BP-1-102/ 17o

Name Value
Weight 626.600 g/mol
Zinc ID ZINC72116229
Smiles CN(CC(=O)N(Cc1ccc(C2CCCCC2)cc1)c1ccc(C(=O)O)c(O)c1)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F
Molecular formula C29H27F5N2O6S
Mode of inhibition Direct STAT SH2; Non-peptide small molecule; Structural analogue of STA-21
CAS 1334493-07-0

Clinical Trials

Study title Status Conditions Link

Visualization

References

Publication DOI Pubmed PMCID
STAT3 inhibitor has potent antitumor activity in B-lineage acute lymphoblastic leukemia cells overexpressing the high mobility group A1 (HMGA1)-STAT3 pathway. Leukemia & lymphoma Amy Belton, Lingling Xian, Tait Huso, Michael Koo, Li Z Luo, James Turkson, Brent D G Page, Patrick T Gunning, Guosheng Liu, David L Huso, Linda M S Resar, 57, 11, None, 2016-03-08, 10.3109/10428194.2016.1153089 10.3109/10428194.2016.1153089 26952843 PMC5580963
Blocking interleukin-6 signaling inhibits cell viability/proliferation, glycolysis, and colony forming activity of human medulloblastoma cells. International journal of oncology Xiang Chen, Jia Wei, Chenglong Li, Christopher R Pierson, Jonathan L Finlay, Jiayuh Lin, 52, 2, None, 2017-11-22, 10.3892/ijo.2017.4211 10.3892/ijo.2017.4211 29207075 PMC5741369
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts. Proceedings of the National Academy of Sciences of the United States of America Xiaolei Zhang, Peibin Yue, Brent D G Page, Tianshu Li, Wei Zhao, Andrew T Namanja, David Paladino, Jihe Zhao, Yuan Chen, Patrick T Gunning, James Turkson, 109, 24, 2012-06-12, 2012-05-23, 10.1073/pnas.1121606109 10.1073/pnas.1121606109 22623533 PMC3386073

Vendors

Company Lnk to product
Selleckchem https://www.selleckchem.com/products/bp-1-102.html
MedChemExpress https://www.medchemexpress.com/BP-1-102.html
MERCK (Sigma Aldrich) https://www.sigmaaldrich.com/catalog/product/mm/573132m?lang=pl&region=PL
TargetMol https://www.targetmol.com/compound/BP-1-102
Caymanchemical https://www.caymanchem.com/product/28368/bp-1-102
BLDpharm https://www.bldpharm.com/products/1334493-07-0.html

Filter data

Compound BP-1-102/ 17o
Experiment types Annexin V/flow cytometry analysis , BioCoat invasion chamber assay, BrdU assay, CyQUANT cell proliferation assay, EMSA, Glycolisys assay, Individual tumor size , MTT Assay , Mean tumor size, Proliferaion Assay , RT-qPCR, Tumor size , Western Blot, Western Blot- Cyto , Western Blot- Nuc, Western Blot- WC, Wound healing assay
Concentrations 1.00, 10.00, 15.00, 2.50, 20.00, 3.00, 30.00, 5.00
Cell lines -/-MEFs, 231, 231/St3C, 3T3, A2058, A2058 (xenograft), A2780S, A549, Burktte, DAOY, DU145, Jurkat T-ALL, MDA-MB-231, MDA-MB-231 (xenograft), NIH3T3/ vSrc, Panc-1, REH tumor, REH-B-ALL, TE-71, UW288, v-Ras, v-Src, vSrc
Organisms Homo sapiens, Mus musculus
Animal models
STAT proteins STAT1:STAT3, STAT3, STAT3:STAT3, p-STAT3, p-STAT3 (Y705), pYSTAT3
Other AKT, Akt, Bcl-xL, CCND1, Cyclin D1, E-cadherin, EPSTI1, ERK, Erk1/2, FAK, GAPDH, HDAC1, HMGA1, IL-6, JAK1, JAK2, KLF8, Paxillin, RelA, SHC, SRC, Snail, Survivin, VEGF, c-Myc, p-AKT, p-AKT (S473), p-ERK1/2, p-JAK1, p-JAK2, p-RelA, p-Shc, pFAK, pPaxillin, pSRC, β-actin

