Catechin

Name Value
Weight 290.271 g/mol
Zinc ID ZINC119978
Smiles Oc1cc(O)c2c(c1)O[C@@H](c1ccc(O)c(O)c1)[C@@H](O)C2
Molecular formula C15H14O6
Mode of inhibition N/A
CAS 154-23-4

Clinical Trials

Study title Status Conditions Link

References

Publication DOI Pubmed PMCID
Catechin Attenuates Coronary Heart Disease in a Rat Model by Inhibiting Inflammation. Cardiovascular toxicology Su Tu, Feng Xiao, Xiaoyan Min, Huiping Chen, Xiaochun Fan, Kejiang Cao, 18, 5, None, None, 10.1007/s12012-018-9449-z 10.1007/s12012-018-9449-z 29464499 29464499

Vendors

Company Lnk to product
TargetMol https://www.targetmol.com/compound/%28+%29-Catechin-Hydrate
AK Scientific Inc. https://aksci.com/item_detail.php?cat=1330AC
Ambinter http://www.ambinter.com/reference/Amb22169908
Ambinter http://www.ambinter.com/reference/Amb22467753
Ambinter http://www.ambinter.com/reference/Amb2747278
Ambinter http://www.ambinter.com/reference/Amb540975
Ambinter http://www.ambinter.com/reference/Amb6350547
AK Scientific Inc. https://aksci.com/item_detail.php?cat=J10967
AK Scientific Inc. https://aksci.com/item_detail.php?cat=Y0002
Molcore https://www.molcore.com/product/490-46-0
Mcule https://mcule.com/MCULE-4219942050/
TargetMol https://www.targetmol.com/compound/Catechin

Filter data

Compound Catechin
Experiment types ELISA, Metabolite concentration measurement, RT-qPCR, Western Blot
Concentrations 1.00, 10.00, 20.00, 30.00, 5.00
Cell lines
Organisms Rattus norvegicus
Animal models SPF Wistar
STAT proteins p-STAT3 (Tyr-705)
Other CRP, Creatine kinase, Creatine kinase-MB, FXR, IL-6, Lactate dehydrogenase, Lp-PLA2, NF-κB, TNF-α, cardiac troponin, p-Akt, β-actin

Experiments

Compound Experiment type Investigated event Concentration Cell line Organism Animal model Stat protein Details
Catechin ELISA Catechin role against coronary heart disease 1.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 5.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 10.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 20.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 30.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 1.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 5.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 10.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 20.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 30.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 1.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 5.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 10.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 20.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 30.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 1.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 5.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 10.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 20.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Catechin role against coronary heart disease 30.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Influence at the levels of ventricular ejection fraction (LVEF) and systolic internal diameter (LVIDs 1.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Influence at the levels of ventricular ejection fraction (LVEF) and systolic internal diameter (LVIDs 5.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Influence at the levels of ventricular ejection fraction (LVEF) and systolic internal diameter (LVIDs 10.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Influence at the levels of ventricular ejection fraction (LVEF) and systolic internal diameter (LVIDs 20.00 mg/kg Rattus norvegicus SPF Wistar
Catechin ELISA Influence at the levels of ventricular ejection fraction (LVEF) and systolic internal diameter (LVIDs 30.00 mg/kg Rattus norvegicus SPF Wistar
Catechin Metabolite concentration measurement Catechin role against coronary heart disease 5.00 mg/kg Rattus norvegicus SPF Wistar
Catechin Metabolite concentration measurement Catechin role against coronary heart disease 10.00 mg/kg Rattus norvegicus SPF Wistar
Catechin Metabolite concentration measurement Catechin role against coronary heart disease 20.00 mg/kg Rattus norvegicus SPF Wistar
Catechin RT-qPCR Anti-inflammatory function in coronary heart disease 5.00 mg/kg Rattus norvegicus SPF Wistar
Catechin RT-qPCR Anti-inflammatory function in coronary heart disease 10.00 mg/kg Rattus norvegicus SPF Wistar
Catechin RT-qPCR Anti-inflammatory function in coronary heart disease 20.00 mg/kg Rattus norvegicus SPF Wistar
Catechin RT-qPCR Anti-inflammatory function in coronary heart disease 5.00 mg/kg Rattus norvegicus SPF Wistar
Catechin RT-qPCR Anti-inflammatory function in coronary heart disease 10.00 mg/kg Rattus norvegicus SPF Wistar
Catechin RT-qPCR Anti-inflammatory function in coronary heart disease 20.00 mg/kg Rattus norvegicus SPF Wistar
Catechin RT-qPCR Anti-inflammatory function in coronary heart disease 5.00 mg/kg Rattus norvegicus SPF Wistar
Catechin RT-qPCR Anti-inflammatory function in coronary heart disease 10.00 mg/kg Rattus norvegicus SPF Wistar
Catechin RT-qPCR Anti-inflammatory function in coronary heart disease 20.00 mg/kg Rattus norvegicus SPF Wistar
Catechin RT-qPCR Anti-inflammatory function in coronary heart disease 5.00 mg/kg Rattus norvegicus SPF Wistar
Catechin RT-qPCR Anti-inflammatory function in coronary heart disease 10.00 mg/kg Rattus norvegicus SPF Wistar
Catechin RT-qPCR Anti-inflammatory function in coronary heart disease 20.00 mg/kg Rattus norvegicus SPF Wistar
Catechin Western Blot Influence on protein acticity 20.00 mg/kg Rattus norvegicus SPF Wistar p-STAT3 (Tyr-705)
Catechin Western Blot Influence on protein acticity 20.00 mg/kg Rattus norvegicus SPF Wistar
Catechin Western Blot Influence on protein acticity 20.00 mg/kg Rattus norvegicus SPF Wistar
Catechin Western Blot Influence on protein acticity 20.00 mg/kg Rattus norvegicus SPF Wistar
Catechin Western Blot Influence on protein acticity 20.00 mg/kg Rattus norvegicus SPF Wistar