| Methotrexate |
NCT03757364 |
Completed |
N/A |
Methotrexate in the Treatment of Distal Interphalangeal Joint Extensor Tendon Enthesopathy in Nail Psoriasis |
Nail Psoriasis |
https://ClinicalTrials.gov/show/NCT03757364 |
| Methotrexate |
NCT04299971 |
Recruiting |
Phase 4 |
Efficiency of Methotrexate and Tofacitinib in Mild and Moderate Patients |
Takayasu Arteritis|Methotrexate|Inhibition|Treatment |
https://ClinicalTrials.gov/show/NCT04299971 |
| Methotrexate |
NCT03414502 |
Recruiting |
Phase 3 |
Treatment of Rheumatoid Arthritis With Methotrexate: Predictors of Response |
Rheumatoid Arthritis |
https://ClinicalTrials.gov/show/NCT03414502 |
| Methotrexate |
NCT02076997 |
Unknown status |
Not Applicable |
Individualized High Dose Methotrexate to Treat Cancer in Children Who Have a Significant Risk for Side Effects to Methotrexate |
Cancer |
https://ClinicalTrials.gov/show/NCT02076997 |
| Methotrexate |
NCT02037191 |
Completed |
Phase 3 |
The Efficiency Of The Methotrexate At Patients Affected By Grave Pelade |
ALOPECIA AREATA |
https://ClinicalTrials.gov/show/NCT02037191 |
| Methotrexate |
NCT02940561 |
Unknown status |
Phase 1 |
BE Study in Patients - Methotrexate Tablets |
Psoriasis|Rheumatoid Arthritis |
https://ClinicalTrials.gov/show/NCT02940561 |
| Methotrexate |
NCT04205734 |
Not yet recruiting |
N/A |
Methotrexate Polyglutamate Measurements in Patients With Inflammatory Bowel Disease |
IBD |
https://ClinicalTrials.gov/show/NCT04205734 |
| Methotrexate |
NCT00791531 |
Completed |
Phase 1 |
Assessment of Safety and Pharmacokinetics of a Low Dose of Methotrexate in Healthy Adult Male Kenyan Volunteers |
Malaria |
https://ClinicalTrials.gov/show/NCT00791531 |
| Methotrexate |
NCT02553018 |
Completed |
Phase 3 |
Comparison of Compliance and Evolution of Functional Capacity of Patients With Rheumatoid Arthritis Treated by Methotrexate Either by Auto-injector or by Conventional Sub-cutaneous Syringe |
Arthritis, Rheumatoid |
https://ClinicalTrials.gov/show/NCT02553018 |
| Methotrexate |
NCT02714634 |
Unknown status |
Phase 4 |
Clinical Trial Evaluating Methotrexate + Biologic Versus Methotrexate, Salazopyrine and Hydroxychloroquine in Patients With Rheumatoid Arthritis and Insufficient Response to Methotrexate |
Rheumatoid Arthritis|Insufficient Response to Methotrexate. |
https://ClinicalTrials.gov/show/NCT02714634 |
| Methotrexate |
NCT03123718 |
Not yet recruiting |
Phase 3 |
High-dose Intravenous Methotrexate Versus Intrathecal Methotrexate for Central Nervous System Prophylaxis in DLBCL |
DLBCL |
https://ClinicalTrials.gov/show/NCT03123718 |
| Methotrexate |
NCT02269358 |
Completed |
Phase 4 |
Salvage Therapy With High/Low Methotrexate for Loss of Response to Infliximab Dose Escalation |
Crohn's Disease |
https://ClinicalTrials.gov/show/NCT02269358 |
| Methotrexate |
NCT01884636 |
Completed |
Phase 1 |
A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Methotrexate |
Pharmacokinetics of Isavuconazole|Pharmacokinetics of Methotrexate|Pharmacokinetics of 7-hydroxymethotrexate|Healthy Subjects |
https://ClinicalTrials.gov/show/NCT01884636 |
| Methotrexate |
NCT02124226 |
Not yet recruiting |
Phase 3 |
Low-dose Methotrexate for Change in Global Initiative for Asthma Step 5 Medications in Chronic Severe Asthma |
Low Dose Methotrexate in Severe Chronic Asthma |
https://ClinicalTrials.gov/show/NCT02124226 |
| Methotrexate |
NCT02715947 |
Unknown status |
Phase 2 |
Pharmacogenomics Study on Treatment of Psoriasis Vulgaris by Methotrexate |
Psoriasis Vulgaris |
https://ClinicalTrials.gov/show/NCT02715947 |
| Methotrexate |
NCT02772965 |
Recruiting |
Phase 3 |
Low Dose Oral Methotrexate in Pediatric Crohn's Disease Patients Initiating Anti-Tumor Necrosis Factor (Anti-TNF) Therapy |
Pediatric Crohn's Disease |
https://ClinicalTrials.gov/show/NCT02772965 |
| Methotrexate |
NCT03408756 |
Unknown status |
Phase 4 |
Comparison of Oral Versus Subcutaneous Route of Methotrexate Administration in Moderate to Severe Psoriasis |
