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Compound NCT Number Status Phases Study title Conditions URL
Simvastatin NCT03011931 Completed Early Phase 1 Simvastatin Metabolism as a Test for CD Activity (IRB 15-007568] Celiac Disease https://ClinicalTrials.gov/show/NCT03011931
Simvastatin NCT04178980 Not yet recruiting Phase 1 Role of Simvastatin in Relapsing-Remitting Multiple Sclerosis Simvastatin Multiple Sclerosis https://ClinicalTrials.gov/show/NCT04178980
Simvastatin NCT03324425 Recruiting Phase 2 Simvastatin Plus Dual Anti-HER2 Therapy for Metastatic Breast Cancer Breast Cancer Stage IV https://ClinicalTrials.gov/show/NCT03324425
Simvastatin NCT01702246 Completed Phase 1|Phase 2 Effect of Simvastatin Treatment on Vaso-occlusive Pain in Sickle Cell Disease Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01702246
Simvastatin NCT04183387 Completed Phase 2 Simvastatin in Uveitis Uveitis https://ClinicalTrials.gov/show/NCT04183387
Simvastatin NCT02061397 Active, not recruiting Phase 1|Phase 2 Safety of Simvastatin in LAM and TSC Lymphangioleiomyomatosis|Tuberous Sclerosis Complex https://ClinicalTrials.gov/show/NCT02061397
Simvastatin NCT01771198 Terminated Phase 2 Efficacy Study of SIMVASTATIN to Treat Chronic Rhinosinusitis After Failure of Optimal Treatment Rhinosinusitis https://ClinicalTrials.gov/show/NCT01771198
Simvastatin NCT02096588 Active, not recruiting Phase 2 Detection and Prevention of Anthracycline-Related Cardiac Toxicity With Concurrent Simvastatin Breast Cancer|Stage I Breast Cancer|Stage II Breast Cancer|Stage III Breast Cancer https://ClinicalTrials.gov/show/NCT02096588
Simvastatin NCT03896217 Recruiting Phase 2 Simvastatin in Secondary Progressive Multiple Sclerosis Secondary Progressive Multiple Sclerosis https://ClinicalTrials.gov/show/NCT03896217
Simvastatin NCT03329118 Unknown status Phase 1 Drug-drug Interaction Between Simvastatin and SHR3824 Type 2 Diabetes https://ClinicalTrials.gov/show/NCT03329118
Simvastatin NCT02197234 Active, not recruiting Phase 1 Study to Assess the Effect of AZD9291 on the Blood Levels of Simvastatin in Patients With EGFRm+ NSCLC Non Small Cell Lung Cancer https://ClinicalTrials.gov/show/NCT02197234
Simvastatin NCT03131726 Recruiting Phase 3 Treatment of Graves´Ophthalmopathy With Simvastatin (GO-DS) Graves Ophthalmopathy|Thyroid Associated Ophthalmopathy|Thyroid Associated Orbitopathy https://ClinicalTrials.gov/show/NCT03131726
Simvastatin NCT01160978 Completed Phase 2|Phase 3 Donor Simvastatin Treatment in Organ Transplantation Heart Failure|Respiratory Failure|Liver Failure|Kidney Failure|Transplantation https://ClinicalTrials.gov/show/NCT01160978
Simvastatin NCT01266434 Completed Phase 3 The Additive Anti-inflammatory Effect of Simvastatin in Combination With Inhaled Corticosteroids on p38 MAPK in Asthma Asthma https://ClinicalTrials.gov/show/NCT01266434
Simvastatin NCT02433535 Withdrawn Phase 2 Trial of Simvastatin for the Treatment of Severe Asthma Severe Asthma https://ClinicalTrials.gov/show/NCT02433535
Simvastatin NCT02161822 Active, not recruiting Phase 2 Capecitabine Plus Simvastatin in Locally Advanced Rectal Cancer Patients Adenocarcinoma of Rectum https://ClinicalTrials.gov/show/NCT02161822
