LLL-3

Name Value
Weight 0.000 N/A
Zinc ID N/A
Smiles N/A
Molecular formula N/A
Mode of inhibition Direct STAT SH2; Non-peptide small molecule; Structural analogue of STA-21
CAS N/A

Clinical Trials

Study title Status Conditions Link

References

Publication DOI Pubmed PMCID
Characterization of STAT3 activation and expression in canine and human osteosarcoma. BMC cancer Stacey L Fossey, Albert T Liao, Jennifer K McCleese, Misty D Bear, Jiayuh Lin, Pui-Kai Li, William C Kisseberth, Cheryl A London, 9, None, 2009-03-10, 2009-03-10, 10.1186/1471-2407-9-81 10.1186/1471-2407-9-81 19284568 PMC2666757

Filter data

Compound LLL-3
Experiment types CyQUANT cell proliferation assay kit, RT-PCR, SensoLyte® Homogeneous AMC Caspase-3/7 Assay, Western Blot, Zymography
Concentrations 1.00, 10.00, 40.00
Cell lines OSA16, OSA32, OSA8, SJSA, U2OS
Organisms Canis familriaris, Homo sapiens
Animal models
STAT proteins
Other Caspase 3, 7, Cleaved PARP, GAPDH, MMP2, PARP, Survivn, VEGF, β-actin

