Resveratrol

Name Value
Weight 228.247 g/mol
Zinc ID ZINC6787
Smiles Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1
Molecular formula C14H12O3
Mode of inhibition JAK1, STAT; Natural product
CAS 501-36-0

Clinical Trials

Study title Status Conditions Link
Pilot Study to Evaluate the Plasma Profile of Revifast Completed Nutrient; Excess|Product Use Issue NCT04258306
Micronised Resveratrol as a Treatment for Friedreich Ataxia Recruiting Friedreich Ataxia NCT03933163
Evaluating the Clinical Efficacy of Resveratrol in Improving Metabolic and Skeletal Muscle Function in Patients With Heart Failure Recruiting Congestive Heart Failure Chronic NCT03525379
The Effects of Resveratrol Supplementation on Inflammation and Cognitive Performance in Healthy Adults Completed Cognitive Change|Mood|Systemic Inflammation NCT04314739
Short Interval Resveratrol Trial in Cardiovascular Surgery Recruiting Diabetes Mellitus, Type 2|Coronary Artery Disease NCT03762096
Long-term Resveratrol and Metabolism Completed Pre-diabetes NCT02565979
Multimodal Investigation of the Neuroprotective Effects of Resveratrol (MINER) Recruiting Gulf War Illness NCT03665740
Resveratrol In Chronic Obstructive Pulmonary Disease (COPD) Patients (CARMENS-trial) Completed Pulmonary Disease, Chronic Obstructive NCT02245932
The Effects of Resveratrol Supplementation on Cognition, Cerebral Blood Flow, Microbiota and Systemic Inflammation. Completed Cognitive Function and Mood|Cerebral Blood Flow|Systemic Inflammation|Gut Microbiota|Overweight and Obesity NCT03448094
Resveratrol and Sirolimus in Lymphangioleiomyomatosis Trial Recruiting Lymphangioleiomyomatosis NCT03253913
Resveratrol as a Preventive Treatment of OHSS Completed Infertility NCT03446625
Effects of Resveratrol in Patients With Type 2 Diabetes Completed Type 2 Diabetes NCT01677611
Pharmacokinetics of Trans-resveratrol Based Nutritional Supplement and Its Three Metabolites in Human Eyes and Blood Unknown status Eye Disease NCT02321176
Nicotinamide Riboside With and Without Resveratrol to Improve Functioning in Peripheral Artery Disease Recruiting Peripheral Artery Disease NCT03743636
Resveratrol for Pain Due to Endometriosis Completed Endometriosis NCT02475564
Effect of Resveratrol on Metabolic Parameters and Oocyte Quality in PCOS Patients Completed Androgen Profile|Inflammatory Markers|IVF Outcome NCT01782911
Impact of Resveratrol on Brain Function and Structure Completed Healthy NCT02621554
Regulation of Intestinal and Hepatic Lipoprotein Secretion by Resveratrol Completed Dyslipidaemia|Insulin Resistance NCT01451918
A Biological Study of Resveratrol's Effects on Notch-1 Signaling in Subjects With Low Grade Gastrointestinal Tumors Completed Neuroendocrine Tumor NCT01476592
Effects of Resveratrol on Inflammation in Type 2 Diabetic Patients Completed Type 2 Diabetes Mellitus|Inflammation|Insulin Resistance|Other Disorders of Bone Density and Structure NCT02244879
Effect of Administration of Resveratrol on Glycemic Variability in Individuals With Type 2 Diabetes Mellitus Terminated Type 2 Diabetes Mellitus NCT02549924
Resveratrol and First-degree Relatives of Type 2 Diabetic Patients Completed Pre-diabetes NCT02129595
Effects of High-Dose Resveratrol in Non-Diabetic Obese Males Completed Obesity|Diabetes NCT02247596
Resveratrol's Effects on Inflammation and Oxidative Stress in Chronic Kidney Disease Completed Chronic Renal Insufficiency NCT02433925
A Study of Resveratrol as Treatment for Friedreich Ataxia Completed Friedreich Ataxia NCT01339884
Resveratrol for Exudative Age-Related Macular Degeneration Unknown status AMD|Age-related Macular Degeneration|Choroidal Neovascularisation NCT02625376
Resveratrol and Type 2 Diabetes Unknown status Type 2 Diabetes NCT01638780
Resveratrol and Serum Apo A-I Completed Dyslipidemia NCT01364961
RESveratrol To Improve Outcomes in oldeR pEople With PAD (the RESTORE Trial) Completed Peripheral Arterial Disease NCT02246660
An Open Label Study Evaluating the Effectiveness of Omega Q Plus® Resveratrol at Increasing Blood Levels of CoQ10 Completed CoQ10 Blood Levels|CoQ10 Blood Levels With Statin Use NCT02415114
Effect of Resveratrol Administration on Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion Completed Metabolic Syndrome X NCT02114892
