Investigated event:

Name Value
Compound Atiprimod
Investigated event
Experiment type DNA Fragmentation Assay
Concentration 2.50 µM
Cell line HepG2
Organism Homo sapiens
Animal model
STAT protein
Other Caspase-3/7
Reference
Deactivation of Akt and STAT3 signaling promotes apoptosis, inhibits proliferation, and enhances the sensitivity of hepatocellular carcinoma cells to an anticancer agent, Atiprimod. Molecular cancer therapeutics Sweeta R Choudhari, Muhammad A Khan, Genesis Harris, Donald Picker, Gary S Jacob, Timothy Block, Kunwar Shailubhai, 6, 1, None, None, 10.1158/1535-7163.MCT-06-0561 DOI: 10.1158/1535-7163.MCT-06-0561 PUBMED: 17237271 PMCID: 17237271