Experiments

Compound Experiment type Investigated event Concentration Cell line Organism Animal model Stat protein Details
LLL-3 CyQUANT cell proliferation assay kit Influence o cell proliferation 1.00 µM OSA8 Canis familriaris
LLL-3 CyQUANT cell proliferation assay kit Influence o cell proliferation 10.00 µM OSA8 Canis familriaris
LLL-3 CyQUANT cell proliferation assay kit Influence o cell proliferation 40.00 µM OSA8 Canis familriaris
LLL-3 CyQUANT cell proliferation assay kit Influence o cell proliferation 1.00 µM OSA16 Canis familriaris
LLL-3 CyQUANT cell proliferation assay kit Influence o cell proliferation 10.00 µM OSA16 Canis familriaris
LLL-3 CyQUANT cell proliferation assay kit Influence o cell proliferation 40.00 µM OSA16 Canis familriaris
LLL-3 CyQUANT cell proliferation assay kit Influence o cell proliferation 1.00 µM OSA32 Canis familriaris
LLL-3 CyQUANT cell proliferation assay kit Influence o cell proliferation 10.00 µM OSA32 Canis familriaris
LLL-3 CyQUANT cell proliferation assay kit Influence o cell proliferation 40.00 µM OSA32 Canis familriaris
LLL-3 CyQUANT cell proliferation assay kit Influence o cell proliferation 1.00 µM SJSA Homo sapiens
LLL-3 CyQUANT cell proliferation assay kit Influence o cell proliferation 10.00 µM SJSA Homo sapiens
LLL-3 CyQUANT cell proliferation assay kit Influence o cell proliferation 40.00 µM SJSA Homo sapiens
LLL-3 CyQUANT cell proliferation assay kit Influence o cell proliferation 1.00 µM U2OS Homo sapiens
LLL-3 CyQUANT cell proliferation assay kit Influence o cell proliferation 10.00 µM U2OS Homo sapiens
LLL-3 CyQUANT cell proliferation assay kit Influence o cell proliferation 40.00 µM U2OS Homo sapiens
LLL-3 SensoLyte® Homogeneous AMC Caspase-3/7 Assay Influence on cell apoptosis 10.00 µM OSA8 Canis familriaris
LLL-3 SensoLyte® Homogeneous AMC Caspase-3/7 Assay Influence on cell apoptosis 10.00 µM OSA16 Canis familriaris
LLL-3 SensoLyte® Homogeneous AMC Caspase-3/7 Assay Influence on cell apoptosis 10.00 µM OSA32 Canis familriaris
LLL-3 SensoLyte® Homogeneous AMC Caspase-3/7 Assay Influence on cell apoptosis 10.00 µM SJSA Homo sapiens
LLL-3 SensoLyte® Homogeneous AMC Caspase-3/7 Assay Influence on cell apoptosis 10.00 µM U2OS Homo sapiens
LLL-3 Western Blot Influence on protein activity 10.00 µM OSA8 Canis familriaris
LLL-3 Western Blot Influence on protein activity 40.00 µM OSA8 Canis familriaris
LLL-3 Western Blot Influence on protein activity 10.00 µM OSA16 Canis familriaris
LLL-3 Western Blot Influence on protein activity 40.00 µM OSA16 Canis familriaris
LLL-3 Western Blot Influence on protein activity 10.00 µM OSA32 Canis familriaris
LLL-3 Western Blot Influence on protein activity 40.00 µM OSA32 Canis familriaris
LLL-3 Western Blot Influence on protein activity 10.00 µM SJSA Homo sapiens
LLL-3 Western Blot Influence on protein activity 40.00 µM SJSA Homo sapiens
LLL-3 Western Blot Influence on protein activity 10.00 µM U2OS Homo sapiens
LLL-3 Western Blot Influence on protein activity 40.00 µM U2OS Homo sapiens
LLL-3 Western Blot Influence on protein activity 10.00 µM OSA8 Canis familriaris
LLL-3 Western Blot Influence on protein activity 40.00 µM OSA8 Canis familriaris
LLL-3 Western Blot Influence on protein activity 10.00 µM OSA16 Canis familriaris
LLL-3 Western Blot Influence on protein activity 40.00 µM OSA16 Canis familriaris
LLL-3 Western Blot Influence on protein activity 10.00 µM OSA32 Canis familriaris
LLL-3 Western Blot Influence on protein activity 40.00 µM OSA32 Canis familriaris
LLL-3 Western Blot Influence on protein activity 10.00 µM SJSA Homo sapiens
LLL-3 Western Blot Influence on protein activity 40.00 µM SJSA Homo sapiens
LLL-3 Western Blot Influence on protein activity 10.00 µM U2OS Homo sapiens
LLL-3 Western Blot Influence on protein activity 40.00 µM U2OS Homo sapiens
LLL-3 Western Blot Influence on protein activity 10.00 µM OSA8 Canis familriaris
LLL-3 Western Blot Influence on protein activity 40.00 µM OSA8 Canis familriaris
LLL-3 Western Blot Influence on protein activity 10.00 µM OSA16 Canis familriaris
LLL-3 Western Blot Influence on protein activity 40.00 µM OSA16 Canis familriaris
LLL-3 Western Blot Influence on protein activity 10.00 µM OSA32 Canis familriaris
LLL-3 Western Blot Influence on protein activity 40.00 µM OSA32 Canis familriaris
LLL-3 Western Blot Influence on protein activity 10.00 µM SJSA Homo sapiens
LLL-3 Western Blot Influence on protein activity 40.00 µM SJSA Homo sapiens
LLL-3 Western Blot Influence on protein activity 10.00 µM U2OS Homo sapiens
LLL-3 Western Blot Influence on protein activity 40.00 µM U2OS Homo sapiens
LLL-3 Western Blot Influence on protein activity 10.00 µM OSA8 Canis familriaris
LLL-3 Western Blot Influence on protein activity 40.00 µM OSA8 Canis familriaris
LLL-3 Western Blot Influence on protein activity 10.00 µM OSA16 Canis familriaris
LLL-3 Western Blot Influence on protein activity 40.00 µM OSA16 Canis familriaris
LLL-3 Western Blot Influence on protein activity 10.00 µM OSA32 Canis familriaris
LLL-3 Western Blot Influence on protein activity 40.00 µM OSA32 Canis familriaris
LLL-3 Western Blot Influence on protein activity 10.00 µM SJSA Homo sapiens
LLL-3 Western Blot Influence on protein activity 40.00 µM SJSA Homo sapiens
LLL-3 Western Blot Influence on protein activity 10.00 µM U2OS Homo sapiens
LLL-3 Western Blot Influence on protein activity 40.00 µM U2OS Homo sapiens
LLL-3 RT-PCR Influence on gene expression activity 40.00 µM OSA8 Canis familriaris
LLL-3 RT-PCR Influence on gene expression activity 40.00 µM OSA32 Canis familriaris
LLL-3 Zymography Influence on gene expression activity 10.00 µM OSA8 Canis familriaris
LLL-3 Zymography Influence on gene expression activity 40.00 µM OSA8 Canis familriaris
LLL-3 Zymography Influence on gene expression activity 10.00 µM OSA16 Canis familriaris
LLL-3 Zymography Influence on gene expression activity 40.00 µM OSA16 Canis familriaris
LLL-3 Zymography Influence on gene expression activity 10.00 µM OSA32 Canis familriaris
LLL-3 Zymography Influence on gene expression activity 40.00 µM OSA32 Canis familriaris
LLL-3 Zymography Influence on gene expression activity 10.00 µM SJSA Homo sapiens
LLL-3 Zymography Influence on gene expression activity 40.00 µM SJSA Homo sapiens
LLL-3 Zymography Influence on gene expression activity 10.00 µM U2OS Homo sapiens
LLL-3 Zymography Influence on gene expression activity 40.00 µM U2OS Homo sapiens
LLL-3 RT-PCR Influence on gene expression activity 40.00 µM OSA8 Canis familriaris
LLL-3 RT-PCR Influence on gene expression activity 40.00 µM U2OS Homo sapiens
LLL-3 RT-PCR Influence on gene expression activity 40.00 µM OSA8 Canis familriaris
LLL-3 RT-PCR Influence on gene expression activity 40.00 µM U2OS Homo sapiens
LLL-3 Western Blot Influence on protein activity 10.00 µM OSA8 Canis familriaris
LLL-3 Western Blot Influence on protein activity 40.00 µM OSA8 Canis familriaris
LLL-3 Western Blot Influence on protein activity 10.00 µM OSA16 Canis familriaris
LLL-3 Western Blot Influence on protein activity 40.00 µM OSA16 Canis familriaris
LLL-3 Western Blot Influence on protein activity 10.00 µM OSA32 Canis familriaris
LLL-3 Western Blot Influence on protein activity 40.00 µM OSA32 Canis familriaris
LLL-3 Western Blot Influence on protein activity 10.00 µM SJSA Homo sapiens
LLL-3 Western Blot Influence on protein activity 40.00 µM SJSA Homo sapiens
LLL-3 Western Blot Influence on protein activity 10.00 µM U2OS Homo sapiens
LLL-3 Western Blot Influence on protein activity 40.00 µM U2OS Homo sapiens