treatment of Patients With Stage IIIb With Effusion and Stage IV Non-Small Cell Lung Cancer (NSCLC) Completed Carcinoma, Non-Small-Cell Lung NCT00449033
Study of Gemcitabine and Erlotinib Plus Sorafenib (GES) in Metastatic Pancreatic Cancer Completed Pancreatic Cancer NCT00696696
Cisplatin or Carboplatin and Sorafenib in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery Completed Liver Cancer NCT00875615
Pemetrexed Disodium With or Without Sorafenib as Second-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer Completed Lung Cancer NCT00454194
Study of Cabozantinib in Combination With Atezolizumab Versus Sorafenib in Subjects With Advanced HCC Who Have Not Received Previous Systemic Anticancer Therapy Recruiting Hepatocellular Carcinoma NCT03755791
Study of Nexavar (Sorafenib, BAY 43-9006) in Patients With Advanced Refractory Cancer Completed Carcinoma, Renal Cell NCT00079612
MRI Study of BAY 43-9006 in Metastatic Renal Cell Carcinoma Completed Metastatic Renal Cell Carcinoma NCT00606866
Sorafenib Combined With Erlotinib, Tipifarnib, or Temsirolimus in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma Completed Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor NCT00335764
Phase IV Randomization to On-Going Treatment to Evaluate Sustained Sorafenib Terminated Carcinoma, Renal Cell NCT00352859
Sorafenib, Lenalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma Terminated Multiple Myeloma and Plasma Cell Neoplasm NCT00687674
A Phase II Study Of Abraxane and Nexavar in the First-Line Treatment of Locally Advanced or Metastatic Breast Cancer Terminated Breast Cancer NCT00607438
Sorafenib in Treating Patients With Metastatic Breast Cancer Completed Male Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer NCT00096434
Nexavar as First Targeted Therapy in Patients With Advanced Renal Cell Carcinoma Completed Carcinoma, Renal Cell NCT01508364
Temozolomide and Sorafenib in Treating Patients With Metastatic or Unresectable Melanoma Unknown status Melanoma (Skin) NCT00602576
Mitoxantrone, Prednisone Plus Sorafenib in Taxane-Refractory Metastatic Hormone Refractory Prostate Cancer (HRPC) Terminated Metastatic Prostate Cancer NCT00452387
SECOX as Neoadjuvant Therapy in Patients With Locally Advanced HCC Recruiting Hepatocellular Carcinoma NCT03578874
Adjuvant Doxorubicin/Cyclophosphamide and Paclitaxel Plus Sorafenib Breast Cancer Completed Breast Cancer NCT00544167
Dose Escalation of Sorafenib in Patients With Advanced Hepatocellular Carcinoma (HCC) Completed Carcinoma, Hepatocellular NCT00490685
Erlotinib and Sorafenib in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme Completed Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor NCT00445588
Sorafenib With or Without Gemcitabine and Oxaliplatin in Treating Patients With Locally Advanced, Unresectable, or Metastatic Liver Cancer Completed Liver Cancer NCT00941967
Sorafenib Tosylate in Treating Patients With Locally Advanced, Metastatic, or Locally Recurrent Thyroid Cancer Terminated Anaplastic Thyroid Cancer|Insular Thyroid Cancer|Recurrent Thyroid Cancer|Stage III Follicular Thyroid Cancer|Stage III Papillary Thyroid Cancer|Stage IV Follicular Thyroid Cancer|Stage IV Papillary Thyroid Cancer NCT00095693
Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery Active, not recruiting Hepatocellular Carcinoma|Unresectable Hepatocellular Carcinoma NCT01004978
Palliative Treatments for Patients With Advanced Hepatocellular Carcinoma (HCC) Completed Hepatectomy|Hepatocellular Carcinoma|Sorafenib NCT01409499
Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent Cetuximab Completed Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma|Recurrent Metastatic Squamous Neck Cancer With Occult Primary|Recurrent Salivary Gland Cancer|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Salivary Gland Squamous Cell Carcinoma|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IVA Salivary Gland Cancer|Stage IVA Squamous Cell Carcinoma of the Larynx|Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVA Verrucous Carcinoma of the Larynx|Stage IVA Verrucous Carcinoma of the Oral Cavity|Stage IVB Salivary Gland Cancer|Stage IVB Squamous Cell Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVB Verrucous Carcinoma of the Larynx|Stage IVB Verrucous Carcinoma of the Oral Cavity|Stage IVC Salivary Gland Cancer|Stage IVC Squamous Cell Carcinoma of the Larynx|Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Oropharynx|Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVC Verrucous Carcinoma of the Larynx|Stage IVC Verrucous Carcinoma of the Oral Cavity|Tongue Cancer|Untreated Metastatic Squamous Neck Cancer With Occult Primary NCT00939627
Clinical Trial on the Mixture of G, C and S in Treatment of Patients With RCC Completed Carcinoma, Renal Cell NCT00496301
The Phase III Study of Icaritin Versus Sorafenib in PD-L1 Positive Advanced Hepatocellular Carcinoma Subjects Unknown status Hepatocellular Carcinoma (HCC) NCT03236649
Efficacy and Safety of Donafenib in Patients With Advanced Hepatocellular Carcinoma Completed HCC NCT02645981
Residual Plasma Concentration of Sorafenib and Adverse Events in CHC Unknown status Advanced or Metastatic Hepatocellular Carcinoma NCT03340636
The Effect of Urea Cream on Sorafenib-associated Hand-Foot Skin Reaction Completed Hepatocellular Carcinoma NCT03212625
Temsirolimus Versus Sorafenib As Second-Line Therapy In Patients With Advanced RCC Who Have Failed First-Line Sunitinib Completed Renal Cell Carcinoma NCT00474786
Ph 1 Trial of ADI PEG 20 Plus Sorafenib to Treat Patients With Liver Cancer Completed Hepatocellular Carcinoma NCT02101593
Sorafenib in Treating Patients With Soft Tissue Sarcomas (Extremity Sarcoma Closed to Entry as of 5/30/07) Completed Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Metastatic Osteosarcoma|Recurrent Adult Soft Tissue Sarcoma|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Osteosarcoma|Stage I Adult Soft Tissue Sarcoma|Stage II Adult Soft Tissue Sarcoma|Stage III Adult Soft Tissue Sarcoma|Stage IV Adult Soft Tissue Sarcoma NCT00330421
HCC Patient Preferences in Japan Completed Hepatocellular Cancer NCT02616692
BAY43-9006 Phase II Study for Renal Cell Carcinoma Completed Carcinoma, Renal Cell NCT00661375
Cisplatin/Etoposide/Radiotherapy Followed by Consolidation Sorafenib for Inoperable Stage III Non-Small Cell Lung Cancer Terminated Non-Small Cell Lung Cancer NCT00417248
Evaluation of Cognitive Function of Patients With Sunitinib or Sorafenib Completed Metastatic Renal Cell Cancer|GIST NCT01246843
Filgrastim, Cladribine, Cytarabine, and Mitoxantrone With Sorafenib Tosylate in Treating Patients With Newly-Diagnosed, Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome Recruiting Acute Biphenotypic Leukemia|Acute Myeloid Leukemia|de Novo Myelodysplastic Syndrome|Myelodysplastic Syndrome|Myeloproliferative Neoplasm NCT02728050
