MLS-2384

Name Value
Weight 468.355 g/mol
Zinc ID ZINC40956135
Smiles O=C1Nc2cc(Br)ccc2/C1=C1/Nc2ccccc2/C1=N\OCCN1CCNCC1
Molecular formula C22H22BrN5O2
Mode of inhibition SRC, JAK, STAT inhibitor;
CAS 1067884-45-0

Clinical Trials

Study title Status Conditions Link

References

Publication DOI Pubmed PMCID
A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone. The New England journal of medicine S A Rosenberg, M T Lotze, L M Muul, A E Chang, F P Avis, S Leitman, W M Linehan, C N Robertson, R E Lee, J T Rubin, 316, 15, 1987-04-09, None, 10.4161/cbt.21781 10.4161/cbt.21781 3493432 22895078
MLS-2384, a new 6-bromoindirubin derivative with dual JAK/Src kinase inhibitory activity, suppresses growth of diverse cancer cells. Cancer biology & therapy Lucy Liu, Nicolas Gaboriaud, Konstantina Vougogianopoulou, Yan Tian, Jun Wu, Wei Wen, Leandros Skaltsounis, Richard Jove, 15, 2, None, 2013-11-01, 10.4161/cbt.26721 10.4161/cbt.26721 24100507 PMC3928133

Vendors

Company Lnk to product
MedKoo Biosciences https://www.medkoo.com/products/29669

Filter data

Compound MLS-2384
Experiment types Body weight, Flow Cytometry Annexin, MTS, MTT, Tumor volume, Western Blot
Concentrations 1.00, 10.00, 100.00, 2.50, 20.00, 25.00, 5.00, 50.00
Cell lines A2058, A2058 (xenograft), A2780, A375, A549, DU145, G361, HepG2, MDA-MB-468, MeWo , MeWo (xenograft), NHFD
Organisms Homo sapiens, Mus musculus
Animal models BALB/c, NSG
STAT proteins STAT3, p-STAT3
Other Akt, Bad, Bak, Bax, Bcl-2, Bid, Bim, Caspase-3, Celaved PARP, ERK1/2, JAK2, Mcl-1, PARP, Src, Survivin, c-Myc, p-Akt, p-ERK1/2, p-Jak2, p-Src, β-actin