Can Resveratrol Improve Insulin Sensitivity and Preserve Beta Cell Function Following Gestational Diabetes? Unknown status Gestational Diabetes NCT01997762
Resveratrol: A Potential Anti- Remodeling Agent in Heart Failure, From Bench to Bedside Recruiting Dilated Cardiomyopathy NCT01914081
Anti-inflammatory and Antioxidant Effects of Resveratrol on Healthy Adults. Completed Chronic Subclinic Inflammation|Redox Status NCT01492114
Resveratrol and Midazolam Metabolism Completed Healthy NCT01173640
Resveratrol Trial for Relief of Pain in Pseudoachondroplasia Recruiting Pseudoachondroplasia NCT03866200
Pilot Study Of The Effects Of Resveratrol On Endothelial Function In Subjects With Type 2 Diabetes Mellitus Completed Type 2 Diabetes Mellitus NCT01038089
Resveratrol Supplementation in Patients With Mitochondrial Myopathies and Skeletal Muscle Fatty Acid Oxidation Disorders Completed Mitochondrial Myopathies|Fatty Acid Oxidation Defects NCT03728777
Resveratrol in Knee Osteoarthritis Recruiting Knee Osteoarthritis NCT02905799
The Effects of Resveratrol Supplement on Biochemical Factors and Hepatic Fibrosis in Patients With Nonalcoholic Steatohepatitis Completed Non Alcoholic Fatty Liver NCT02030977
Resveratrol in Patients With Non-alcoholic Fatty Liver Disease Completed Fatty Liver NCT01464801
Long-term Investigation of Resveratrol in Obesity Completed Obesity|Inflammation|Insulin Sensitivity|Osteoporosis NCT01412645
Pilot Study of Resveratrol in Older Adults With Impaired Glucose Tolerance Unknown status Impaired Glucose Tolerance NCT01375959
Resveratrol and Vascular Function in CKD Recruiting Chronic Kidney Diseases|Endothelial Dysfunction NCT03597568
Effects of Resveratrol Supplements on Vascular Health in Postmenopausal Women Completed Cardiovascular Disease NCT01564381
Resveratrol and Human Hepatocyte Function in Cancer Withdrawn Liver Cancer NCT02261844
Effects of Micronized Trans-resveratrol Treatment on Polycystic Ovary Syndrome (PCOS) Patients Unknown status Polycystic Ovary Syndrome (PCOS) NCT01720459
Pharmacokinetics of Resveratrol Comprising Products Completed Healthy NCT01747252
Effects of Trans-Resveratrol in Endothelial Function in Hypertensive Patients Completed Endothelial Dysfunction NCT02616822
Resveratrol in Type2 Diabetes and Obesity Unknown status Type 2 Diabetes|Obesity|Insulin Resistance NCT01158417
The Cognitive and Cerebral Blood Flow Effects of Resveratrol Completed Cognitive and Cerebral Blood Flow Effects of Resveratrol NCT01010009
Use of Resveratrol to Decrease Acute Secondary Brain Injury Following Sports-Related Concussions in Boxers Completed Sports Concussion NCT01321151
A Case Control Study of Resveratrol Effects in Coronary Artery Disease Patients With Metabolic Syndrome Completed Metabolic Syndrome|Coronary Artery Disease NCT02137421
The Effects of Resveratrol Supplementation on Measurements of Health and Human Performance Unknown status Inflammation NCT01244360
Short-term Investigation of Resveratrol on Fat Metabolism in Morbidly Obese Women Undergoing Gastric Bypass Surgery Unknown status Obesity NCT01826279
Resveratrol With or Without Piperine to Enhance Plasma Levels of Resveratrol Completed Focus of the Study: Normal Volunteers NCT01324089
Resveratrol and Cardiovascular Health in the Elderly Recruiting Vascular Resistance|Hypertension NCT01842399
Resveratrol's Effects in Diabetic Nephropathy Completed Diabetic Nephropathy NCT02704494
Resveratrol for Alzheimer's Disease Completed Alzheimer's Disease NCT01504854
Resveratrol and Huntington Disease Completed Huntington Disease NCT02336633
Resveratrol and the Metabolic Syndrome Completed Obesity|Insulin Resistance|Metabolic Syndrome NCT01714102
Resveratrol for Patients With Colon Cancer Completed Colon Cancer|Cancer NCT00256334
The Curative Effect and Security of Interferon Combined Resveratrol on HBeAg Positive Chronic Hepatitis B Patients Completed Hepatitis B NCT03546530
Efficacy and Safety of Resveratrol and Lipoic Acid Transdermal Patch for Lipolysis in Overweight Volunteers Completed Lipolysis NCT03062163
Supplementation of 500mg Trans-resveratrol Within Hypoxic and Normoxic Conditions, in Healthy Humans. Completed Hypoxia, Brain NCT03100019
Resveratrol Supplementation on Exercise in Healthy Sedentary Adults Completed Sedentary Lifestyle NCT01615445