An Open-Label, Non-Comparative, Phase III Study of the Raf-Kinase Inhibitor BAY 43-9006 as a Subsequent to First-Line Therapy in Patients With Advanced Renal Cell Carcinoma Completed Carcinoma, Renal Cell NCT00492986
Sorafenib in Treating Patients at Risk of Relapse After Undergoing Surgery to Remove Kidney Cancer Completed Kidney Cancer NCT00492258
Sorafenib and Docetaxel in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Previous Hormone Therapy Completed Prostate Cancer NCT00589420
A Phase II Trial OF Carboplatin, ABI-007 (Abraxane) And Sorafenib (BAY 43-9006) in Metastatic Melanoma Completed Malignant Melanoma NCT00483301
Combined Treatment of Sorafenib and Pegylated Interferon α2b in Stage IV Metastatic Melanoma Completed Melanoma NCT00623402
Carboplatin and Paclitaxel With or Without Sorafenib Tosylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery Completed Mucosal Melanoma|Recurrent Melanoma|Stage IIIA Skin Melanoma|Stage IIIB Skin Melanoma|Stage IIIC Skin Melanoma|Stage IV Skin Melanoma NCT00110019
Bevacizumab, Sorafenib Tosylate, and Temsirolimus in Treating Patients With Metastatic Kidney Cancer Completed Clear Cell Renal Cell Carcinoma|Recurrent Renal Cell Carcinoma|Stage IV Renal Cell Cancer AJCC v7 NCT00378703
Pennsylvania Scranton United States|Geisinger Medical Group Scranton
Sorafenib and Isolated Limb Infusion of Melphalan in Treating Patients With Stage III Melanoma of the Arm or Leg Completed Melanoma (Skin) NCT00565968
Sequential Study to Treat Renal Cell Carcinoma Completed Renal Cell Carcinoma NCT00732914
INSIGHT - Post Marketing Surveillance Completed Carcinoma, Hepatocellular NCT00792350
A Dose-Finding and Exploratory Study of RO5323441 in Combination With Sorafenib in Patients With Hepatocellular Carcinoma Completed Carcinoma, Hepatocellular NCT01308723
Sorafenib With or Without Paclitaxel and Carboplatin in Treating Patients With Recurrent Ovarian Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer Completed Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma NCT00096200
Sorafenib Tosylate and Gene Expression Analysis in Patients Undergoing Surgery For High-Risk Localized Prostate Cancer Completed Adenocarcinoma of the Prostate|Stage II Prostate Cancer|Stage III Prostate Cancer NCT00466752
Gemcitabine With or Without Sorafenib in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer Unknown status Pancreatic Cancer NCT00541021
Phase 2b Study of Taxol Plus Sorafenib or Placebo in Patients With Advanced Breast Cancer Active, not recruiting Breast Cancer NCT00499525
Sorafenib to Treat FLT3-ITD AML Recruiting Acute Myeloid Leukemia|FLT3-ITD Mutation NCT02156297
First Line Hepato Cellular Carcinoma (HCC) Completed Hepato Cellular Carcinoma (HCC) NCT00858871
Lenalidomide in Combination With Bevacizumab, Sorafenib, Temsirolimus, or 5-Fluorouracil, Leucovorin, Oxaliplatin (FOLFOX) Completed Advanced Cancers NCT01183663
Study of BAY43-9006 in Patients With Unresectable and/or Metastatic Renal Cell Cancer Completed Carcinoma, Renal Cell NCT00073307
Comparison of Brivanib and Best Supportive Care (BSC) With Placebo and BSC for Treatment of Liver Cancer in Asian Patients Who Have Failed Sorafenib Treatment Terminated Carcinoma, Hepatocellular NCT01108705
Patient Characteristics in Advanced Renal Cell Carcinoma and Daily Practice Treatment With Nexavar Completed Carcinoma, Renal Cell|Carcinoma, Renal Cell (Advanced) NCT00895674
Comparison of Brivanib and Best Supportive Care to Placebo for Treatment of Liver Cancer for Those Subjects Who Have Failed Sorafenib Treatment Completed Liver Cancer NCT00825955
A Phase 2b Study of Modified Vaccinia Virus to Treat Patients Advanced Liver Cancer Who Failed Sorafenib Completed Hepatocellular Carcinoma|Liver Cancer|HCC NCT01387555
Open Label Phase II Study of BAY 43-9006 in Chronic Myelogenous Leukemia (CML) Patients Resistant to Gleevec Completed Chronic Myelogenous Leukemia NCT00661180
Study on the Influence of Sunitinib and Sorafenib on Fatigue, QoL, Depression in Patients With Metastatic RCC or GIST Completed Renal Cell Cancer|Colorectal Cancer|GIST NCT00979329
A Study of BAY 43-9006 in Combination With Bicalutamide in Patients With Chemo-NaĂŻve Hormone Refractory Prostate Cancer Completed Adenocarcinoma of the Prostate NCT00430235
Sorafenib Tosylate and Chemoembolization in Treating Patients With Unresectable Liver Cancer Completed Hepatocellular Carcinoma|Liver Cancer|Localized Unresectable Liver Cancer NCT01042041
Treatment for Subjects With Unresectable Stage III or Stage IV Melanoma Completed Cancer|Melanoma NCT00110994
A Trial to Evaluate the Characteristics of Patients Treated for Advanced Renal Cell Carcinoma With Nexavar ® Completed Carcinoma, Renal Cell|Carcinoma, Renal Cell (Advanced) NCT00771147
A Study of IMC-A12 in Combination With Sorafenib in Participants With Advanced Cancer of the Liver Completed Hepatocellular Carcinoma NCT00906373
HAIC of FOLFOX vs. HAIC of OXA for Advanced HCC Unknown status Hepatocellular Carcinoma NCT03468231
BAY 43-9006 (Sorafenib) and Bevacizumab (Avastin) To Treat Solid Tumors Completed Neoplasms NCT00095459
Multimetabolic 18F-Fluorodeoxyglucose (FDG) and 18F-Fluorocholine (FCH) Positron Emission Tomography (PET) as an Early Predictive Factor of Overall Survival in Patients With Advanced Hepatocellular Carcinoma Treated With Sorafenib Recruiting Carcinoma, Hepatocellular NCT02847468
Sorafenib, Bevacizumab, and Oxaliplatin in Treating Patients With Metastatic Malignant Melanoma Unknown status Melanoma (Skin) NCT00538005
Trebananib With or Without Bevacizumab, Pazopanib Hydrochloride, Sorafenib Tosylate, or Sunitinib Malate in Treating Patients With Advanced Kidney Cancer Active, not recruiting Advanced Renal Cell Carcinoma|Stage III Renal Cell Cancer AJCC v7|Stage IV Renal Cell Cancer AJCC v7 NCT01664182
Stereotactic Body Radiotherapy (SBRT) and Sorafenib in Patients With Metastatic, Recurrent, or Unresectable Renal Cell Cancer (RCC) Terminated Renal Cell Carcinoma NCT00672178
Adjuvant Therapies for Patients With HCC and MVI Recruiting Hepatocellular Carcinoma NCT02436902
Biomarkers in Blood Samples From Patients With Refractory Non-Small Cell Lung Cancer Previously Treated With Sorafenib Tosylate Completed Lung Cancer NCT01124669
AMG 386, 20060159 Phase 2, RCC 1st Line in Combination With Sorafenib Completed Advanced Renal Cell Carcinoma NCT00467025
Sorafenib and Letrozole, Anastrozole, or Exemestane in Treating Postmenopausal Women With Estrogen Receptor-Positive and/or Progesterone Receptor-Positive Metastatic Breast Cancer Terminated Breast Cancer NCT00573755
Analysis of cfDNA in Patients With Hepatocarcinoma and Treated by Sorafenib or Regorafenib Recruiting Hepatocarcinoma NCT03956940
1st or 2nd Line MBC (Metastatic Breast Cancer) With Previous Avastin (Bevacizumab) Therapy Completed Breast Cancer NCT00493636
A Treatment Combination for Patients With Unresectable Stage III or Stage IV Melanoma Completed Melanoma NCT00111007