Psoriasis Vulgaris |
https://ClinicalTrials.gov/show/NCT03408756 |
| Methotrexate |
NCT02528435 |
Completed |
N/A |
Understanding Methotrexate Induced Gastrointestinal Intolerance in Juvenile Idiopathic Arthritis and Childhood Leukemia |
Juvenile Idiopathic Arthritis|ALL |
https://ClinicalTrials.gov/show/NCT02528435 |
| Methotrexate |
NCT02174354 |
Unknown status |
N/A |
Methotrexate Polyglutamates as a Marker of Clinical Response and Toxicity in the Treatment of Psoriasis |
Psoriasis Chronic|Injury of Liver |
https://ClinicalTrials.gov/show/NCT02174354 |
| Methotrexate |
NCT03852888 |
Recruiting |
Not Applicable |
Kinetics of Elimination of Methotrexate and Its Major Metabolite 7-OH-methotrexate for Observant Patients |
Rheumatoid Arthritis |
https://ClinicalTrials.gov/show/NCT03852888 |
| Methotrexate |
NCT01737671 |
Completed |
Early Phase 1 |
Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study |
Brain Tumor|Malignant Neoplasm of Fourth Ventricle of Brain |
https://ClinicalTrials.gov/show/NCT01737671 |
| Methotrexate |
NCT02591823 |
Unknown status |
N/A |
Hair Fall in Patients on Low Dose Methotrexate |
Alopecia|Rheumatoid Arthritis|Methotrexate Adverse Reaction |
https://ClinicalTrials.gov/show/NCT02591823 |
| Methotrexate |
NCT02644044 |
Unknown status |
Early Phase 1 |
Intrathecal Methotrexate for Progressive Multiple Sclerosis: An Open Label Single Arm Study |
To Evaluate the Effect of Therapy With IT MTX on the Disease Course of Patients With Progressive MS |
https://ClinicalTrials.gov/show/NCT02644044 |
| Methotrexate |
NCT03904680 |
Not yet recruiting |
Phase 4 |
Studying the Effect of Methotrexate Alone Versus Methotrexate and Vitamin D on the Cardiovascular Risk of Psoriatic Patients |
Psoriasis |
https://ClinicalTrials.gov/show/NCT03904680 |
| Methotrexate |
NCT02905110 |
Recruiting |
Early Phase 1 |
Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children With Recurrent Posterior Fossa Brain Tumors |
Brain Tumor Recurrent |
https://ClinicalTrials.gov/show/NCT02905110 |
| Methotrexate |
NCT04196920 |
Recruiting |
N/A |
Methotrexate-associated Anti-TNF Combination Therapy, the Neglected One ! |
Chronic Inflammatory Bowel Disease |
https://ClinicalTrials.gov/show/NCT04196920 |
| Methotrexate |
NCT01633983 |
Unknown status |
Phase 2 |
Methotrexate for Central Serous Chorioretinopathy Treatment Trial |
Central Serous Chorioretinopathy |
https://ClinicalTrials.gov/show/NCT01633983 |
| Methotrexate |
NCT03736161 |
Completed |
Phase 3 |
Safety and Efficacy of Tofacitinib vs Methotrexate in the Treatment of Psoriatic Arthritis |
Psoriatic Arthritis |
https://ClinicalTrials.gov/show/NCT03736161 |
| Methotrexate |
NCT01438021 |
Withdrawn |
Not Applicable |
Continuous Intraventricular Methotrexate in Treating Patients With Leptomeningeal Disease |
Leptomeningeal Metastases |
https://ClinicalTrials.gov/show/NCT01438021 |
| Methotrexate |
NCT04177173 |
Completed |
Phase 4 |
Methotrexate and Statins With Methotrexate Alone in the Treatment of Rheumatoid Arthritis |
Arthritis, Rheumatoid |
https://ClinicalTrials.gov/show/NCT04177173 |
| Methotrexate |
NCT02764515 |
Unknown status |
Phase 4 |
Kunxian for the Treatment of Rheumatoid Arthritis |
Rheumatoid Arthritis |
https://ClinicalTrials.gov/show/NCT02764515 |
| Methotrexate |
NCT04247815 |
Recruiting |
Phase 2 |
Study of ATI-450 Plus Methotrexate (MTX) vs MTX Alone in Patients With Moderate to Severe RA |
Rheumatoid Arthritis |
https://ClinicalTrials.gov/show/NCT04247815 |
| Methotrexate |
NCT02867306 |
Completed |
Phase 1 |
A Study to Evaluate the Pharmacokinetics of ASP1707 and Methotrexate in Patients With Rheumatoid Arthritis |
Rheumatoid Arthritis |
https://ClinicalTrials.gov/show/NCT02867306 |
| Methotrexate |
NCT04311567 |
Not yet recruiting |
Phase 4 |
Effects of Tofacitinib vs Methotrexate on Rheumatoid Arthritis Interstitial Lung Disease |
Rheumatoid Arthritis|Interstitial Lung Disease Due to Systemic Disease (Disorder)|RA|ILD |
