Ginkgolic Acid

Name Value
Weight 374.565 g/mol
Zinc ID ZINC42835776
Smiles CCCCCC/C=C\CCCCCCCCCc1cccc(O)c1C(=O)O
Molecular formula C24H38O3
Mode of inhibition N/A
CAS 111047-30-4

Clinical Trials

Study title Status Conditions Link

References

Publication DOI Pubmed PMCID
Ginkgolic Acid C 17:1, Derived from Ginkgo biloba Leaves, Suppresses Constitutive and Inducible STAT3 Activation through Induction of PTEN and SHP-1 Tyrosine Phosphatase. Molecules (Basel, Switzerland) Seung Ho Baek, Jong Hyun Lee, Chulwon Kim, Jeong-Hyeon Ko, Seung-Hee Ryu, Seok-Geun Lee, Woong Mo Yang, Jae-Young Um, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Gautam Sethi, Kwang Seok Ahn, 22, 2, 2017-02-13, 2017-02-13, 10.3390/molecules22020276 10.3390/molecules22020276 28208828 PMC6155672

Vendors

Company Lnk to product
MERCK/Sigma Aldrich https://www.sigmaaldrich.com/PL/pl/product/sial/75741?gclid=CjwKCAiA8bqOBhANEiwA-sIlN5SBue9LfoymW7aF1S86qfV8coh-n6YtEnHf0qTzpDneujvLpIQJHhoCyl4QAvD_BwE

Filter data

Compound Ginkgolic Acid
Experiment types Immunohistochemistry, Western Blot
Concentrations 10.00
Cell lines NeuN
Organisms Mus musculus
Animal models
STAT proteins STAT3, p-STAT3
Other ICAM, IL-1β, Lamin B, MMP9, MPO, NF-κB, TNF-α, iNOS2

Experiments

Compound Experiment type Investigated event Concentration Cell line Organism Animal model Stat protein Details
Ginkgolic Acid Immunohistochemistry Influence on neurons 10.00 mg/kg NeuN Mus musculus
Ginkgolic Acid Western Blot Influence on protein activity 10.00 mg/kg NeuN Mus musculus p-STAT3
Ginkgolic Acid Western Blot Influence on protein activity 10.00 mg/kg NeuN Mus musculus STAT3
Ginkgolic Acid Western Blot Influence on protein activity 10.00 mg/kg NeuN Mus musculus
Ginkgolic Acid Western Blot Influence on protein activity 10.00 mg/kg NeuN Mus musculus
Ginkgolic Acid Immunohistochemistry Influence on proinflammatory mediators expression 10.00 mg/kg NeuN Mus musculus
Ginkgolic Acid Immunohistochemistry Influence on proinflammatory mediators expression 10.00 mg/kg NeuN Mus musculus
Ginkgolic Acid Immunohistochemistry Influence on proinflammatory mediators expression 10.00 mg/kg NeuN Mus musculus
Ginkgolic Acid Immunohistochemistry Influence on proinflammatory mediators expression 10.00 mg/kg NeuN Mus musculus
Ginkgolic Acid Immunohistochemistry Influence on proinflammatory mediators expression 10.00 mg/kg NeuN Mus musculus
Ginkgolic Acid Immunohistochemistry Influence on proinflammatory mediators expression 10.00 mg/kg NeuN Mus musculus