Efficacy of Resveratrol in Depression Recruiting Depression NCT03384329
Cognitive Effects of 500mg Trans-resveratrol Completed Cognitive Performance|Mood NCT01794351
The Impact of Acute Trans-resveratrol Administration on Whole Body Metabolism During Cognitive Demand. Completed Cognitive Change NCT03546075
Effect of Resveratrol and Vitamin C on Insulin Resistance Among Postmenopausal Women Recruiting Postmenopausal|Insulin Resistance NCT03090997
The Effects of Resveratrol on the Complications of Patients With Hemodialysis Completed Chronic Kidney Disease NCT03352895
Resveratrol for the Treatment of Non Alcoholic Fatty Liver Disease and Insulin Resistance in Overweight Adolescents Completed NAFLD|TYPE 2 DIABETES|METABOLIC SYNDROME NCT02216552
The Cerebral Hemodynamic and Cognitive Effects of Acute Resveratrol Administration in Young, Healthy Adults at Stimulated Altitude. Completed Hypoxia, Altitude|Brain NCT03541993
Resveratrol, Cardiovascular Risk Markers And Cognitive Performance In Patients With Schizophrenia Completed Schizophrenia NCT02062190
The Curative Effect of Entecavir Combined Resveratrol on HBV patients-a Multi-center, Random, Open Clinical Trial Completed Hepatitis NCT03509688
Long-term Investigation of Resveratrol on Fat Metabolism in Obese Men With Nonalcoholic Fatty Liver Disease Completed Obesity|Nonalcoholic Fatty Liver Disease NCT01446276
Oral Resveratrol to Prevent Post-ERCP Pancreatitis Unknown status Pancreatitis, Acute|Gastrointestinal Disease NCT02947932
Resveratrol in Metabolic Syndrome: Effect on Platelet Hyper-reactivity and HDL Lipid Peroxidation Completed Metabolic Syndrome NCT02219906
Resveratrol in Postmenopausal Women With High Body Mass Index Completed Healthy, no Evidence of Disease NCT01370889
Resveratrol to Enhance Vitality and Vigor in Elders Completed Mitochondrial Function|Physical Function NCT02123121
Effects of Simvastatin and Micronized Trans-resveratrol Treatment on Polycystic Ovary Syndrome (PCOS) Patients Unknown status PCOS, Insulin Resistance NCT02766803
Nebulized Resveratrol Plus Carboxymethyl-β-Glucan for Reducing IL-5 in Children With Allergic Rhinitis Completed Allergic Rhinitis NCT03349619
Influence of Caloric Restriction and Resveratrol in the Sirtuin System in Women and Men Aged 55 to 65 Years Completed Vascular System Injuries|Lipid Metabolism Disorders|Endothelial Disfunction NCT01668836
Resveratrol for Improved Performance in the Elderly Completed Memory NCT01126229
Resveratrol-Leucine Metabolite Synergy in Pre-diabetes Completed Impaired Glucose Tolerance NCT01593605
Potential Beneficial Effects of Resveratrol Completed Metabolic Syndrome|Obesity NCT01150955
Effect of Resveratrol on Age-related Insulin Resistance and Inflammation in Humans Completed Type 2 Diabetes Mellitus|Insulin Resistance NCT01354977
Cerebral Blood Flow Effects of Resveratrol and Piperine in Humans Completed Healthy NCT01331382
Resveratrol in Treating Patients With Colorectal Cancer That Can Be Removed By Surgery Completed Adenocarcinoma of the Colon|Adenocarcinoma of the Rectum|Stage I Colon Cancer|Stage I Rectal Cancer|Stage II Colon Cancer|Stage II Rectal Cancer|Stage III Colon Cancer|Stage III Rectal Cancer NCT00433576
Efficacy and Safety of Resveratrol and Carbossimetyl Beta Glucan in Treatment of Upper Airways Disease in Infancy Completed Common Cold NCT03683108
Effects of Resveratrol on Endothelial Function in Type 2 Diabetes Mellitus Completed Diabetes Mellitus NCT01881347
Chronic Resveratrol Supplementation in Healthy Humans Completed Healthy NCT01640197
Resveratrol and Exercise to Treat Functional Limitations in Late Life Completed Aging NCT02523274
Evaluation of the Beneficial Effects of a Nasal Spray of Resveratrol in Children With Seasonal Allergic Rhinitis Completed Seasonal Allergic Rhinitis NCT02130440
Cerebrovascular and Cognitive Improvement by Resveratrol (resVida) and Fruitflow-II (CCIRF-II) Unknown status Memory Impairment NCT01766180
Effect of Antioxidant Intake on Cardiovascular Risk Completed Effect of Resveratrol and Curcumin on Inflammation NCT01964846
Pilot Study of the Effects of Resveratrol Supplement in Mild-to-moderate Alzheimer's Disease Withdrawn Alzheimer Disease NCT00743743
The Functional and Emotional Benefits of Replenix Power of Three With Resveratrol Recruiting Acne Vulgaris NCT03563365
