Methylseleninic Acid
Name | Value |
---|---|
Weight | 127.010 g/mol |
Zinc ID | N/A |
Smiles | C[Se](=O)O |
Molecular formula | CH4O2Se |
Mode of inhibition | JAK and STAT inhibitor; Non-peptide small molecule |
CAS | 28274-57-9 |
Clinical Trials
References
Vendors
Company | Lnk to product |
---|---|
Sigma Aldrich | https://www.sigmaaldrich.com/catalog/product/aldrich/541281?lang=pl®ion=PL |
Filter data
Compound | Methylseleninic Acid |
Experiment types | Flow cytometry- annexin V binding and propidium iodide staining, RT-PCR, RT-qPCR, TUNEL, Tumor volume, Tumor weight, Western Blot |
Concentrations | 1.50, 10.00, 20.00, 5.00 |
Cell lines | 4TI, 4TI (xenograft) |
Organisms | Mus musculus |
Animal models | BALB/c |
STAT proteins | STAT1, STAT2, STAT3, STAT5A, STAT5B, STAT6, p-STAT3 |
Other | Bax, Bcl-2, Caspase-3, Cleaved PARP, Cleaved caspase-3, JAK1, JAK2, JAK3, MMP-2, MMP-9, PARP, TIMP1, TIMP2, XIAP, cXIAP, p-JAK2, β-actin |