Simvastatin NCT03247400 Unknown status Phase 1|Phase 2 The Evaluation of Vitiligous Lesions Repigmentation After the Administration of Atorvastatin Calcium Salt and Simvastatin-acid Sodium Salt in Patients With Active Vitiligo Non-segmental Vitiligo https://ClinicalTrials.gov/show/NCT03247400
Simvastatin NCT01561482 Withdrawn Phase 2 Study of Metformin With Simvastatin for Men With Prostate Carcinoma Prostate Carcinoma https://ClinicalTrials.gov/show/NCT01561482
Simvastatin NCT03775070 Recruiting Phase 2 Simvastatin Therapy in Patients With Dilated Cardiomyopathy. Dilated Cardiomyopathy https://ClinicalTrials.gov/show/NCT03775070
Simvastatin NCT03571802 Not yet recruiting Phase 4 Pharmacokinetics of Simvastatin Post Laparoscopic Sleeve Gastrectomy (LSG) Obesity|Hyperlipidemias https://ClinicalTrials.gov/show/NCT03571802
Simvastatin NCT02946424 Recruiting Phase 2 Simvastatin to Prevent SCI-Induced Bone Loss Spinal Cord Injuries|Osteoporosis https://ClinicalTrials.gov/show/NCT02946424
Simvastatin NCT01073007 Completed Phase 4 Stroke Treatment With Acute Reperfusion and Simvastatin Stroke, Acute https://ClinicalTrials.gov/show/NCT01073007
Simvastatin NCT02815722 Completed Phase 1 The Drug-drug Interaction of SP2086 and Simvastatin Type 2 Diabetes https://ClinicalTrials.gov/show/NCT02815722
Simvastatin NCT04301271 Recruiting Phase 2 Simvastatin add-on Treatment to Standard Antidepressant Therapy in Patients With Comorbid Obesity and Major Depression Depressive Disorder, Major|Obesity https://ClinicalTrials.gov/show/NCT04301271
Simvastatin NCT03654053 Not yet recruiting Phase 3 Multi-Center Study of the Effects of Simvastatin on Hepatic Decompensation and Death in Subjects Presenting With High-Risk Compensated Cirrhosis Cirrhosis https://ClinicalTrials.gov/show/NCT03654053
Simvastatin NCT03402204 Completed Phase 3 Efficacy of High and Low-Dose Simvastatin on Vascular Oxidative Stress and Neurological Outcome in Patients With AIS Ischemic Stroke https://ClinicalTrials.gov/show/NCT03402204
Simvastatin NCT04021498 Recruiting Phase 3 Simvastatin in the Prevention of Recurrent Pancreatitis Pancreatitis Relapsing https://ClinicalTrials.gov/show/NCT04021498
Simvastatin NCT01654562 Terminated Phase 1|Phase 2 The Short-term Effects of Simvastatin on the Vision of Males Affected by Choroideremia Choroideremia https://ClinicalTrials.gov/show/NCT01654562
Simvastatin NCT01821027 Completed Phase 1 A Study to Assess the Effects of Canagliflozin (JNJ-28431754) on the Pharmacokinetics, Pharmacodynamics, and Safety of Simvastatin in Healthy Volunteers Healthy https://ClinicalTrials.gov/show/NCT01821027
Simvastatin NCT01147692 Completed Phase 1 A Drug Interaction Study of Simvastatin and Albiglutide Diabetes Mellitus, Type 2 https://ClinicalTrials.gov/show/NCT01147692
Simvastatin NCT01952288 Completed Phase 4 Simvastatin for mTBI TBI-Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT01952288
Simvastatin NCT04044417 Completed Phase 4 Curcumin-Simvastatin-EDTA in the Treatment of Periodontitis Periodontitis https://ClinicalTrials.gov/show/NCT04044417
Simvastatin NCT03400475 Completed Phase 2 Use of Topical Subgingival Application of Simvastatin Gel in the Treatment of Peri-Implant Mucositis Peri-implant Mucositis https://ClinicalTrials.gov/show/NCT03400475