Effect of Resveratrol on Serum IGF2 Among African American Women Active, not recruiting Chemoprevention NCT04266353
Resveratrol in Healthy Adult Participants Completed Healthy, no Evidence of Disease NCT00721877
A Clinical Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of SRT501 in Subjects With Colorectal Cancer and Hepatic Metastases Completed Neoplasms, Colorectal NCT00920803
The Effects of Resveratrol and Acute Exercise on Endothelial Function in Postmenopausal Women Completed Endothelial Dysfunction NCT02256540
Bioavailability of Resveratrol From Vineatrol30 Extract Incorporated Into Micelles Completed Safety After Oral Intake|Pharmacokinetics After Oral Intake NCT02944097
Mechanisms of Metabolic Regulation of Resveratrol on Humans With Metabolic Syndrome Withdrawn Insulin Resistance NCT00654667
Reresveratrol Administered to Healthy Male Subjects Completed Healthy Subjects|Heme Oxygenase NCT01768507
UMCC 2003-064 Resveratrol in Preventing Cancer in Healthy Participants Completed Unspecified Adult Solid Tumor, Protocol Specific NCT00098969
Resveratrol-enriched Grape Extract (Stilvid) in Primary and Secondary Prevention of Cardiovascular Disease Completed Cardiovascular Diseases NCT01449110
A Clinical Study to Assess the Safety and Activity of SRT501 Alone or in Combination With Bortezomib in Patients With Multiple Myeloma Terminated Multiple Myeloma NCT00920556
Cardiovascular Health of Older Adults and Resveratrol (CORE) Completed Aging NCT02909699
Phase I Biomarker Study of Dietary Grape-Derived Low Dose Resveratrol for Colon Cancer Prevention Unknown status Colon Cancer NCT00578396
Improving Cardiovascular Health in Patients With Chronic Obstructive Pulmonary Disease Active, not recruiting Chronic Obstructive Pulmonary Disease NCT03819517
Randomized Trial of a Nutritional Supplement in Alzheimer's Disease Completed Alzheimer's Disease NCT00678431
Effect of Food on BIA 6-512 (Trans-resveratrol) Completed Parkinson Disease NCT03095092
The Effect of Resveratrol Based Nutritional Supplement on Choroidal Thickness Unknown status Eye Disease NCT02321189
Effects of Dietary Antioxidants to Prevent Cardiovascular Disease Completed Hypercholesterolemia|Healthy NCT02409537
Tolerability and Steady-state Pharmacokinetics of BIA 6-512 Completed Parkinson Disease NCT03093389
Pharmacokinetic Profile of BIA 6-512 in Healthy Elderly Subjects Versus Healthy Young Subjects Completed Parkinson Disease NCT03095105
Effect of resVida on Liver Fat Content Completed Elevated Liver Fat Content and Insulin Resistance NCT01635114
Effect of Resvida, a Comparison With Calorie Restriction Regimen Completed Obesity|Metabolic Syndrome|Diabetes|Aging NCT00823381
resVida and Fat Oxidation Completed Obesity NCT00998504
BDPP Treatment for Mild Cognitive Impairment (MCI) and Prediabetes or Type 2 Diabetes Mellitus (T2DM) Recruiting Mild Cognitive Impairment|Alzheimer's Disease NCT02502253
Tolerability, Safety and Pharmacokinetics of Four Single-doses of BIA 6-512 (Trans-resveratrol) and Their Effect on the Levodopa Pharmacokinetics Completed Parkinson Disease NCT03091543
Therapeutic Metabolic Intervention in Patients With Spastic Paraplegia SPG5 Completed Spastic Paraplegia, Hereditary NCT02314208
Dietary Polyphenols and Insulin Sensitivity in Overweight and Obese Humans Completed Healthy NCT02381145
Non-pulmonary Contributors of Exercise Intolerance in Patients With Cystic Fibrosis Active, not recruiting Cystic Fibrosis NCT04166396
Obstructive Sleep Apnea-induced Changes in Adipose and Liver Tissue and Effects of Massive Weight Loss on Inflammation Completed Obesity|Obstructive Sleep Apnea NCT02419092
Multi-ingredient Nutrition Supplement in Older Adults Unknown status Physical Disability NCT02001831
Effect of Whole-grape Powder on Body Composition, Fat and Bone Serum Biomarkers in Postmenopausal Women Completed Obesity NCT01717820
Estrogen and Diabetes Recruiting Diabetes Mellitus, Type 1 NCT03436992
Healthy Aging Through Functional Food Completed Glucose Intolerance|Aortic Stiffness|Vasodilation NCT02095873
Dietary Polyphenols and Lipid Oxidation Completed Obesity, Insulin Sensitivity, Type 2 Diabetes Mellitus NCT01302639
Safety and Efficacy of a Dietary Supplement in Females With Cellulite Terminated Cellulite (Orange Peel Skin) NCT01321268
