Investigated event: Influence on protein activity in tumor tissue

Name Value
Compound SD-91
Investigated event Influence on protein activity in tumor tissue
Experiment type Western Blot
Concentration 50.00 mg/kg
Cell line SU-DHL-1(xenograft)
Organism Mus musculus
Animal model
STAT protein p-STAT3(Y705)
Other
Reference
SD-91 as A Potent and Selective STAT3 Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression. ACS medicinal chemistry letters Haibin Zhou, Longchuan Bai, Renqi Xu, Donna McEachern, Krishnapriya Chinnaswamy, Ruiting Li, Bo Wen, Mi Wang, Chao-Yie Yang, Jennifer L Meagher, Duxin Sun, Jeanne A Stuckey, Shaomeng Wang, 12, 6, 2021-06-10, 2021-05-10, 10.1021/acsmedchemlett.1c00155 DOI: 10.1021/acsmedchemlett.1c00155 PUBMED: 34141084 PMCID: PMC8201759