S3I-V3-31

Name Value
Weight 0.000 N/A
Zinc ID N/A
Smiles N/A
Molecular formula N/A
Mode of inhibition Direct STAT; purine scaffold
CAS N/A

Clinical Trials

Study title Status Conditions Link

References

Publication DOI Pubmed PMCID
Hyperplastic and neoplastic endocrine cells of the pancreas in aspiration biopsy. Diagnostic cytopathology G K Nguyen, N A Rayani, 2, 3, None, None, 10.1021/ml100224d 10.1021/ml100224d 3021410 PMC3021410

Filter data

Compound S3I-V3-31
Experiment types CyQUANT, Western Blot
Concentrations 100.00, 200.00, 300.00, 40.00, 400.00, 500.00
Cell lines DU145, MDA-MB-231, NIH3T3, NIH3T3/v-Src, Panc-1, TE-71
Organisms Homo sapiens, Mus musculus
Animal models
STAT proteins STAT3, p-STAT3 (Y705)
Other ERK1/2, p-ERK1/2, p-SRC, β-actin

Experiments

Compound Experiment type Investigated event Concentration Cell line Organism Animal model Stat protein Details
S3I-V3-31 Western Blot Influence on protein activity 40.00 µM MDA-MB-231 Homo sapiens p-STAT3 (Y705)
S3I-V3-31 Western Blot Influence on protein activity 40.00 µM MDA-MB-231 Homo sapiens STAT3
S3I-V3-31 Western Blot Influence on protein activity 40.00 µM MDA-MB-231 Homo sapiens
S3I-V3-31 Western Blot Influence on protein activity 40.00 µM MDA-MB-231 Homo sapiens
S3I-V3-31 Western Blot Influence on protein activity 40.00 µM MDA-MB-231 Homo sapiens
S3I-V3-31 Western Blot Influence on protein activity 40.00 µM MDA-MB-231 Homo sapiens
S3I-V3-31 Western Blot Influence on protein activity 40.00 µM NIH3T3/v-Src Mus musculus p-STAT3 (Y705)
S3I-V3-31 Western Blot Influence on protein activity 40.00 µM NIH3T3/v-Src Mus musculus STAT3
S3I-V3-31 Western Blot Influence on protein activity 40.00 µM NIH3T3/v-Src Mus musculus
S3I-V3-31 Western Blot Influence on protein activity 40.00 µM NIH3T3/v-Src Mus musculus
S3I-V3-31 Western Blot Influence on protein activity 40.00 µM NIH3T3/v-Src Mus musculus
S3I-V3-31 Western Blot Influence on protein activity 40.00 µM NIH3T3/v-Src Mus musculus
S3I-V3-31 CyQUANT Influence on cell viability 100.00 µM TE-71 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 200.00 µM TE-71 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 300.00 µM TE-71 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 400.00 µM TE-71 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 500.00 µM TE-71 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 100.00 µM NIH3T3 Mus musculus
S3I-V3-31 CyQUANT Influence on cell viability 200.00 µM NIH3T3 Mus musculus
S3I-V3-31 CyQUANT Influence on cell viability 300.00 µM NIH3T3 Mus musculus
S3I-V3-31 CyQUANT Influence on cell viability 400.00 µM NIH3T3 Mus musculus
S3I-V3-31 CyQUANT Influence on cell viability 500.00 µM NIH3T3 Mus musculus
S3I-V3-31 CyQUANT Influence on cell viability 100.00 µM MDA-MB-231 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 200.00 µM MDA-MB-231 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 300.00 µM MDA-MB-231 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 400.00 µM MDA-MB-231 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 500.00 µM MDA-MB-231 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 100.00 µM Panc-1 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 200.00 µM Panc-1 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 300.00 µM Panc-1 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 400.00 µM Panc-1 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 500.00 µM Panc-1 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 100.00 µM DU145 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 200.00 µM DU145 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 300.00 µM DU145 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 400.00 µM DU145 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 500.00 µM DU145 Homo sapiens
S3I-V3-31 CyQUANT Influence on cell viability 100.00 µM NIH3T3/v-Src Mus musculus
S3I-V3-31 CyQUANT Influence on cell viability 200.00 µM NIH3T3/v-Src Mus musculus
S3I-V3-31 CyQUANT Influence on cell viability 300.00 µM NIH3T3/v-Src Mus musculus
S3I-V3-31 CyQUANT Influence on cell viability 400.00 µM NIH3T3/v-Src Mus musculus
S3I-V3-31 CyQUANT Influence on cell viability 500.00 µM NIH3T3/v-Src Mus musculus