Effects of Dietary Interventions on the Aging Brain Unknown status Healthy NCT00996229
Effects of Short-term Curcumin and Multi-polyphenol Supplementation on the Anti-inflammatory Properties of HDL Unknown status Inflammation|Atherosclerosis|Cardiovascular Disease NCT02998918
Bioavailability Study of Different Dietary Antioxidants in Volunteers Completed Cardiovascular Disease NCT01199549
Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics Completed Parkinson Disease NCT03094156
Evaluation of Oral Lipid Ingestion in Relation to Ovarian Androgen Secretion in Polycystic Ovary Syndrome (PCOS) Terminated Polycystic Ovary Syndrome NCT01489319
To Evaluate the Effect of Reveratrol,Folic Acid, Vitamin D, Vitamin B12 and B6 in Male Infertility Recruiting Male Infertility NCT03864198
Grape Polyphenol Kinetics in Humans Completed Healthy Volunteers NCT01751750
Mechanisms for Vascular Dysfunction and Exercise Tolerance in CF Recruiting Cystic Fibrosis NCT02690064
Effects of Dietary Interventions on the Brain in Mild Cognitive Impairment (MCI) Completed Mild Cognitive Impairment NCT01219244
Development of a Marker of Adherence for Tracking Consumption of Nutrient Supplements Active, not recruiting Adherence, Treatment NCT04040543
Multi-ingredient Supplement for Strength and Power Completed Supplement NCT01971723
Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose of Levodopa/Benserazide 200/50 mg Plus a Single-dose of Nebicapone 150 mg Completed Parkinson Disease NCT03097211
NATURE 3.1_New Approach for the Reduction of REnal Uremic Toxins Completed Chronic Kidney Diseases|Healthy NCT03815786
Effect of Banaba (Lagerstroemia Speciosa) on Metabolic Syndrome, Insulin Secretion and Insulin Sensitivity Completed Metabolic Syndrome X NCT02767869
NATURE 3.2_New Approach for the Reduction of REnal Uremic Toxins Completed Hemodialysis NCT03946176
Effects of Peanut and Peanut Butter Consumption on Blood Lipids and Glycemic Control in Adults With Type 2 Diabetes Completed Type 2 Diabetes NCT00937222
Effects of Botanical Microglia Modulators in Gulf War Illness Active, not recruiting Gulf War Illness NCT02909686
Influence of Instaflex Advanced Supplement on Joint Function Completed Knee Discomfort NCT03041077
The Effects of Red Wine Polyphenols on Microvascular Dysfunction Completed Obesity NCT01518764
Effect of BGG on Glucose Metabolism and Other Markers of Metabolic Syndrome Completed Pre Diabetes NCT02834078
Assessing the Value of Red Grapes Polyphenol Supplementation on Metabolic Parameters in Obese Insulinoresistant Subjects Unknown status Obesity|Insulin Resistance|Menopause NCT02633150
Physiological Effects of Grape Seed Extract in Diastolic Heart Failure Completed Diastolic Heart Failure|Hypertensive Heart Disease|Heart Failure With Preserved Ejection Fraction|Hypertension|Oxidative Stress NCT01185067
Can Fish Oil and Phytochemical Supplements Mimic Anti-Aging Effects of Calorie Restriction? Completed Healthy Volunteers NCT01752868
Diabetic Retinopathy Functional Evaluation Study: Monitoring Carotenoid Vitamins Treatment Using ERG Recruiting Diabetes|Diabetic Retinopathy NCT04117022
Pilot Study of the Effect of Purple Rice on Glucose Tolerance, Serum Lipids and Inflammation Completed Type 2 Diabetic NCT01720511
Prospective Study of Adjunctive Carotenoids Plus Anti-oxidants in Anti-VEGF Treated Diabetic Macular Edema Not yet recruiting Center-involved Diabetic Macular Edema (CI-DME) NCT03866005
Disposition of Dietary Polyphenols and Methylxanthines in Mammary Tissues From Breast Cancer Patients Completed Breast Cancer NCT03482401
Dietary Intervention in Follicular Lymphoma Unknown status Follicular Lymphoma NCT00455416
Study of Supplement's Antioxidant Properties That Contains Natural Extracts Unknown status Healthy NCT02837107
Short Term Efficacy and Safety of Perispinal Administration of Etanercept in Mild to Moderate Alzheimer's Disease Completed Alzheimer's Disease NCT01716637
Effect of Red Grape Cells (RGC) Powder Consumption on Measures of Aerobic Fitness and Mood Completed Healthy NCT01832584
Pazopanib and Paclitaxel as First-Line Treatment for Subjects With Unresectable Stage III and Stage IV Melanoma Completed Stage III Melanoma|Stage IV Melanoma|Unresectable Melanoma NCT01107665