Dose Escalating Study With BAY43-9006 With Carboplatin, Paclitaxel and Bevacizumab in Untreated Stage IIIb Non-small Cell Lung Cancer (NSCLC) Completed Carcinoma, Non-Small-Cell Lung|Lung Cancer NCT01069328
Sorafenib, Tamoxifen, and Cisplatin in Treating Patients With High-Risk Stage III Melanoma Unknown status Melanoma (Skin) NCT00492505
To Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 386 When Used in Combination With AMG 706, Bevacizumab, Sorafenib, or Sunitinib. Completed Advanced Solid Tumors NCT00861419
Regulatory Post Marketing Surveillance Study on Nexavar® Completed Carcinoma, Hepatocellular|Carcinoma, Renal Cell NCT01012011
Sorafenib Tosylate and Chemoembolization With Doxorubicin Hydrochloride and Mitomycin in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery Completed Liver Cancer NCT01011010
Sorafenib-induced Hand- Foot Skin Reaction Treatment Terminated Hand-foot Skin Reaction|Rash NCT00667589
Study of G-202 (Mipsagargin) as Second-Line Therapy Following Sorafenib in Hepatocellular Carcinoma Completed Advanced Adult Hepatocellular Carcinoma NCT01777594
A Phase II Study of Weekly Genexol-PM in Patients With Hepatocelluar Carcinoma After Failure of Sorafenib Recruiting Carcinoma, Hepatocellular NCT03008512
Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Active, not recruiting Acute Myeloid Leukemia|Leukemia Cutis|Myeloid Neoplasm|Myeloid Sarcoma NCT01371981
Cardiac Biomarkers in Early Detection of Cardiotoxicity in Patients Receiving Sunitinib or Sorafenib Chemotherapy Terminated Malignant Neoplasm NCT00532064
BAY-43-9006 in Advanced, Metastatic Soft Tissue Sarcomas Completed Sarcoma, Soft Tissue NCT00406601
Palliative Treatment of Hepatocellular Carcinoma in Patient With CHILD B Cirrhosis Completed Hepatocellular Carcinoma|CHILD B NCT01357486
Sorafenib to Treat Children and Young Adults With Neurofibromatosis Type 1 and Inoperable Plexiform Neurofibromas Completed Neurofibromatosis Type I|Plexiform Neurofibroma NCT00727233
Palbociclib and Sorafenib, Decitabine, or Dexamethasone in Treating Patients With Recurrent or Refractory Leukemia Recruiting Recurrent Acute Lymphoblastic Leukemia|Recurrent Acute Myeloid Leukemia|Refractory Acute Lymphoblastic Leukemia|Refractory Acute Myeloid Leukemia NCT03132454
Sorafenib and Temozolomide in Treating Patients With Stage III or Stage IV Melanoma Unknown status Melanoma (Skin) NCT00811759
Sorafenib and Erlotinib in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer That Has Not Responded to Chemotherapy Unknown status Lung Cancer NCT00801385
A Research Study to Treat Patients With Advanced Hepatocellular Carcinoma Completed Carcinoma, Hepatocellular NCT00108953
A Study of Ramucirumab (IMC-1121B) Drug Product (DP) and Best Supportive Care (BSC) Versus Placebo and BSC as 2nd-Line Treatment in Participants With Hepatocellular Carcinoma After 1st-Line Therapy With Sorafenib Completed Hepatocellular Carcinoma NCT01140347
Phase II Study of Avelumab in Patients With Advanced Hepatocellular Carcinoma After Prior Sorafenib Treatment Active, not recruiting Carcinoma, Hepatocellular NCT03389126
Statin Combination Therapy in Patients Receiving Sorafenib for Advanced Hepatocellular Carcinoma Recruiting Overall Survival|Tumor Responses NCT03275376
Study of Cabozantinib (XL184) vs Placebo in Subjects With Hepatocellular Carcinoma Who Have Received Prior Sorafenib Active, not recruiting Hepatocellular Carcinoma NCT01908426
Efficacy, Safety, and Pharmacokinetic of MSC2156119J in Asian Participants With Hepatocellular Carcinoma Active, not recruiting Carcinoma, Hepatocellular NCT01988493
A Phase II Study of ABC294640 as Monotherapy in Patients With Advanced Hepatocellular Carcinoma Withdrawn Carcinoma, Hepatocellular NCT02939807
GIDEON Non-Nexavar Arm - HCC Patients Who Are Treated With Any Therapy Other Than Nexavar at Individual Study Start Withdrawn Carcinoma, Hepatocellular NCT01191385
Study of Regorafenib After Sorafenib in Patients With Hepatocellular Carcinoma Completed Carcinoma, Hepatocellular NCT01774344
Pilot Trial of "Chemo-Switch" Regimen to Treat Advanced Melanoma Terminated Melanoma NCT00673361
Cisplatin, Gemcitabine Hydrochloride, and Sorafenib Tosylate in Treating Patients With Transitional Cell Cancer of the Bladder Unknown status Bladder Cancer NCT01222676
Study of TAC-101 as Second Line Treatment in Patients With Advanced Hepatocellular Carcinoma Who Received Sorafenib as First Line Therapy Terminated Hepatocellular Carcinoma NCT00687596
Transarterial Chemoembolization Using Doxorubicin Beads With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery Unknown status Liver Cancer NCT01324076
A Study of Nivolumab in Combination With Ipilimumab in Participants With Advanced Hepatocellular Carcinoma Recruiting Hepatocellular Carcinoma NCT04039607
A Phase 2a Study of Modified Vaccinia Virus to Treat Sorafenib-naĂŻve Advanced Liver Cancer Completed Hepatocellular Carinoma NCT01636284
Irradiation Stent Placement Plus TACE for HCC and PVTT Recruiting Hepatocellular Carcinoma|Portal Vein Tumor Thrombosis NCT03730675
A Study of LY2157299 in Participants With Advanced Hepatocellular Carcinoma Active, not recruiting Hepatocellular Carcinoma NCT02178358
Sorafenib In Relapse of FMS-like Tyrosine Kinase 3 (FLT3)-Internal Tandem Duplication (ITD) AML Trial Completed Acute Myeloid Leukemia NCT02867891
Phase I Study of Sorafinib With Folfox4 as First-line Treatment in Advanced/Metastatic Gastric Cancer Available Gastric Cancer. NCT02209441
TRC105 for Liver Cancer That Has Not Responded to Sorafenib Completed Hepatocellular Carcinoma|Hepatocellular Cancer|Carcinoma, Hepatocellular NCT01375569
Combined Immunotherapy and Targeted Therapy for Advanced Liver Cancer Recruiting Advanced Liver Cancer NCT04163237
MEDI-573 in Combination With SOC in Unresectable or Metastatic HCC. Completed Unresectable or Metastatic Hepatocellular Carcinoma (HCC) NCT01498952
Incidence, Prevalence, and Symptom Burden Associated With Advanced Renal Cell Carcinoma in Commercially Insured Population (Pharmetrics) Completed Carcinoma, Renal Cell NCT01381601
QUILT-2.016: Study of AMG 479 With Biologics or Chemotherapy for Subjects With Advanced Solid Tumors Completed Advanced Malignancy|Advanced Solid Tumors|Cancer|Solid Tumors|Tumors NCT00974896
Efficacy and Safety of 'Immuncell-LC Group' and 'Non-treatment Group' in Nexavar Treated Patients for Advanced HCC Completed Advanced Hepatocellular Carcinoma NCT01897610
Exploratory Study of Radium-223 and VEGF-Targeted Therapy in Patients With Metastatic Renal Cell Carcinoma and Bone Mets Completed Metastatic Renal Cell Carcinoma NCT02406521
A Study to Evaluate SHR-1210 in Combination With FOLFOX4 Regimen as First-Line Therapy in Subjects With Advanced HCC Recruiting Advanced Hepatocellular Carcinoma NCT03605706
Combined Immunotherapy and Targeted Therapy for Hepatocellular Carcinoma Recruiting HepatoCellular Carcinoma NCT04152356