Experiments

Compound Experiment type Investigated event Concentration Cell line Organism Animal model Stat protein Details
BP-1-102/ 17o Proliferaion Assay Influence on proliferation 5.00 µM REH-B-ALL Mus musculus
BP-1-102/ 17o Proliferaion Assay Influence on proliferation 5.00 µM Burktte Mus musculus
BP-1-102/ 17o Proliferaion Assay Influence on proliferation 5.00 µM Jurkat T-ALL Mus musculus
BP-1-102/ 17o Individual tumor size Influence on tumor growth 3.00 mg/kg REH tumor Mus musculus
BP-1-102/ 17o Mean tumor size Influence on tumor growth 3.00 mg/kg REH tumor Mus musculus
BP-1-102/ 17o Western Blot Influence on protein 5.00 µM REH-B-ALL Mus musculus p-STAT3
BP-1-102/ 17o Western Blot Influence on protein 5.00 µM REH-B-ALL Mus musculus STAT3
BP-1-102/ 17o RT-qPCR Influence on gene expression 5.00 µM REH-B-ALL Mus musculus
BP-1-102/ 17o RT-qPCR Influence on gene expression 5.00 µM REH-B-ALL Mus musculus
BP-1-102/ 17o RT-qPCR Influence on gene expression 5.00 µM REH-B-ALL Mus musculus
BP-1-102/ 17o RT-qPCR Influence on gene expression 2.50 µM REH-B-ALL Mus musculus
BP-1-102/ 17o RT-qPCR Influence on gene expression 2.50 µM REH-B-ALL Mus musculus
BP-1-102/ 17o RT-qPCR Influence on gene expression 2.50 µM REH-B-ALL Mus musculus
BP-1-102/ 17o MTT Assay Influence on cell viability 5.00 µM DAOY Homo sapiens
BP-1-102/ 17o MTT Assay Influence on cell viability 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o MTT Assay Influence on cell viability 5.00 µM UW288 Homo sapiens
BP-1-102/ 17o MTT Assay Influence on cell viability 10.00 µM UW288 Homo sapiens
BP-1-102/ 17o BrdU assay Influence on cell proliferation 5.00 µM DAOY Homo sapiens
BP-1-102/ 17o BrdU assay Influence on cell proliferation 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o BrdU assay Influence on cell proliferation 20.00 µM DAOY Homo sapiens
BP-1-102/ 17o BrdU assay Influence on cell proliferation 5.00 µM UW288 Homo sapiens
BP-1-102/ 17o BrdU assay Influence on cell proliferation 10.00 µM UW288 Homo sapiens
BP-1-102/ 17o BrdU assay Influence on cell proliferation 20.00 µM UW288 Homo sapiens
BP-1-102/ 17o Western Blot Influence on protein 10.00 µM DAOY Homo sapiens p-STAT3 (Y705)
BP-1-102/ 17o Western Blot Influence on protein 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o Western Blot Influence on protein 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o Western Blot Influence on protein 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o Western Blot Influence on protein 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o Western Blot Influence on protein 10.00 µM DAOY Homo sapiens STAT3
BP-1-102/ 17o Western Blot Influence on protein 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o Western Blot Influence on protein 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o Glycolisys assay Production of lactate 5.00 µM DAOY Homo sapiens
BP-1-102/ 17o Glycolisys assay Production of lactate 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o Glycolisys assay Production of lactate 20.00 µM DAOY Homo sapiens
BP-1-102/ 17o Glycolisys assay Production of lactate 5.00 µM UW288 Homo sapiens
BP-1-102/ 17o Glycolisys assay Production of lactate 10.00 µM UW288 Homo sapiens
BP-1-102/ 17o Glycolisys assay Production of lactate 20.00 µM UW288 Homo sapiens
BP-1-102/ 17o EMSA Influence on STAT3 activation 5.00 µM Homo sapiens STAT3:STAT3
BP-1-102/ 17o EMSA Influence on STAT3 activation 10.00 µM Homo sapiens STAT1:STAT3
BP-1-102/ 17o EMSA Influence on STAT3 activation 20.00 µM Homo sapiens STAT1:STAT3
BP-1-102/ 17o EMSA Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens STAT3:STAT3
BP-1-102/ 17o EMSA Influence on STAT3 activation 20.00 µM MDA-MB-231 Homo sapiens STAT3:STAT3
BP-1-102/ 17o EMSA Influence on STAT3 activation 10.00 µM DU145 Homo sapiens STAT3:STAT3
BP-1-102/ 17o EMSA Influence on STAT3 activation 20.00 µM DU145 Homo sapiens STAT3:STAT3
BP-1-102/ 17o EMSA Influence on STAT3 activation 10.00 µM NIH3T3/ vSrc Homo sapiens STAT3:STAT3
BP-1-102/ 17o EMSA Influence on STAT3 activation 20.00 µM NIH3T3/ vSrc Homo sapiens STAT3:STAT3
BP-1-102/ 17o EMSA Influence on STAT3 activation 10.00 µM Panc-1 Homo sapiens STAT3:STAT3
BP-1-102/ 17o EMSA Influence on STAT3 activation 20.00 µM Panc-1 Homo sapiens STAT3:STAT3
BP-1-102/ 17o EMSA Influence on STAT3 activation 10.00 µM A549 Homo sapiens STAT3:STAT3
BP-1-102/ 17o EMSA Influence on STAT3 activation 20.00 µM A549 Homo sapiens STAT3:STAT3
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens pYSTAT3
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens STAT3
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM MDA-MB-231 Homo sapiens pYSTAT3
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM MDA-MB-231 Homo sapiens STAT3
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM Panc-1 Homo sapiens pYSTAT3
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM Panc-1 Homo sapiens pYSTAT3
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM Panc-1 Homo sapiens STAT3
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM Panc-1 Homo sapiens STAT3
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM DU145 Homo sapiens pYSTAT3
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM DU145 Homo sapiens pYSTAT3
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM DU145 Homo sapiens STAT3
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM DU145 Homo sapiens STAT3