Oral Bioavailability and Bioactivity of Prenylflavonoids From Hops Completed Safety After Oral Intake|Pharmacokinetics After Oral Intake|Immune Cells Activity NCT03140397

References

Publication DOI Pubmed PMCID
Resveratrol eliminates cancer stem cells of osteosarcoma by STAT3 pathway inhibition. PloS one Lihua Peng, Dianming Jiang, 13, 10, None, 2018-10-24, 10.1371/journal.pone.0205918 10.1371/journal.pone.0205918 30356255 PMC6200233
Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells. Blood Anjana Bhardwaj, Gautam Sethi, Saroj Vadhan-Raj, Carlos Bueso-Ramos, Yasunari Takada, Upasna Gaur, Asha S Nair, Shishir Shishodia, Bharat B Aggarwal, 109, 6, 2007-03-15, 2006-12-12, 10.1182/blood-2006-02-003988 10.1182/blood-2006-02-003988 17164350 17164350

Experiments

Compound Experiment type Investigated event Concentration Cell line Organism Animal model Stat protein Details
Resveratrol CCK-8 Influence on cell viability 10.00 µM hFOB 1.19 Homo sapiens
Resveratrol CCK-8 Influence on cell viability 10.00 µM MG-63 Homo sapiens
Resveratrol CCK-8 Influence on cell viability 10.00 µM MNNG/HOS Homo sapiens
Resveratrol CCK-8 Influence on cell viability 20.00 µM hFOB 1.19 Homo sapiens
Resveratrol CCK-8 Influence on cell viability 20.00 µM MG-63 Homo sapiens
Resveratrol CCK-8 Influence on cell viability 20.00 µM MNNG/HOS Homo sapiens
Resveratrol CCK-8 Influence on cell viability 40.00 µM hFOB 1.19 Homo sapiens
Resveratrol CCK-8 Influence on cell viability 40.00 µM MG-63 Homo sapiens
Resveratrol CCK-8 Influence on cell viability 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Tumor volume Influence on cell proliferation in tumor tissue 100.00 mg/kg MG-63 (xenograft) Mus musculus NOD/SCID
Resveratrol Colony formation assay Influence on cell proliferation in tumor tissue 10.00 µM MG-63 Mus musculus
Resveratrol Colony formation assay Influence on cell proliferation 10.00 µM MNNG/HOS Homo sapiens
Resveratrol Colony formation assay Influence on cell proliferation 20.00 µM MG-63 Homo sapiens
Resveratrol Colony formation assay Influence on cell proliferation 20.00 µM MNNG/HOS Homo sapiens
Resveratrol Colony formation assay Influence on cell proliferation 40.00 µM MG-63 Homo sapiens
Resveratrol Colony formation assay Influence on cell proliferation 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Immunofluorescence Influence on cell proliferation 40.00 µM MG-63 Homo sapiens
Resveratrol Immunofluorescence Flow cytometry 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Flow cytometry Flow cytometry 10.00 µM MG-63 Homo sapiens
Resveratrol Flow cytometry Flow cytometry 10.00 µM MNNG/HOS Homo sapiens
Resveratrol Flow cytometry Flow cytometry 20.00 µM MG-63 Homo sapiens
Resveratrol Flow cytometry Flow cytometry 20.00 µM MNNG/HOS Homo sapiens
Resveratrol Flow cytometry Flow cytometry 40.00 µM MG-63 Homo sapiens
Resveratrol Flow cytometry Flow cytometry 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Flow cytometry- annexin V binding and propidium iodide staining Influence on cell apoptosis 40.00 µM MG-63 Homo sapiens
Resveratrol Flow cytometry- annexin V binding and propidium iodide staining Influence on cell apoptosis 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on cell apoptosis 40.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on cell apoptosis 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on cell apoptosis 40.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on cell apoptosis 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on cell apoptosis 40.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on cell apoptosis 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on cell apoptosis 40.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on cell apoptosis 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on cell apoptosis 40.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on cell apoptosis 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on cell apoptosis 40.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on cell apoptosis 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 40.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 40.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 40.00 µM MG-63 Homo sapiens p-STAT3
Resveratrol Western Blot Influence on protien activity 40.00 µM MNNG/HOS Homo sapiens p-STAT3
