Investigated event: Influence on neuronal apoptosis

Name Value
Compound AG490
Investigated event Influence on neuronal apoptosis
Experiment type TUNEL
Concentration 10.00 µM
Cell line Brain tissue
Organism Rattus norvegicus
Animal model Sprague-Dawley (SD) rats
STAT protein
Other
Reference
AG490 ameliorates early brain injury via inhibition of JAK2/STAT3-mediated regulation of HMGB1 in subarachnoid hemorrhage. Experimental and therapeutic medicine Ji-Yang An, Hong-Gang Pang, Ting-Qin Huang, Jin-Ning Song, Dan-Dong Li, Yong-Lin Zhao, Xu-Dong Ma, 15, 2, None, 2017-11-22, 10.3892/etm.2017.5539 DOI: 10.3892/etm.2017.5539 PUBMED: 29434719 PMCID: PMC5774435