Experiments

Compound Experiment type Investigated event Concentration Cell line Organism Animal model Stat protein Details
MLS-2384 Tumor volume Influence on tumor growth 50.00 mg/kg MeWo (xenograft) Mus musculus NSG
MLS-2384 Body weight Influence on tumor growth 50.00 mg/kg MeWo (xenograft) Mus musculus NSG
MLS-2384 MTT Influence on cell prolifration 1.00 µM A2058 Homo sapiens
MLS-2384 MTT Influence on cell prolifration 2.50 µM A2058 Homo sapiens
MLS-2384 MTT Influence on cell prolifration 5.00 µM A2058 Homo sapiens
MLS-2384 MTT Influence on cell prolifration 1.00 µM A375 Homo sapiens
MLS-2384 MTT Influence on cell prolifration 2.50 µM A375 Homo sapiens
MLS-2384 MTT Influence on cell prolifration 5.00 µM A375 Homo sapiens
MLS-2384 MTT Influence on cell prolifration 1.00 µM G361 Homo sapiens
MLS-2384 MTT Influence on cell prolifration 2.50 µM G361 Homo sapiens
MLS-2384 MTT Influence on cell prolifration 5.00 µM G361 Homo sapiens
MLS-2384 MTT Influence on cell prolifration 1.00 µM MeWo Homo sapiens
MLS-2384 MTT Influence on cell prolifration 2.50 µM MeWo Homo sapiens
MLS-2384 MTT Influence on cell prolifration 5.00 µM MeWo Homo sapiens
MLS-2384 Flow Cytometry Annexin Influence on cell apoptosis 1.00 µM A2058 Homo sapiens
MLS-2384 Flow Cytometry Annexin Influence on cell apoptosis 2.50 µM A2058 Homo sapiens
MLS-2384 Flow Cytometry Annexin Influence on cell apoptosis 5.00 µM A2058 Homo sapiens
MLS-2384 Flow Cytometry Annexin Influence on cell apoptosis 1.00 µM A375 Homo sapiens
MLS-2384 Flow Cytometry Annexin Influence on cell apoptosis 2.50 µM A375 Homo sapiens
MLS-2384 Flow Cytometry Annexin Influence on cell apoptosis 5.00 µM A375 Homo sapiens
MLS-2384 Flow Cytometry Annexin Influence on cell apoptosis 1.00 µM G361 Homo sapiens
MLS-2384 Flow Cytometry Annexin Influence on cell apoptosis 2.50 µM G361 Homo sapiens
MLS-2384 Flow Cytometry Annexin Influence on cell apoptosis 5.00 µM G361 Homo sapiens
MLS-2384 Flow Cytometry Annexin Influence on cell apoptosis 1.00 µM MeWo Homo sapiens
MLS-2384 Flow Cytometry Annexin Influence on cell apoptosis 2.50 µM MeWo Homo sapiens
MLS-2384 Flow Cytometry Annexin Influence on cell apoptosis 5.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 5.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 5.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 5.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell survival 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 1.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 2.50 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 1.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 2.50 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 1.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell survival 2.50 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell survival 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 1.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 2.50 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 1.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 2.50 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 1.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell survival 2.50 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell survival 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 1.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 2.50 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 1.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 2.50 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 1.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell survival 2.50 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell survival 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 1.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 2.50 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 1.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 2.50 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on cell survival 1.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on cell survival 2.50 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 5.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 5.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 5.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 5.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 5.00 µM A2058 Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 10.00 µM A2058 Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 5.00 µM A2058 Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 10.00 µM A2058 Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 5.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 5.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 5.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 5.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 5.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A375 Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 10.00 µM G361 Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 10.00 µM MeWo Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 10.00 µM A375 Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 10.00 µM G361 Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 10.00 µM MeWo Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 10.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM A375 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM G361 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 10.00 µM MeWo Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM MDA-MB-468 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM MDA-MB-468 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2780 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2780 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A549 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A549 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM MDA-MB-468 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM MDA-MB-468 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2780 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2780 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A549 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A549 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM MDA-MB-468 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM MDA-MB-468 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2780 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2780 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A549 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A549 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM MDA-MB-468 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM MDA-MB-468 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2780 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2780 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A549 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A549 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM DU145 Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 2.50 µM DU145 Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 1.00 µM MDA-MB-468 Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 2.50 µM MDA-MB-468 Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2780 Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2780 Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 1.00 µM A549 Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 2.50 µM A549 Homo sapiens p-STAT3
MLS-2384 Western Blot Influence on protein activity 1.00 µM DU145 Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 2.50 µM DU145 Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 1.00 µM MDA-MB-468 Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 2.50 µM MDA-MB-468 Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2780 Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2780 Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 1.00 µM A549 Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 2.50 µM A549 Homo sapiens STAT3
MLS-2384 Western Blot Influence on protein activity 1.00 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM MDA-MB-468 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM MDA-MB-468 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A2780 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A2780 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 1.00 µM A549 Homo sapiens
MLS-2384 Western Blot Influence on protein activity 2.50 µM A549 Homo sapiens
MLS-2384 MTT Influence on cell viability 1.00 µM DU145 Homo sapiens
MLS-2384 MTT Influence on cell viability 1.00 µM MDA-MB-468 Homo sapiens
MLS-2384 MTT Influence on cell viability 1.00 µM A2058 Homo sapiens
MLS-2384 MTT Influence on cell viability 1.00 µM A2780 Homo sapiens
MLS-2384 MTT Influence on cell viability 1.00 µM A549 Homo sapiens
MLS-2384 MTT Influence on cell viability 1.00 µM HepG2 Homo sapiens
MLS-2384 MTT Influence on cell viability 2.50 µM DU145 Homo sapiens
MLS-2384 MTT Influence on cell viability 2.50 µM MDA-MB-468 Homo sapiens
MLS-2384 MTT Influence on cell viability 2.50 µM A2058 Homo sapiens
MLS-2384 MTT Influence on cell viability 2.50 µM A2780 Homo sapiens
MLS-2384 MTT Influence on cell viability 2.50 µM A549 Homo sapiens
MLS-2384 MTT Influence on cell viability 2.50 µM HepG2 Homo sapiens
MLS-2384 MTT Influence on cell viability 5.00 µM DU145 Homo sapiens
MLS-2384 MTT Influence on cell viability 5.00 µM MDA-MB-468 Homo sapiens
MLS-2384 MTT Influence on cell viability 5.00 µM A2058 Homo sapiens
MLS-2384 MTT Influence on cell viability 5.00 µM A2780 Homo sapiens
MLS-2384 MTT Influence on cell viability 5.00 µM A549 Homo sapiens
MLS-2384 MTT Influence on cell viability 5.00 µM HepG2 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM DU145 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 1.00 µM A2058 Homo sapiens
MLS-2384 Western Blot Influence on cell apoptosis 2.50 µM A2058 Homo sapiens
MLS-2384 MTS Influence on cell viability 1.00 µM NHFD Homo sapiens
MLS-2384 MTS Influence on cell viability 2.50 µM NHFD Homo sapiens
MLS-2384 MTS Influence on cell viability 5.00 µM NHFD Homo sapiens
MLS-2384 MTS Influence on cell viability 10.00 µM NHFD Homo sapiens
MLS-2384 MTS Influence on cell viability 20.00 µM NHFD Homo sapiens
MLS-2384 Body weight Influence on tumor growth 25.00 mg/kg A2058 (xenograft) Mus musculus BALB/c
MLS-2384 Body weight Influence on tumor growth 50.00 mg/kg A2058 (xenograft) Mus musculus BALB/c
MLS-2384 Body weight Influence on tumor growth 100.00 mg/kg A2058 (xenograft) Mus musculus BALB/c
MLS-2384 Tumor volume Influence on tumor growth 25.00 mg/kg A2058 (xenograft) Mus musculus BALB/c