Resveratrol Western Blot Influence on protien activity 40.00 µM MG-63 Homo sapiens STAT3
Resveratrol Western Blot Influence on protien activity 40.00 µM MNNG/HOS Homo sapiens STAT3
Resveratrol Western Blot Influence on protien activity 40.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 10.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 20.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 40.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 10.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 20.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 10.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 20.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 40.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 10.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 20.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 10.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 20.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 40.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 10.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 20.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 10.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 20.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 40.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 10.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 20.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 10.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 20.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 40.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Influence on protien activity 10.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 20.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Influence on protien activity 40.00 µM MNNG/HOS Homo sapiens
Resveratrol Western Blot Infuence on protein activity in STAT3 transfected cells 40.00 µM MG-63 Homo sapiens STAT3-flag
Resveratrol Western Blot Infuence on protein activity in STAT3 transfected cells 40.00 µM MG-63 Homo sapiens STAT3
Resveratrol Western Blot Infuence on protein activity in STAT3 transfected cells 40.00 µM MG-63 Homo sapiens
Resveratrol Western Blot Infuence on protein activity in STAT3 transfected cells 40.00 µM MG-63 Homo sapiens
Resveratrol CCK-8 Influence on cell viability in STAT3 transfected cells 10.00 µM MG-63 Homo sapiens
Resveratrol CCK-8 Influence on cell viability in STAT3 transfected cells 20.00 µM MG-63 Homo sapiens
Resveratrol CCK-8 Influence on cell viability in STAT3 transfected cells 40.00 µM MG-63 Homo sapiens
Resveratrol Sphere formation Influence on cell proliferation in STAT3 transfected cells 10.00 µM MG-63 Homo sapiens
Resveratrol Sphere formation Influence on cell proliferation in STAT3 transfected cells 20.00 µM MG-63 Homo sapiens
Resveratrol Sphere formation Influence on cell proliferation in STAT3 transfected cells 40.00 µM MG-63 Homo sapiens
Resveratrol Tumor volume Influence on cell proliferation in STAT3 transfected cells in tumor tissue 100.00 mg/kg MG-63 (xenograft) Mus musculus NOD/SCID
Resveratrol MTT Assay Influence on cell proliferation 50.00 µM U266 Homo sapiens
Resveratrol MTT Assay Influence on cell proliferation 50.00 µM MM1 Homo sapiens
Resveratrol MTT Assay Influence on cell proliferation 50.00 µM RPMI 8226 Homo sapiens
Resveratrol Flow cytometry Influence on cell cycle 50.00 µM MM1 Homo sapiens
Resveratrol Western Blot Influence on cell cycle 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on cell cycle 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on cell cycle 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on cell cycle 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on cell cycle 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on cell cycle 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on cell cycle 50.00 µM MM1 Homo sapiens
Resveratrol Western Blot Influence on cell cycle 50.00 µM MM1 Homo sapiens
Resveratrol Western Blot Influence on cell cycle 50.00 µM MM1 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM MM1 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM RPMI 8226 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM RPMI 8226 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM MM1 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM MM1 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM MM1 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM RPMI 8226 Homo sapiens