https://ClinicalTrials.gov/show/NCT04311567 |
| Methotrexate |
NCT03815448 |
Recruiting |
Not Applicable |
Methotrexate in the Treatment of Advanced Knee Osteoarthritis With Effusion-synovitis |
Knee Osteoarthritis|Effusion Synovial|Knee Pain |
https://ClinicalTrials.gov/show/NCT03815448 |
| Methotrexate |
NCT00779142 |
Terminated |
Not Applicable |
Utility of Intravitreal Methotrexate in Diabetic Macular Edema Resistant to Conventional Therapies |
Diabetic Macular Edema |
https://ClinicalTrials.gov/show/NCT00779142 |
| Methotrexate |
NCT03348670 |
Active, not recruiting |
Phase 3 |
Discovery Stage IND EXEMPT Clinical Study - Etoposide OS Plus Methotrexate OS and Single Nucleotide Polymorphisms |
Small Cell Lung Cancer |
https://ClinicalTrials.gov/show/NCT03348670 |
| Methotrexate |
NCT01414257 |
Completed |
N/A |
Methotrexate (Rheumatrex) High Dose Special Investigation (Regulatory Post Marketing Commitment Plan) |
Arthritis|Rheumatoid|High Dose |
https://ClinicalTrials.gov/show/NCT01414257 |
| Methotrexate |
NCT01741558 |
Unknown status |
Phase 2 |
The Effects of mETHotrexate Therapy on ST Segment Elevation MYocardial InfarctionS (TETHYS Trial) |
Myocardial Infarction |
https://ClinicalTrials.gov/show/NCT01741558 |
| Methotrexate |
NCT02373579 |
Completed |
Phase 2 |
Effect of Omega-3 Fatty Acids on Methotrexate Induced Hepatotoxicity in Children With Acute Lymphoblastic Leukemia |
Acute Lymphoblastic Leukemia |
https://ClinicalTrials.gov/show/NCT02373579 |
| Methotrexate |
NCT00579644 |
Completed |
Phase 3 |
Treatment of Early RA: Minocycline in Combination With Methotrexate vs Methotrexate Alone |
Rheumatoid Arthritis |
https://ClinicalTrials.gov/show/NCT00579644 |
| Methotrexate |
NCT02684071 |
Terminated |
Phase 2 |
Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors |
Recurrent Childhood Medulloblastoma|Recurrent Childhood Ependymoma|Childhood Atypical Teratoid/Rhabdoid Tumor|Embryonal Tumor With Abundant Neuropil and True Rosettes|Metastatic Malignant Neoplasm to the Leptomeninges |
https://ClinicalTrials.gov/show/NCT02684071 |
| Methotrexate |
NCT01855568 |
Completed |
Phase 3 |
Methotrexate Treatment for Ectopic Pregnancy |
Ectopic Pregnancy |
https://ClinicalTrials.gov/show/NCT01855568 |
| Methotrexate |
NCT02714998 |
Completed |
Not Applicable |
The Impact of Salpingectomy and Single Dose Systemic Methotrexate Treatments on Ovarian Reserve in Ectopic Pregnancy |
Ectopic Pregnancy|Infertility |
https://ClinicalTrials.gov/show/NCT02714998 |
| Methotrexate |
NCT02074319 |
Completed |
Phase 1 |
RCT of Methotrexate Added to Treatment As Usual in Schizophrenia |
Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder |
https://ClinicalTrials.gov/show/NCT02074319 |
| Methotrexate |
NCT04237103 |
Not yet recruiting |
Phase 2 |
Combination of Methotrexate and Phototherapy Versus Phototherapy in Adults With Progressive Vitiligo |
Vitiligo |
https://ClinicalTrials.gov/show/NCT04237103 |
| Methotrexate |
NCT01942174 |
Active, not recruiting |
Phase 3 |
VACcination In Methotrexate Treated Rheumatoid Arthritis Patients |
Rheumatoid Arthritis |
https://ClinicalTrials.gov/show/NCT01942174 |
| Methotrexate |
NCT02196701 |
Completed |
Phase 3 |
Concomitant Longitudinal Evaluation of Adalimumab With Methotrexate in the Real World: the CLEAR Study |
Psoriasis |
https://ClinicalTrials.gov/show/NCT02196701 |
| Methotrexate |
NCT02277444 |
Active, not recruiting |
Phase 3 |
A Study to Evaluate the Pharmacokinetics, Efficacy and Safety of Intravenous Golimumab in Pediatric Participants With Active Polyarticular Course Juvenile Idiopathic Arthritis Despite Methotrexate Therapy |
Arthritis, Juvenile |
https://ClinicalTrials.gov/show/NCT02277444 |
| Methotrexate |
NCT01927484 |
Not yet recruiting |
Not Applicable |
Hand OA AND Methotrexate Use |
Reduction in Pain|Reduction of Inflammation|Improvement in Function |
https://ClinicalTrials.gov/show/NCT01927484 |