The Efficacy and Safety of Retreatment With TAI for Patients Who Showed TACE-resistant: a Randomized Controlled Trial Terminated Hepatocellular Carcinoma NCT02220088
Efficacy and Activity of BAY 43-9006 in Patients With Recurrent and/or Metastatic Head and Neck Cancer Completed Head and Neck Neoplasms NCT00199160
Axitinib (AG 013736) As Second Line Therapy For Metastatic Renal Cell Cancer Completed Kidney Neoplasms NCT00678392
18F-FLT-PET Imaging of the Brain in Patients With Metastatic Breast Cancer to the Brain Treated With Whole Brain Radiation Therapy With or Without Sorafenib: Comparison With MR Imaging of the Brain Active, not recruiting Metastatic Breast Cancer to the Brain NCT01621906
A Phase I / II Trial of Nintedanib in Asian Hepatocellular Carcinoma Patients Completed Carcinoma, Hepatocellular NCT00987935
Study of the Immunoresponse in Patients Treated With a Tyrosine Kinase Inhibitor Completed Renal Cell Carcinoma|GIST NCT00979381
Bevacizumab in Multiple Phase I Combinations Active, not recruiting Advanced Cancer NCT00543504
An Immuno-therapy Study to Evaluate the Effectiveness, Safety and Tolerability of Nivolumab or Nivolumab in Combination With Other Agents in Patients With Advanced Liver Cancer Active, not recruiting Hepatocellular Carcinoma NCT01658878
Incidence, Prevalence, and Symptom Burden Associated With Advanced Renal Cell Carcinoma in Commercially Insured Population (IHCIS) Completed Carcinoma, Renal Cell NCT01381614
DKN-01 Inhibition in Advanced Liver Cancer Recruiting Hepatocellular Carcinoma NCT03645980
SGI-110 in the Treatment of Advanced Hepatocellular Carcinoma (HCC) Completed Hepatocellular Carcinoma NCT01752933
TACE vs TACE+SBRT for Unresectable Hepatocellular Cancer Recruiting Carcinoma, Hepatocellular NCT02794337
c-Met Second-Line Hepatocellular Carcinoma Completed Carcinoma, Hepatocellular NCT02115373
Axitinib (AG-013736) For the Treatment of Metastatic Renal Cell Cancer Active, not recruiting Kidney Neoplasms NCT00920816
Efficacy and Safety Doxorubicin Transdrug Study in Patients Suffering From Advanced Hepatocellular Carcinoma Completed Carcinoma, Hepatocellular NCT01655693
Developing and Treating a Mouse Model of Acute Myeloid Leukemia Using Tissue Samples From Younger Patients With Acute Myeloid Leukemia Completed Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies NCT01576185
An Observational Study in Differentiated Thyroid Cancer Which is Radioactive Iodine (RAI) Refractory to Assess the Use of Multikinase Inhibitors Active, not recruiting Thyroid Neoplasms NCT02303444
Hepatic Impairment Study Completed Liver Disease NCT00829231
Research Study for Patients With Metastatic Renal Cell Carcinoma Terminated Carcinoma, Renal Cell NCT00110344
Adaptive Tyrosine Kinase Inhibitor (TKI) Therapy In Patients With Thyroid Cancer Active, not recruiting Thyroid Cancer|Thyroid Cancer, Medullary|Differentiated Thyroid Cancer|Papillary Thyroid Cancer|Follicular Thyroid Cancer|Poorly Differentiated Thyroid Gland Carcinoma NCT03630120
Dose Finding Study of AVE1642 in Patients With Advanced or Metastatic Liver Carcinoma Terminated Liver Carcinoma NCT00791544
Fingerprint Characterization of Advanced HCC Completed Carcinoma, Hepatocellular NCT02372162
Circulating Tumor Cells and Tumor DNA in HCC and NET Recruiting Carcinoma, Hepatocellular|Neuroendocrine Tumors NCT02973204
A Study of LY2157299 in Participants With Hepatocellular Carcinoma Active, not recruiting Carcinoma, Hepatocellular NCT01246986
Selecting Patient-Specific Biologically Targeted Therapy for Pediatric Patients With Refractory Or Recurrent Brain Tumors Unknown status Recurrent Childhood Brain Tumor NCT02015728
DNA Analysis of Blood and/or Tissue Samples From Patients With Primary Kidney Cancer Receiving Sorafenib on Clinical Trial MRC-RE05-SORCE Completed Kidney Cancer NCT00900536
Regorafenib Followed by Nivolumab in Patients With Hepatocellular Carcinoma (GOING) Recruiting Hepatocellular Carcinoma NCT04170556
Advanced Renal Cell Carcinoma, With Failure or Unsuitable on Prior Interferon-alpha or Interleukin-2 Based Therapy Terminated Carcinoma, Renal Cell NCT01195649
Biomarkers in Predicting Response to Chemotherapy in Patients With Advanced or Metastatic Melanoma Previously Treated With Carboplatin and Paclitaxel With or Without Sorafenib Tosylate Completed Melanoma (Skin) NCT01209299
Cabozantinib in Patients With Hepatocellular Carcinoma (ACTION) Not yet recruiting Hepatocellular Carcinoma NCT04316182
Pembrolizumab in Advanced Hepatocellular Carcinoma as Second-line Treatment After Failure of Sorafenib Recruiting Hepatocellular Carcinoma NCT03163992
Hormone Receptor Positive Disease Across Solid Tumor Types: A Phase I Study of Single-Agent Hormone Blockade and Combination Approaches With Targeted Agents to Provide Synergy and Overcome Resistance Active, not recruiting Solid Tumors|Advanced Cancer NCT01197170
The Efficacy of 5-fluorouracil/Mitomycin for the Patients With Pulmonary Metastasis of Hepatocellular Carcinoma Withdrawn Hepatocellular Carcinoma|Lung Metastasis NCT01953406
A Randomized Double-blind, Placebo-controlled Japanese Phase III Trial of ARQ 197 in Hepatocellular Carcinoma (HCC) Completed Liver Cancer NCT02029157
Hepatic Monitoring for Pazopanib Completed Carcinoma, Renal Cell NCT01449825
Efficacy Study of Pegylated Recombinant Human Arginase 1 as a Second-line Therapy in Patients With Advanced Liver Cancer Terminated Hepatocellular Carcinoma NCT02089763
QUILT-3.072: NANT Hepatocellular Carcinoma (HCC) Vaccine Withdrawn Hepatocellular Carcinoma Non-resectable|Hepatocellular Carcinoma Recurrent NCT03563170
Panobinostat and Everolimus in Treating Patients With Metastatic or Unresectable Renal Cell Cancer That Does Not Respond to Treatment With Sunitinib Malate or Sorafenib Tosylate Terminated Clear Cell Renal Cell Carcinoma|Recurrent Renal Cell Cancer|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer NCT01582009
Global Study Looking at the Combination of RAD001 Plus Best Supportive Care (BSC) and Placebo Plus BSC to Treat Patients With Advanced Hepatocellular Carcinoma. Completed Carcinoma NCT01035229
Targeted Therapy Selection Based on Tumor Tissue Kinase Activity Profiles for Patients With Advanced Solid Malignancies, an Exploratory Study Unknown status Advanced Solid Tumors|Inoperable|Metastasis NCT01190241
Phase 1b of ASLAN001 (Varlitinib) in Patients With Advanced/ Metastatic Hepatocellular Carcinoma (HCC) Recruiting Advanced/ Metastatic Hepatocellular Carcinoma NCT03499626
Study of Efficacy and Safety INC280 in Patients With Advanced Hepatocellular Carcinoma Withdrawn Advanced Hepatocellular Carcinoma NCT01964235
Study Of The Impact Of Inlyta In 2nd Line On The Treatment Outcomes Of mRCC Patients Treated With Sutent In 1st Line In The Real Life Setting Recruiting Metastatic Renal Cell Carcinoma (mRCC) NCT02184416
BATTLE-2 Program: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer Active, not recruiting Lung Cancer NCT01248247
