Investigated event: Influence on protein activity in presence of CLI and/or EPO

Name Value
Compound AG490
Investigated event Influence on protein activity in presence of CLI and/or EPO
Experiment type Western Blot
Concentration 3.00 mg/kg
Cell line quadriceps
Organism Rattus norvegicus
Animal model Sprague-Dawley (SD) rats
STAT protein
Other Akt
Reference
AG490 suppresses EPO-mediated activation of JAK2-STAT but enhances blood flow recovery in rats with critical limb ischemia. Journal of inflammation (London, England) Han-Tan Chai, Hon-Kan Yip, Cheuk-Kwan Sun, Shu-Yuan Hsu, Steve Leu, 13, None, None, 2016-06-04, 10.1186/s12950-016-0126-3 DOI: 10.1186/s12950-016-0126-3 PUBMED: 27274711 PMCID: PMC4893245