Cucurbitacin E |
ELISA |
Influence on pro-inflammatory molecules |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on proteins levels |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on proteins levels |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on proteins levels |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on proteins levels |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on proteins levels |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on proteins levels |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on proteins levels |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Luciferase activity |
Influence on proteins levels |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
p-STAT1 |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
STAT1 |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
p-STAT3 |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
STAT3 |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Luciferase activity |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Luciferase activity |
Influence on protein activity |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Luciferase activity |
Influence on protein activity in transfected cells |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
MTT |
Influence on cell viability |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
TUNEL assay |
Influence on cell viability |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on cell viability |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on cell viability |
0.50 µM |
Microglia |
Homo sapiens |
|
|
|
Cucurbitacin E |
Wound healing assay |
Influence on cell migration |
0.10 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Wound healing assay |
Influence on cell migration |
0.50 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Wound healing assay |
Influence on cell migration |
1.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Wound healing assay |
Influence on cell migration |
10.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Boyden chamber assay |
Influence on cell migration |
0.10 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Boyden chamber assay |
Influence on cell migration |
0.50 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Boyden chamber assay |
Influence on cell migration |
1.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Boyden chamber assay |
Influence on cell migration |
10.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Tubulogenesis |
Influence on cell migration |
0.10 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Tubulogenesis |
Influence on cell migration |
0.50 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Tubulogenesis |
Influence on cell migration |
1.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Tubulogenesis |
Influence on cell migration |
10.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Flow cytometry |
Influence on cell apoptosis |
0.10 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Flow cytometry |
Influence on cell apoptosis |
0.50 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Flow cytometry |
Influence on cell apoptosis |
1.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Flow cytometry |
Influence on cell apoptosis |
10.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Flow cytometry |
Influence on cell apoptosis |
0.10 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Flow cytometry |
Influence on cell apoptosis |
0.50 nM |
PC3 |
|
|
|
|
Cucurbitacin E |
Flow cytometry |
Influence on cell apoptosis |
1.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Flow cytometry |
Influence on cell apoptosis |
10.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Tumor weight |
Influence on tumor growth |
3.00 mg/kg |
PC3(xenograft) |
Mus musculus |
c57BL/6 |
|
|
Cucurbitacin E |
Tumor volume |
Influence on tumor growth |
3.00 mg/kg |
PC3(xenograft) |
Mus musculus |
c57BL/6 |
|
|
Cucurbitacin E |
Body weight |
Influence on tumor growth |
3.00 mg/kg |
PC3(xenograft) |
Mus musculus |
c57BL/6 |
|
|
Cucurbitacin E |
Immunohistochemistry |
Influence on tumor angiogenesis |
3.00 mg/kg |
PC3(xenograft) |
Mus musculus |
c57BL/6 |
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
PC3 |
Homo sapiens |
|
p-STAT3 |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
PC3 |
Homo sapiens |
|
p-STAT3 |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
PC3 |
Homo sapiens |
|
p-STAT3 |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
PC3 |
Homo sapiens |
|
p-STAT3 |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
PC3 |
Homo sapiens |
|
STAT3 |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
PC3 |
Homo sapiens |
|
STAT3 |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
PC3 |
Homo sapiens |
|
STAT3 |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
PC3 |
Homo sapiens |
|
STAT3 |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
PC3 |
Homo sapiens |
|
STAT3(nuclear) |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
PC3 |
Homo sapiens |
|
STAT3(nuclear) |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
PC3 |
Homo sapiens |
|
STAT3(nuclear) |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
PC3 |
Homo sapiens |
|
STAT3(nuclear) |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
PC3 |
Homo sapiens |
|
STAT3(cytoplasmic) |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
PC3 |
Homo sapiens |
|
STAT3(cytoplasmic) |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
PC3 |
Homo sapiens |
|
STAT3(cytoplasmic) |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
PC3 |
Homo sapiens |
|
STAT3(cytoplasmic) |
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Chromatin immunoprecipitation assay |
Influence on protein activity |
0.01 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Chromatin immunoprecipitation assay |
Influence on protein activity |
0.10 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Chromatin immunoprecipitation assay |
Influence on protein activity |
1.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Chromatin immunoprecipitation assay |
Influence on protein activity |
10.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Chromatin immunoprecipitation assay |
Influence on protein activity |
0.01 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Chromatin immunoprecipitation assay |
Influence on protein activity |
0.10 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Chromatin immunoprecipitation assay |
Influence on protein activity |
1.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Chromatin immunoprecipitation assay |
Influence on protein activity |
10.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Chromatin immunoprecipitation assay |
Influence on protein activity |
0.01 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Chromatin immunoprecipitation assay |
Influence on protein activity |
0.10 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Chromatin immunoprecipitation assay |
Influence on protein activity |
1.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Chromatin immunoprecipitation assay |
Influence on protein activity |
10.00 nM |
PC3 |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.01 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
0.10 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
1.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Cucurbitacin E |
Western Blot |
Influence on protein activity |
10.00 nM |
HUVEC |
Homo sapiens |
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