Combination of BTK Inhibitor Overcomes Drug-resistance in Refractory/Relapsed FLT3 Mutant AML Enrolling by invitation FLT3-ITD Mutation|Acute Myeloid Leukemia|Brutons Tyrosine Kinase NCT03642236
Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma Active, not recruiting Hepatocellular Carcinoma NCT03298451
Pediatric Precision Laboratory Advanced Neuroblastoma Therapy Recruiting Neuroblastoma NCT02559778
Sequential Therapy in Metastatic Renal Cell Carinoma Completed Metastatic Renal Cell Carcinoma NCT01731158
Targeted Therapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia Recruiting Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndrome|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Refractory Adult Acute Lymphoblastic Leukemia NCT01620216
Efficacy Evaluation of TheraSphere in Patients With Inoperable Liver Cancer Active, not recruiting Unresectable Hepatocellular Carcinoma NCT01556490
Valproic Acid-Based 2-Agent Oral Regimens for Patients With Advanced Solid Tumor Completed Solid Tumors NCT00495872
A Study Of Crizotinib Plus VEGF Inhibitor Combinations In Patients With Advanced Solid Tumors. Withdrawn Carcinoma, Renal Cell|Glioblastoma|Carcinoma, Hepatocellular NCT01441388
Immune Checkpoint Therapy vs Target Therapy in Reducing Serum HBsAg Levels in Patients With HBsAg+ Advanced Stage HCC Recruiting Hepatocellular Carcinoma NCT03899428
RAD001 Plus Best Supportive Care (BSC) Versus BSC Plus Placebo in Patients With Metastatic Carcinoma of the Kidney Which Has Progressed After Treatment With Sorafenib and/or Sunitinib Completed Metastatic Renal Cell Carcinoma NCT00410124
Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery Recruiting Childhood Hepatocellular Carcinoma|Childhood Malignant Liver Neoplasm|Fibrolamellar Carcinoma|Hepatoblastoma|Hepatocellular Malignant Neoplasm, Not Otherwise Specified NCT03533582
A Pilot Study of Genomic Sequencing Guided Individualized Therapy in Gastrointestinal Cancers, GITIC Study Unknown status Gastrointestinal Cancers NCT02013089
ABT-888 and Temozolomide for Liver Cancer Terminated Hepatocellular Carcinoma NCT01205828
Erlotinib Plus Bevacizumab in Hepatocellular Carcinoma (HCC) as Second-line Therapy Active, not recruiting Liver Cancer NCT01180959
A Study of Ramucirumab (LY3009806) Versus Placebo in Participants With Hepatocellular Carcinoma and Elevated Baseline Alpha-Fetoprotein Recruiting Hepatocellular Carcinoma NCT02435433
A Randomized, Placebo-controlled, Double-blind Phase 2 Study With OSI-906 in Patients With Advanced HCC Terminated Advanced Hepatocellular Carcinoma (HCC) NCT01101906
A Phase 2 Study of Brivanib in Chinese Patients With Previously Treated Advanced HCC Completed Hepatocellular Carcinoma (HCC) NCT03516071
Viral Therapy in Treating Patient With Refractory Liver Cancer or Advanced Solid Tumors Active, not recruiting Advanced Malignant Solid Neoplasm|Hepatocellular Carcinoma NCT01628640
Study of Pembrolizumab and Radiotherapy in Liver Cancer Recruiting Hepatocellular Carcinoma NCT03316872
Personalized Targeted Inhibitors Treatment in Renal Cell Cancer Terminated Carcinoma, Renal Cell NCT02560012
Cardiovascular and Torsades de Pointes Monitoring for Pazopanib Completed Carcinoma, Renal Cell NCT01446224
A Food Effect and QTc Study of Perifosine in Patients With Advanced Malignancies Completed Cancer NCT01224730
A Study To Evaluate The Efficacy And Safety of The Investigational Drug PF-03446962 (A Monoclonal Antibody With Antiangiogenic Features) In Combination With Best Supportive Care Versus Placebo Plus Best Supportive Care In Patients Affected By Recurrent Liver Cancer Terminated Carcinoma, Hepatocellular NCT01911273
Epigenetic Reprogramming in Relapse AML Terminated Leukemia, Acute Myeloid NCT02412475
CRLX101(NLG207) in Combination With Bevacizumab for Metastatic Renal Cell Carcinoma (mRCC) Versus Standard of Care (SOC) Completed Metastatic Renal Cell Carcinoma NCT02187302
A Personalized Medicine Study for Patients With Advanced Cancer of the Breast, Prostate, Pancreas or Those With Refractory Acute Myelogenous Leukemia Recruiting Breast Cancer|Prostate Cancer|Pancreatic Cancer|Acute Myelogenous Leukemia NCT03878524
A Study of Dexanabinol in Combination With Chemotherapy in Patients With Advanced Tumours Unknown status Hepatocellular Carcinoma|Pancreatic Cancer NCT02423239
Personalized Kinase Inhibitor Therapy Combined With Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia Recruiting Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia NCT02779283
Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors Active, not recruiting Desmoplastic Small Round Cell Tumor|Ewing Sarcoma of Bone or Soft Tissue|Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor NCT01946529
Prediction of Response to Kinase Inhibitors Based on Protein Phosphorylation Profiles in Tumor Tissue From Advanced Renal Cell Cancer Patients Terminated Renal Cell Cancer NCT02071719
Genomics-Based Target Therapy for Children With Relapsed or Refractory Malignancy Recruiting Relapsed Pediatric Solid Tumor|Refractory Pediatric Solid Tumor|Relapsed Pediatric AML|Refractory Pediatric AML NCT02638428
Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: My Own Specific Treatment Recruiting Malignant Solid Neoplasms NCT02029001
Impact of BRAFV600E Intratumor Heterogeneity in Thyroid Cancer Treated With Tyrosine Kinase Inhibitors Unknown status Differentiated Thyroid Cancer NCT01700699
Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy Recruiting Rhabdomyosarcoma NCT01871766
Combination of Sintilimab and Stereotactic Body Radiotherapy in Hepatocellular Carcinoma (ISBRT01) Recruiting Hepatocellular Carcinoma NCT04167293
Cabozantinib toLERANCE Study in HepatoCellular Carcinoma (CLERANCE) Recruiting Hepatocellular Carcinoma NCT03963206
NEXT: Subsequent Exposure to Tyrosine Kinase Inhibition at Recurrence After Adjuvant Therapy in Renal Cell Carcinoma Terminated Renal Cell Carcinoma NCT01649180
Natural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1 Completed Neurofibromas|Neurofibromatosis Type 1 NCT00314119
Neoadjuvant Treatment With Regorafenib and Capecitabine Combined With Radiotherapy in Locally Advanced Rectal Cancer Recruiting Rectal Cancer NCT02910843
Lenalidomide for Advanced Hepatocellular Cancer:A Phase II Trial Completed Liver Cancer NCT00717756
Stereotactic Body Radiotherapy for Unresectable Hepatocellular Carcinoma Recruiting Localized Non-Resectable Adult Hepatocellular Carcinoma NCT01910909
Caphosol in Oral Mucositis Due to Targeted Therapy Completed Oral Complaints|Renal Cell Carcinoma|Hepatocellular Carcinoma|Gastrointestinal Stromal Tumors NCT01265810
A Phase II Trial of Perifosine Following Tyrosine Kinase Inhibitor (TKI) - Failure in Patients With Renal Cancer Completed Renal Cell Carcinoma NCT00448721
SARC024: A Blanket Protocol to Study Oral Regorafenib in Patients With Selected Sarcoma Subtypes Recruiting Liposarcoma|Osteogenic Sarcoma|Ewing/Ewing-like Sarcoma|Rhabdomyosarcoma NCT02048371
