PP2

Name Value
Weight 301.781 g/mol
Zinc ID ZINC1383151
Smiles CC(C)(C)n1nc(-c2ccc(Cl)cc2)c2c(N)ncnc21
Molecular formula C15H16ClN5
Mode of inhibition SRC/ STAT3
CAS N/A

Clinical Trials

Study title Status Conditions Link

References

Publication DOI Pubmed PMCID
[Biorhythm of urinary catecholamine excretion in the aged]. Giornale di gerontologia R Scardapane, G M Nardelli, R Giorgino, 17, 12, None, None, 10.3892/ol.2017.5564 10.3892/ol.2017.5564 5403487 PMC5403487

Vendors

Company Lnk to product
Selleckchem https://www.selleckchem.com/products/pp2.html
Sigma Aldrich https://www.sigmaaldrich.com/catalog/product/sigma/p0042?lang=pl&region=PL
MedChemExpress https://www.medchemexpress.com/PP2.html
Abcam https://www.abcam.com/pp2-src-and-rip2-kinase-inhibitor-ab120308.html
Tocris https://www.tocris.com/products/pp-2_1407

Filter data

Compound PP2
Experiment types MTT, Western Blot
Concentrations 10.00, 13.00, 3.00, 30.00, 39.00, 4.00
Cell lines HEK293, T‑47D
Organisms Homo sapiens
Animal models
STAT proteins STAT3, p-STAT3
Other GAPDH, PTK6

Experiments

Compound Experiment type Investigated event Concentration Cell line Organism Animal model Stat protein Details
PP2 Western Blot Influence on protein activity 3.00 nM HEK293 Homo sapiens p-STAT3
PP2 Western Blot Influence on protein activity 10.00 nM HEK293 Homo sapiens p-STAT3
PP2 Western Blot Influence on protein activity 30.00 nM HEK293 Homo sapiens p-STAT3
PP2 Western Blot Influence on protein activity 3.00 nM HEK293 Homo sapiens STAT3
PP2 Western Blot Influence on protein activity 10.00 nM HEK293 Homo sapiens STAT3
PP2 Western Blot Influence on protein activity 30.00 nM HEK293 Homo sapiens STAT3
PP2 Western Blot Influence on protein activity 3.00 nM HEK293 Homo sapiens
PP2 Western Blot Influence on protein activity 10.00 nM HEK293 Homo sapiens
PP2 Western Blot Influence on protein activity 30.00 nM HEK293 Homo sapiens
PP2 Western Blot Influence on protein activity 3.00 nM HEK293 Homo sapiens
PP2 Western Blot Influence on protein activity 10.00 nM HEK293 Homo sapiens
PP2 Western Blot Influence on protein activity 30.00 nM HEK293 Homo sapiens
PP2 MTT Influence on cell growth 4.00 nM T‑47D Homo sapiens
PP2 MTT Influence on cell growth 13.00 nM T‑47D Homo sapiens
PP2 MTT Influence on cell growth 39.00 nM T‑47D Homo sapiens