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 10.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 20.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Influence on STAT3 activation 15.00 µM DU145 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 10.00 µM TE-71 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 20.00 µM TE-71 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 30.00 µM TE-71 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 10.00 µM 3T3 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 20.00 µM 3T3 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 30.00 µM 3T3 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 10.00 µM A2780S Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 20.00 µM A2780S Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 30.00 µM A2780S Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 10.00 µM v-Ras Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 20.00 µM v-Ras Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 30.00 µM v-Ras Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 10.00 µM -/-MEFs Mus musculus
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 20.00 µM -/-MEFs Mus musculus
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 30.00 µM -/-MEFs Mus musculus
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 10.00 µM vSrc Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 20.00 µM vSrc Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 30.00 µM vSrc Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 10.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 20.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 30.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 10.00 µM DU145 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 20.00 µM DU145 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 30.00 µM DU145 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 10.00 µM A549 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 20.00 µM A549 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 30.00 µM A549 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 10.00 µM 231 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 20.00 µM 231 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 30.00 µM 231 Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 10.00 µM 231/St3C Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 20.00 µM 231/St3C Homo sapiens
BP-1-102/ 17o CyQUANT cell proliferation assay Influence on cell viability and proliferation 30.00 µM 231/St3C Homo sapiens
BP-1-102/ 17o Annexin V/flow cytometry analysis Influence on cell apoptosis 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Annexin V/flow cytometry analysis Influence on cell apoptosis 20.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Wound healing assay Influence on cell migration 10.00 µM v-Ras Homo sapiens
BP-1-102/ 17o Wound healing assay Influence on cell migration 15.00 µM v-Ras Homo sapiens
BP-1-102/ 17o Wound healing assay Influence on cell migration 10.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Wound healing assay Influence on cell migration 15.00 µM Panc-1 Homo sapiens
BP-1-102/ 17o Wound healing assay Influence on cell migration 10.00 µM 231 Homo sapiens
BP-1-102/ 17o Wound healing assay Influence on cell migration 15.00 µM 231 Homo sapiens
BP-1-102/ 17o Wound healing assay Influence on cell migration 10.00 µM v-Src Homo sapiens
BP-1-102/ 17o Wound healing assay Influence on cell migration 15.00 µM v-Src Homo sapiens
BP-1-102/ 17o Wound healing assay Influence on cell migration 10.00 µM DU145 Homo sapiens
BP-1-102/ 17o Wound healing assay Influence on cell migration 15.00 µM DU145 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 10.00 µM A2058 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 15.00 µM A2058 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 10.00 µM A2058 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 15.00 µM A2058 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 10.00 µM A2058 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 15.00 µM A2058 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 10.00 µM A2058 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 15.00 µM A2058 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors in cells transfected with control or Stat3 siRNA 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors in cells transfected with control or Stat3 siRNA 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot Supression of tumor supporting factors in cells transfected with control or Stat3 siRNA 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o BioCoat invasion chamber assay in cells overexpressing KLF8 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o BioCoat invasion chamber assay in cells overexpressing KLF8 5.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot- WC Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) 15.00 µM MDA-MB-231 Homo sapiens p-STAT3
BP-1-102/ 17o Western Blot- WC Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) 15.00 µM MDA-MB-231 Homo sapiens STAT3
BP-1-102/ 17o Western Blot- WC Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot- WC Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot- WC Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot- Cyto Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) 15.00 µM MDA-MB-231 Homo sapiens p-STAT3
BP-1-102/ 17o Western Blot- Cyto Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) 15.00 µM MDA-MB-231 Homo sapiens STAT3
BP-1-102/ 17o Western Blot- Cyto Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot- Cyto Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot- Cyto Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot- Nuc Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) 15.00 µM MDA-MB-231 Homo sapiens p-STAT3
BP-1-102/ 17o Western Blot- Nuc Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) 15.00 µM MDA-MB-231 Homo sapiens STAT3
BP-1-102/ 17o Western Blot- Nuc Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot- Nuc Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Western Blot- Nuc Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Tumor size Antitumor effect 1.00 mg/kg MDA-MB-231 (xenograft) Mus musculus
BP-1-102/ 17o Tumor size Antitumor effect 3.00 mg/kg MDA-MB-231 (xenograft) Mus musculus
BP-1-102/ 17o Tumor size Antitumor effect 3.00 mg/kg A2058 (xenograft) Mus musculus