Outcome-related Factors in Patients With Metastatic Renal Cell Carcinoma Treated With Everolimus (ORCHIDEE) Terminated Renal Cell Carcinoma NCT02338570
Study Of AG-013736 In Patients With Refractory Metastatic Renal Cell Cancer Completed Kidney Neoplasms|Carcinoma, Renal Cell NCT00282048
Predicting Severe Toxicity of Targeted Therapies in Elderly Patients With Cancer Recruiting Cancer NCT02751827
Temsirolimus as Second-line Therapy in HCC Unknown status Unresectable or Metastatic Hepatocellular Carcinoma NCT01567930
Pazopanib in Combination With Capecitabine in Patients With Metastatic Breast Cancer Completed Metastatic Breast Cancer NCT01498458
Study On Fatigue- And Hand-Foot Syndrome-Related Quality Of Life In Patients With Metastatic Renal Cell Carcinoma Receiving A Tyrosine Kinase Inhibitor as First-Line Treatment Active, not recruiting Metastatic Renal Cell Carcinoma NCT02789137
Safety and Efficacy of Oncoxin Plus Surafineb in Hepatocellular Carcinoma Unknown status Quality of Life NCT01747642
[68Ga]DOTATATE-PET/MRI in Hepatocellular Carcinoma Recruiting Hepatocellular Carcinoma NCT03648073
Study to Determine the Efficacy of Regorafenib in Metastatic Colorectal Cancer Patients and to Discover Biomarkers Active, not recruiting Metastatic Colorectal Cancer NCT01949194
A Norwegian Observational Trial Evaluating the Treatment of Advanced Renal Cell Cancer Patients Under Treatment of Afinitor Completed Metastatic Renal Cell Carcinoma (mRCC) NCT01390519
Bevacizumab Plus Ixabepilone to Treat Patients With Advanced Kidney Cancer Completed Renal Cell Carcinoma NCT00923130
Lenalidomide as Second-line Treatment for Advanced Hepatocellular Carcinoma Completed Liver Cancer NCT01545804
Exploratory Clinical Study of Apatinib and SHR-1210 in Treating Advanced Hepatocellular Carcinoma or Gastric Cancer Unknown status Gastric Cancer|Hepatocellular Carcinoma NCT02942329
Safety and Efficacy of PD-1 Inhibitors in Patients With Liver Transplant Recruiting Hepatocellular Carcinoma|Liver Transplantation NCT03966209
Study of Pembrolizumab (MK-3475) as Monotherapy in Participants With Advanced Hepatocellular Carcinoma (MK-3475-224/KEYNOTE-224) Active, not recruiting Hepatocellular Carcinoma NCT02702414
Study of PolyIC and PD-1 mAb in Subjects With Unresectable Hepatocellular Carcinoma Recruiting Carcinoma, Hepatocellular NCT03732547
Trial of BIBF1120 (Nintedanib) in Patients With Recurrent or Metastatic Salivary Gland Cancer of the Head and Neck Unknown status Recurrent or Metastatic Salivary Gland Cancer of the Head and Neck NCT02558387
Ultrasound in Assessing Antiangiogenic Treatment in Patients With Advanced Kidney Cancer Unknown status Kidney Cancer|Metastatic Cancer NCT01105364
A Randomized Phase II Trial Comparing Therapy Based on Tumor Molecular Profiling Versus Conventional Therapy in Patients With Refractory Cancer Unknown status Reccurent/Metastatic Solid Tumor Disease NCT01771458
Apatinib for Metastatic Esophageal Cancer. Unknown status Esophageal Cancer|Metastatic Esophageal Cancer|Apatinib NCT02544737
A Phase II Study of Axitinib in Metastatic Non-clear Cell Renal Cell Carcinoma Patients Previously Treated With Temsirolimus Unknown status Renal Cell Carcinoma|Nonclear Cell|Temsirolimus Resistance NCT01798446
RAD001 for Patients With Radioiodine Refractory Thyroid Cancer Completed Thyroid Cancer NCT00936858
First-in-Human Safety and Tolerability Study of MTL-CEBPA in Patients With Advanced Liver Cancer Recruiting Hepatocellular Carcinoma|Liver Cancer NCT02716012
Study of the Combination of TACE With Apatinib in Patients With Hepatocellular Carcinoma Unknown status Hepatocellular Carcinoma NCT03066557
An Exploratory Correlative Study of Biomarkers in Patients With Metastatic Renal Cell Carcinoma Who Have Progressed After Sunitinib Therapy Withdrawn Carcinoma, Renal Cell NCT00538772
Efficacy of Apatinib in Radioactive Iodine-refractory Differentiated Thyroid Cancer Recruiting Differentiated Thyroid Cancer NCT03048877
Feasibility of High Dose PROton Therapy On Unresectable Primary Carcinoma Of Liver: Prospective Phase II Trial Recruiting Liver Neoplasm|Proton Therapy NCT02632864
Proton Beam Therapy in Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis Recruiting Liver Neoplasm|Portal Vein Tumor Thrombosis|Proton Therapy NCT02571946
Retrospective Analysis Of Progression Free Survival And Overall Survival In A National Cohort Of Patients With Metastatic Renal Cell Carcinoma Treated In Denmark From 2006-2010. DARENCA Study 2. Completed Renal Cell Carcinoma NCT01339962
A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia Recruiting Acute Myeloid Leukemia|Myelodysplastic Syndromes NCT03164057
Testing the Combination of Cabozantinib, Nivolumab, and Ipilimumab (CaboNivoIpi) for Advanced Differentiated Thyroid Cancer Recruiting Differentiated Thyroid Gland Carcinoma|Follicular Variant Thyroid Gland Papillary Carcinoma|Poorly Differentiated Thyroid Gland Carcinoma|Refractory Differentiated Thyroid Gland Carcinoma|Refractory Thyroid Gland Carcinoma|Tall Cell Variant Thyroid Gland Papillary Carcinoma|Thyroid Gland Follicular Carcinoma|Thyroid Gland Hurthle Cell Carcinoma|Thyroid Gland Papillary Carcinoma NCT03914300
A Phase I/II Study to Assess the Safety and Efficacy of TKI258 for the Treatment of Refractory Advanced/Metastatic Renal Cell Cancer Completed Advanced/ Metastatic Renal Cell Cancer NCT00715182
Avastin and Temsirolimus Following Tyrosine Kinase Inhibitor Failure in Patients With Advanced Renal Cell Carcinoma Completed Renal Cell Carcinoma|Kidney Cancer NCT00782275
Apatinib Plus Anti-PD1 Therapy for Advanced Osteosarcoma Completed Progression-free Survival|Overall Survival|Clinical Benefit Rate|Toxicity NCT03359018
Transarterial Chemoembolization (TACE) With Radiation Therapy (RT) in Advanced Hepatocellular Carcinoma (HCC) Unknown status Hepatocellular Carcinoma|Portal Vein Tumor Thrombosis NCT02290977
A Novel Immunotherapy PD-1 Antiboty to Suppress Recurrence of HCC Combined With PVTT After Hepatic Resection Recruiting Hepatocellular Carcinoma NCT03914352
Effectiveness and Safety of the Simultaneous Radiotherapy and Hyperthermia After Transarterial Chemoembolization in Hepatocellular Carcinoma Patients Combined With Portal Vein Tumor Thrombosis Completed Carcinoma. Hepatocellular NCT01911000
RT+ Anti-PD-1 for Patients With Advanced HCC (RT+PD-1-HCC) Not yet recruiting Hepatocellular Carcinoma NCT04193696
Topical Sildenafil as Pre-Treatment for Hand-Foot Skin Reaction Recruiting Hand Foot Skin Reaction NCT03229512
MiRNA as a Diagnostic and Prognostic Biomarker of Hepatocellular Carcinoma Not yet recruiting Carcinoma, Hepatocellular|Marker, Biological NCT02448056
Axitinib in R/M Salivary Gland Cancers of the Upper Aerodigestive Tract - SGC-AX14 Completed Salivary Gland Cancers NCT02857712
Sarcopenia in Patients With Gastrointestinal Stromal Tumours Completed Gastrointestinal Stromal Tumours NCT02877368