Simvastatin NCT03403972 Completed Phase 1 Evaluate the Effects of the Environmental Change in Intestine by Antibiotics on the Pharmacokinetic Characteristics of Simvastatin in Healthy Male Volunteers Simvastatin Pharmacokinetics and Gut Microbiome https://ClinicalTrials.gov/show/NCT03403972
Simvastatin NCT03086291 Recruiting Phase 1 A Phase I Study of High Dose Simvastatin in Patients With Gastrointestinal Tract Cancer Who Failed to Standard Chemotherapy Stomach Cancer https://ClinicalTrials.gov/show/NCT03086291
Simvastatin NCT02817243 Unknown status Phase 1 The DDI Study of SP2086 and Simvastatin Type 2 Diabetes https://ClinicalTrials.gov/show/NCT02817243
Simvastatin NCT01960140 Completed Phase 1 A Study of Baricitinib and Simvastatin in Healthy Participants Healthy Volunteers https://ClinicalTrials.gov/show/NCT01960140
Simvastatin NCT03400826 Recruiting Phase 2 Effects of Simvastatin on Uterine Leiomyoma Size Fibroid Uterus|Fibroid Tumor|Leiomyoma|Fibromyoma|Leiomyoma, Uterine https://ClinicalTrials.gov/show/NCT03400826
Simvastatin NCT02447601 Completed Phase 1 Evaluate the Pharmacokinetics of Simvastatin When Coadministered With PEX168 in Healthy Adult Subjects Type 2 Diabetes Mellitus https://ClinicalTrials.gov/show/NCT02447601
Simvastatin NCT01642862 Terminated Phase 1 Study for Identifying Optimal Simvastatin Formulation for Uniform Time to Maximum Plasma Concentration Celiac Disease https://ClinicalTrials.gov/show/NCT01642862
Simvastatin NCT02548936 Unknown status Early Phase 1 Efficacy and Safety of Simvastatin-ezetimibe Combination Therapy Among Patients With SLE Atherosclerosis https://ClinicalTrials.gov/show/NCT02548936
Simvastatin NCT01167933 Completed Phase 1 Bioequivalence Study of Simvastatin Tablets, 80 mg of Dr. Reddy's Under Fed Conditions Healthy https://ClinicalTrials.gov/show/NCT01167933
Simvastatin NCT01167894 Completed Phase 1 Bioequivalence Study of Simvastatin Tablets 80 mg of Dr. Reddy's Under Fasting Condition Healthy https://ClinicalTrials.gov/show/NCT01167894
Simvastatin NCT03771053 Recruiting Not Applicable The Effect of Simvastatin Combined With Ezetimibe in Patients With Stable Angina and Diabetes Coronary Heart Disease https://ClinicalTrials.gov/show/NCT03771053
Simvastatin NCT01999309 Unknown status Phase 3 Simvastatin Addition for Patients With Recent-onset Schizophrenia Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder|Psychosis NOS https://ClinicalTrials.gov/show/NCT01999309
Simvastatin NCT03387670 Recruiting Phase 3 Multiple Sclerosis-Simvastatin Trial 2 Secondary Progressive Multiple Sclerosis (SPMS) https://ClinicalTrials.gov/show/NCT03387670
Simvastatin NCT00994773 Completed Phase 1 Simvastatin for the Treatment of Chronic Hepatitis B Hepatitis B https://ClinicalTrials.gov/show/NCT00994773
Simvastatin NCT03419429 Completed Phase 4 Simvastatin Gel With Perforated Resorbable Membranes in Treatment of Intrabony Defects in Chronic Periodontitis Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03419429
Simvastatin NCT00935259 Completed Phase 1 Lipid Biomarker Study in Men With Dyslipidemia After Simvastatin Treatment (Study MK-0000-140)(COMPLETED) Hypercholesterolemia, Dyslipidemia https://ClinicalTrials.gov/show/NCT00935259
Simvastatin NCT02886299 Completed Phase 4 Randomized Comparative Efficacy and Safety Study of Intermittent Simvastatin and Fenofibrate in Hemodialysis Fenofibrate/Simvastatin Comparison https://ClinicalTrials.gov/show/NCT02886299