Resveratrol Western Blot Influence on protein activity 50.00 µM RPMI 8226 Homo sapiens
Resveratrol EMSA Influence on NF-κB protein activity 10.00 µM U266 Homo sapiens
Resveratrol EMSA Influence on NF-κB protein activity 25.00 µM U266 Homo sapiens
Resveratrol EMSA Influence on NF-κB protein activity 50.00 µM U266 Homo sapiens
Resveratrol EMSA Influence on NF-κB protein activity 100.00 µM U266 Homo sapiens
Resveratrol EMSA Influence on NF-κB protein activity 10.00 µM MM1 Homo sapiens
Resveratrol EMSA Influence on NF-κB protein activity 25.00 µM MM1 Homo sapiens
Resveratrol EMSA Influence on NF-κB protein activity 50.00 µM MM1 Homo sapiens
Resveratrol EMSA Influence on NF-κB protein activity 100.00 µM MM1 Homo sapiens
Resveratrol EMSA Influence on NF-κB protein activity 10.00 µM RPMI 8226 Homo sapiens
Resveratrol EMSA Influence on NF-κB protein activity 25.00 µM RPMI 8226 Homo sapiens
Resveratrol EMSA Influence on NF-κB protein activity 50.00 µM RPMI 8226 Homo sapiens
Resveratrol EMSA Influence on NF-κB protein activity 100.00 µM RPMI 8226 Homo sapiens
Resveratrol Western Blot Influence on NF-κB protein activity 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on NF-κB protein activity 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on NF-κB protein activity 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on NF-κB protein activity 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on NF-κB protein activity 50.00 µM U266 Homo sapiens
Resveratrol Western Blot Influence on STAT protein activity 10.00 µM U266 Homo sapiens p-STAT3
Resveratrol Western Blot Influence on STAT protein activity 25.00 µM U266 Homo sapiens p-STAT3
Resveratrol Western Blot Influence on STAT protein activity 50.00 µM U266 Homo sapiens p-STAT3
Resveratrol Western Blot Influence on STAT protein activity 100.00 µM U266 Homo sapiens p-STAT3
Resveratrol Western Blot Influence on STAT protein activity 10.00 µM U266 Homo sapiens STAT3
Resveratrol Western Blot Influence on STAT protein activity 25.00 µM U266 Homo sapiens STAT3
Resveratrol Western Blot Influence on STAT protein activity 50.00 µM U266 Homo sapiens STAT3
Resveratrol Western Blot Influence on STAT protein activity 100.00 µM U266 Homo sapiens STAT3
Resveratrol Western Blot Influence on STAT protein activity 10.00 µM U266 Homo sapiens p-STAT5
Resveratrol Western Blot Influence on STAT protein activity 25.00 µM U266 Homo sapiens p-STAT5
Resveratrol Western Blot Influence on STAT protein activity 50.00 µM U266 Homo sapiens p-STAT5
Resveratrol Western Blot Influence on STAT protein activity 100.00 µM U266 Homo sapiens p-STAT5
Resveratrol Western Blot Influence on STAT protein activity 10.00 µM U266 Homo sapiens STAT5
Resveratrol Western Blot Influence on STAT protein activity 25.00 µM U266 Homo sapiens STAT5
Resveratrol Western Blot Influence on STAT protein activity 50.00 µM U266 Homo sapiens STAT5
Resveratrol Western Blot Influence on STAT protein activity 100.00 µM U266 Homo sapiens STAT5
Resveratrol Western Blot Influence on STAT protein activity in presence IL-6 50.00 µM RPMI 8226 Homo sapiens p-STAT3
Resveratrol Western Blot Influence on STAT protein activity in presence IL-6 50.00 µM RPMI 8226 Homo sapiens STAT3
Resveratrol EMSA Influence on STAT protein activity in presence of Bortezomib 50.00 µM RPMI 8226 Homo sapiens
Resveratrol EMSA Influence on STAT protein activity in presence of Thalidomide 50.00 µM RPMI 8226 Homo sapiens
Resveratrol Western Blot Influence on STAT protein activity in presence of Bortezomib 50.00 µM U266 Homo sapiens p-STAT3
Resveratrol Western Blot Influence on STAT protein activity in presence of Thalidomide 50.00 µM U266 Homo sapiens STAT3
Resveratrol MTT Assay Influence on cell proliferation 10.00 µM Enriched CD138+ Homo sapiens
Resveratrol MTT Assay Influence on cell proliferation 25.00 µM Enriched CD138+ Homo sapiens
Resveratrol MTT Assay Influence on cell proliferation 50.00 µM Enriched CD138+ Homo sapiens
Resveratrol MTT Assay Influence on cell proliferation 100.00 µM Enriched CD138+ Homo sapiens
Resveratrol Flow cytometry- annexin V binding and propidium iodide staining Influence on cell apoposis in presence of Bortezomib 25.00 µM Enriched CD138+ Homo sapiens