A Study of Apatinib for Advanced Hepatocellular Carcinoma Patients After First-line Treatment Failure Unknown status Hepatocellular Carcinoma NCT02772029
Everolimus in Patients With Metastatic Renal Cell Carcinoma Following Progression on Prior Bevacizumab Treatment Completed Metastatic Renal Cell Carcinoma NCT02056587
Safety and Efficacy of Allogeneic NK Cells Therapy in Patients With Advanced Hepatocellular Carcinoma Recruiting Hepatocellular Carcinoma NCT04162158
Carbon Ion Radiotherapy for Hepatocellular Carcinoma Recruiting Hepatocellular Carcinoma NCT01167374
pazopanib_NCRCC,Ph2 STUDY Completed Locally Advanced or Metastatic Non-clear Cell Type Renal Cell Carcinoma NCT01538238
Adjuvant Chemotherapy With FOLFOX in HCC Patients After Resection Recruiting Carcinoma, Hepatocellular NCT02738697
TACE Combined With Iodine-125 Seeds Implantation for HCC Enrolling by invitation Hepatocellular Carcinoma|Portal Vein Occlusion|Tumor Thrombus NCT03322280
Neoadjuvant and Adjuvant Nivolumab in HCC Patients Treated by Electroporation Recruiting Hepatocellular Carcinoma NCT03630640
Contribution of F-18 Fluoro-Deoxy-Glucose PET/CT (Positron Emission Tomography) to the Assessment of HCC (Hepato-cellular Carcinoma) Treatment Efficiency Unknown status Hepatocellular Carcinoma NCT01322477
A Positron Emission Tomography (PET) Imaging Agent [18F]-ODS2004436 as a Marker of EGFR Mutation in Subjects With NSCLC Completed Carcinoma, Non-Small-Cell Lung NCT02847377
Apatinib for Advanced Osteosarcoma After Failure of Standard Multimodal Therapy Completed Osteosarcoma|Metastasis NCT02711007
Validation of the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) Prognostic Classification for Targeted Therapies (TKI/mTOR Inhibitors) in Second Line After First Line Treatment With Pazopanib Completed Metastatic Renal Cell Carcinoma NCT03091465
Vandetanib to Treat Advanced Kidney Cancer Terminated Advanced Clear Cell Renal Carcinoma NCT01372813
ELR+CXCL Cytokines in Metastatic Kidney Cancers: Predictive Markers of Resistance to Sunitinib Active, not recruiting Metastatic Kidney Cancers NCT03097601
Transarterial RAdioembolization Versus ChemoEmbolization for the Treatment of Hepatocellular Carcinoma (HCC) Suspended Hepatocellular Carcinoma NCT01381211
RFA Combined With Oxaliplatin + 5-FluoroUracil/LeucoVorin (5-FU/LV) (FOLFOX4) for Recurrent HCC Unknown status Hepatocellular Carcinoma NCT02426450
Sunitinib or Cediranib for Alveolar Soft Part Sarcoma Recruiting Sarcoma, Alveolar Soft Part NCT01391962
A Dose Escalation Trial of Radiation Therapy (RT) for Hepatocellular Carcinoma (HCC) Unknown status Hepatocellular Carcinoma NCT00960167
HR Combined With FOLFOX4 for HCC With PVTT Unknown status Hepatocellular Carcinoma NCT02452853
Study of Microcirculatory Effects of Bevacizumab in Patients Treated for Metastatic Colon Cancer or Glioblastoma Completed Metastatic Colorectal Cancer|Glioblastoma|Bevacizumab|Capillaroscopy NCT01810744
Ponatinib for FLT3-ITD Acute Myelogenous Leukemia Recruiting Acute Myeloid Lukemia NCT02428543
Perfusion CT as a Predictor for Response to Antiangiogenic Therapy in Patients With Metastasized Renal Cell Carcinoma Completed Metastatic Renal Cancer NCT02086734
Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia Recruiting Acute Bilineal Leukemia|Acute Biphenotypic Leukemia|Acute Leukemia of Ambiguous Lineage|Acute Undifferentiated Leukemia|Mixed Phenotype Acute Leukemia|Mixed Phenotype Acute Leukemia, B/Myeloid, Not Otherwise Specified|Mixed Phenotype Acute Leukemia, T/Myeloid, Not Otherwise Specified|Recurrent Mixed Phenotype Acute Leukemia NCT02135874
Profile of Soluble and Cellular Biomarkers and of Functional Imaging During Antiangiogenic Therapies in Cancer Patients Terminated Hepatocellular Cancer|Non-small Cell Lung Cancer|Renal Cell Cancer|Colorectal Cancer NCT01507740
Tumor Kinase Inhibitor Concentrations Measured by PET Completed Disseminated Malignant Neoplasm NCT02111889
A Phase 2 Study of Cabozantinib in Japanese Patients With Advanced Hepatocellular Carcinoma Active, not recruiting Advanced Hepatocellular Carcinoma NCT03586973
Predictive Value of Drug Sensitivity Testing Tumorspheres From Patients With Metastatic Colorectal Cancer Recruiting Colorectal Cancer Metastatic NCT03251612
Real-world Study for Patients With Advanced Hepatobiliary Tumors Recruiting Objective Response Rate|Progression-free Survival|Overall Survival|Disease Control Rate|Duration of Response|Five-year Survival Rate|Quality of Life NCT03892577
Evaluation of Reporting of Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptor Inhibitors Associated Cardiovascular Adverse reactioN. Completed Cardiac Complication|Vascular Diseases NCT03413176
Ph II Study of Perifosine for Patients With Carcinoma of the Kidney Completed Kidney Cancer NCT00498966
Molecularly Target Therapy With FORFIRINOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma Recruiting Cholangiocarcinoma of the Extrahepatic Bile Duct|Gallbladder Cancer NCT03768375
Pharmacodynamic Effects of Anti-Vascular Endothelial Growth Factor Therapy in Patients With Advanced Malignancies Terminated Hypertension|Proteinuria NCT00698659
A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC Terminated Triple Negative Breast Cancer|Hepatocellular Carcinoma NCT03318562
Paediatric Hepatic International Tumour Trial Recruiting Hepatoblastoma|Carcinoma, Hepatocellular NCT03017326
Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma Completed Urothelial Carcinoma|Bladder Cancer|Urinary Bladder Neoplasms NCT02788201
Study of Iomab-B Prior to Hematopoietic Cell Transplant vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia Recruiting Acute Myeloid Leukemia|Leukemia, Acute Myeloid|Myeloid Leukemia, Acute|Leukemia, Myeloid, Acute|Acute Myelogenous Leukemia|Leukemia, Acute Myelogenous|Myelogenous Leukemia, Acute|AML|Bone Marrow Transplant NCT02665065
A Study to Investigate Nicotinic Acid on VEGFR Inhibitor-Associated Hand-Foot Skin Reactions Not yet recruiting Hand-Foot Skin Reaction (HFSR) NCT04242927
The Study of The Treatment of Postoperative Adjuvant Apatinib vs. TACE in Hepatocellular Carcinoma Patients Not yet recruiting Hepatocellular Carcinoma NCT03511703
The Study of Apatinib Plus Radiotherapy vs. Apatinib in the Treatment of Hepatocellular Carcinoma With BCLC-C Stage I and Stage II Portal Vein Tumor Thrombus Not yet recruiting Hepatocellular Carcinoma NCT03520257
Determination of Intratumoral Concentrations of Kinase Inhibitors in Patients With Advanced Solid Malignancies. Active, not recruiting Cancer|Advanced Solid Tumors NCT01636908
Frailty Phenotype Assessments to Optimize Treatment Strategies for Older Patients With Hematologic Malignancies Recruiting Leukemia, Acute|MDS NCT03680677
Molecularly Target Therapy With GEMOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma Recruiting Cholangiocarcinoma of the Extrahepatic Bile Duct|Gallbladder Cancer NCT02836847
Study of Individualized Therapies Selection for Patients With Metastatic Colorectal Carcinoma According to the Therapeutic Completed Adenocarcinoma of Colon|Adenocarcinoma of Rectum|Metastatic Disease NCT01703910
A Study of R1507 in Combination With Multiple Standard Chemotherapy Treatments in Patients With Advanced Solid Tumors Terminated Neoplasms NCT00811993
Sutent Rechallenge In mRCC Patients Completed Metastatic Renal Cell Carcinoma NCT01827254
Dose-Escalation Study of Ponatinib, a FLT3 Inhibitor, With and Without Combination of 5-Azacytidine, in Patients With FLT3-Mutated Acute Myeloid Leukemia (AML) Withdrawn Leukemia|FLT3-Mutated Acute Myeloid Leukemia|FLT3-Mutated High-Risk Myelodysplastic Syndrome NCT02829840
RF Ablation of Treatment of Metastatic Lesions in Patients Undergoing Antiangiogenic Therapy for Stage IV Renal Cell Carcinoma Withdrawn Renal Cell Carcinoma NCT00601120
Molecular Profiling and Matched Targeted Therapy for Patients With Metastatic Melanoma Not yet recruiting Melanoma NCT02645149
Transarterial Chemoembolization With Doxorubicin With or Without Everolimus in Treating Patients With Liver Cancer Terminated Liver Cancer NCT01009801
Role of LDH as a Predictor of Treatment Outcomes in Hepatocellular Carcinoma Unknown status Hepatocellular Carcinoma NCT03338166
Non-interventional Study of Cabozantinib in Adults With Advanced Renal Cell Carcinoma Recruiting Renal Cell Carcinoma NCT03419572
"Cocktail" Therapy for Hepatitis B Related Hepatocellular Carcinoma Not yet recruiting Hepatocellular Carcinoma NCT04317248
Clinical Outcome Of Advanced Renal Cell Carcinoma In Taiwan Completed Renal Cell Carcinoma NCT02776644
Expansion of Conventional Criteria for Liver Transplantation in Hepatocellular Carcinoma Through Downstaging Unknown status Carcinoma, Hepatocellular|Cirrhosis NCT01387503
Tumor Registry of Advanced Renal Cell Carcinoma Active, not recruiting Renal Cell Carcinoma NCT00610012
Clinical Evaluation of the Underlying Mechanisms of Targeted Therapy Related Toxicities Terminated Advanced or Metastatic Solid Malignancy NCT01758575
High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia Recruiting Acute Leukemia of Ambiguous Lineage|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia|Refractory Adult Acute Lymphoblastic Leukemia|Refractory Childhood Acute Lymphoblastic Leukemia NCT02551718
Temsirolimus-RCC-imaging Unknown status Renal Cell Cancer NCT01246817

References

Publication DOI Pubmed PMCID
Periodontal disease in adolescents: some clinical and microbiologic correlates of attachment loss. Journal of dental research J P Carlos, M D Wolfe, J J Zambon, A Kingman, 67, 12, None, None, 10.1016/j.neulet.2010.05.009 10.1016/j.neulet.2010.05.009 3198851 PMC3198851

Experiments

Compound Experiment type Investigated event Concentration Cell line Organism Animal model Stat protein Details
Sorafenib MTT Influence on cell viability N/A µM U87 Homo sapiens
Sorafenib MTT Influence on cell viability N/A µM LN229 Homo sapiens
Sorafenib MTT Influence on cell viability N/A µM AS515 Homo sapiens
Sorafenib MTT Influence on cell viability N/A µM U251 Homo sapiens
Sorafenib MTT Influence on cell viability N/A µM GS620 Homo sapiens
Sorafenib MTT Influence on cell viability N/A µM GS48 Homo sapiens
Sorafenib Flow cytometry Influence on cell cycle 3.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on cell cycle 3.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on cell cycle 3.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on cell cycle 3.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on cell cycle 3.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 3.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 7.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 15.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 3.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 7.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 15.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 3.00 µM U87 Homo sapiens p-STAT3(Y705)
Sorafenib Western Blot Influence on protein activity 7.00 µM U87 Homo sapiens p-STAT3(Y705)
Sorafenib Western Blot Influence on protein activity 15.00 µM U87 Homo sapiens p-STAT3(Y705)
Sorafenib Western Blot Influence on protein activity 3.00 µM U87 Homo sapiens STAT3
Sorafenib Western Blot Influence on protein activity 7.00 µM U87 Homo sapiens STAT3
Sorafenib Western Blot Influence on protein activity 15.00 µM U87 Homo sapiens STAT3
Sorafenib Western Blot Influence on protein activity 3.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 7.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 15.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 3.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 7.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 15.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 3.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 7.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 15.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 3.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 7.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 15.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 3.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 7.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 15.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 3.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 7.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on protein activity 15.00 µM U87 Homo sapiens
Sorafenib Trypan Blue staining Influence on cell viability N/A µM U87 Homo sapiens
Sorafenib Trypan Blue staining Influence on cell viability N/A µM LN229 Homo sapiens
Sorafenib Western Blot Influence on cell viability in transfected cells 3.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on cell viability in transfected cells 7.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on cell viability in transfected cells 15.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on cell viability in transfected cells 3.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on cell viability in transfected cells 7.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on cell viability in transfected cells 15.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on cell viability in transfected cells 3.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on cell viability in transfected cells 7.00 µM U87 Homo sapiens
Sorafenib Western Blot Influence on cell viability in transfected cells 15.00 µM U87 Homo sapiens
Sorafenib Bioluminescence Influence on tumor growth 100.00 mg/kg U87-Luc Mus musculus NIH Nu/Nu
Sorafenib Percent survival Influence on tumor growth 100.00 mg/kg U87-Luc Mus musculus NIH Nu/Nu
Sorafenib Immunohistochemistry Influence on tumor growth 100.00 mg/kg U87-Luc Mus musculus NIH Nu/Nu
Sorafenib Immunohistochemistry Influence on tumor growth 100.00 mg/kg U87-Luc Mus musculus NIH Nu/Nu
Sorafenib Immunohistochemistry Influence on tumor growth 100.00 mg/kg U87-Luc Mus musculus NIH Nu/Nu