BD750

Name Value
Weight 271.340 g/mol
Zinc ID ZINC9227018
Smiles C1CCC2=C(C1)C(=O)N(N2)C3=NC4=CC=CC=C4S3
Molecular formula C14H13N3OS
Mode of inhibition N/A
CAS 892686-59-8

Clinical Trials

Study title Status Conditions Link

References

Publication DOI Pubmed PMCID
Bacterial O-methylation of halogen-substituted phenols. Applied and environmental microbiology A S Allard, M Remberger, A H Neilson, 53, 4, None, None, 10.1111/j.1476-5381.2012.02172.x 10.1111/j.1476-5381.2012.02172.x 3579284 PMC3579284

Vendors

Company Lnk to product
Selleckchem https://www.selleckchem.com/products/bd750.html
MedChemExpress https://www.medchemexpress.com/bd750.html

Filter data

Compound BD750
Experiment types CCK-8, Flow cytometry , Flow cytometry- CFSE labelling , Flow cytometry- annexin V binding and propidium iodide staining, Western Blot
Concentrations 0.10, 0.62, 1.00, 1.25, 10.00, 12.50, 2.50, 20.00, 25.00, 3.13, 5.00, 50.00, 6.25
Cell lines CTLL-2, FLS, IL-4 activatedT-cells, Resting naive T cell, T-cells
Organisms Homo sapiens, Mus musculus
Animal models
STAT proteins STAT5, p-STAT5
Other Actin , Akt, CDK6, Cyclin D3, p-Akt, p-p70S6K, p70S6K

Experiments

Compound Experiment type Investigated event Concentration Cell line Organism Animal model Stat protein Details
BD750 Flow cytometry- CFSE labelling Influence on T cell proliferation 0.62 µM T-cells Homo sapiens
BD750 Flow cytometry- CFSE labelling Influence on T cell proliferation 1.25 µM T-cells Homo sapiens
BD750 Flow cytometry- CFSE labelling Influence on T cell proliferation 2.50 µM T-cells Homo sapiens
BD750 Flow cytometry- CFSE labelling Influence on T cell proliferation 5.00 µM T-cells Homo sapiens
BD750 CCK-8 Influence on cell viability 3.13 µM Resting naive T cell Homo sapiens
BD750 CCK-8 Influence on cell viability 6.25 µM Resting naive T cell Homo sapiens
BD750 CCK-8 Influence on cell viability 12.50 µM Resting naive T cell Homo sapiens
BD750 CCK-8 Influence on cell viability 25.00 µM Resting naive T cell Homo sapiens
BD750 CCK-8 Influence on cell viability 50.00 µM Resting naive T cell Homo sapiens
BD750 CCK-8 Influence on cell viability 3.13 µM IL-4 activatedT-cells Homo sapiens
BD750 CCK-8 Influence on cell viability 6.25 µM IL-4 activatedT-cells Homo sapiens
BD750 CCK-8 Influence on cell viability 12.50 µM IL-4 activatedT-cells Homo sapiens
BD750 CCK-8 Influence on cell viability 25.00 µM IL-4 activatedT-cells Homo sapiens
BD750 CCK-8 Influence on cell viability 50.00 µM IL-4 activatedT-cells Homo sapiens
BD750 CCK-8 Influence on cell viability 3.13 µM FLS Homo sapiens
BD750 CCK-8 Influence on cell viability 6.25 µM FLS Homo sapiens
BD750 CCK-8 Influence on cell viability 12.50 µM FLS Homo sapiens
BD750 CCK-8 Influence on cell viability 25.00 µM FLS Homo sapiens
BD750 CCK-8 Influence on cell viability 50.00 µM FLS Homo sapiens
BD750 Flow cytometry Influence on T cell proliferation 0.62 µM T-cells Mus musculus
BD750 Flow cytometry Influence on T cell proliferation 2.50 µM T-cells Mus musculus
BD750 Flow cytometry Influence on T cell proliferation 10.00 µM T-cells Mus musculus
BD750 Flow cytometry- annexin V binding and propidium iodide staining Influence on cell cycle 0.62 µM T-cells Mus musculus
BD750 Flow cytometry- annexin V binding and propidium iodide staining Influence on cell cycle 2.50 µM T-cells Mus musculus
BD750 Flow cytometry- annexin V binding and propidium iodide staining Influence on cell cycle 10.00 µM T-cells Mus musculus
BD750 Flow cytometry- annexin V binding and propidium iodide staining Influence on cell cycle 0.62 µM T-cells Homo sapiens
BD750 Flow cytometry- annexin V binding and propidium iodide staining Influence on cell cycle 2.50 µM T-cells Homo sapiens
BD750 Flow cytometry- annexin V binding and propidium iodide staining Influence on cell cycle 10.00 µM T-cells Homo sapiens
BD750 Western Blot Influence on cell cycle 0.62 µM T-cells Homo sapiens
BD750 Western Blot Influence on cell cycle 2.50 µM T-cells Homo sapiens
BD750 Western Blot Influence on cell cycle 10.00 µM T-cells Homo sapiens
BD750 Western Blot Influence on cell cycle 0.62 µM T-cells Homo sapiens
BD750 Western Blot Influence on cell cycle 2.50 µM T-cells Homo sapiens
BD750 Western Blot Influence on cell cycle 10.00 µM T-cells Homo sapiens
BD750 Western Blot Influence on cell cycle 0.62 µM T-cells Homo sapiens
BD750 Western Blot Influence on cell cycle 2.50 µM T-cells Homo sapiens
BD750 Western Blot Influence on cell cycle 10.00 µM T-cells Homo sapiens
BD750 Flow cytometry- CFSE labelling Infuence on cell proliferation in presence of IL-2 0.10 µM CTLL-2 Homo sapiens
BD750 Flow cytometry- CFSE labelling Infuence on cell proliferation in presence of IL-2 1.00 µM CTLL-2 Homo sapiens
BD750 Flow cytometry- CFSE labelling Infuence on cell proliferation in presence of IL-2 10.00 µM CTLL-2 Homo sapiens
BD750 Flow cytometry- CFSE labelling Infuence on cell proliferation in presence of IL-2 0.10 µM T-cells Homo sapiens
BD750 Flow cytometry- CFSE labelling Infuence on cell proliferation in presence of IL-2 1.00 µM T-cells Homo sapiens
BD750 Flow cytometry- CFSE labelling Infuence on cell proliferation in presence of IL-2 10.00 µM T-cells Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 1.00 µM CTLL-2 Homo sapiens p-STAT5
BD750 Western Blot Influence on protein activity in presence of IL-2 5.00 µM CTLL-2 Homo sapiens p-STAT5
BD750 Western Blot Influence on protein activity in presence of IL-2 20.00 µM CTLL-2 Homo sapiens p-STAT5
BD750 Western Blot Influence on protein activity in presence of IL-2 1.00 µM T-cells Homo sapiens p-STAT5
BD750 Western Blot Influence on protein activity in presence of IL-2 5.00 µM T-cells Homo sapiens p-STAT5
BD750 Western Blot Influence on protein activity in presence of IL-2 20.00 µM T-cells Homo sapiens p-STAT5
BD750 Western Blot Influence on protein activity in presence of IL-2 1.00 µM CTLL-2 Homo sapiens STAT5
BD750 Western Blot Influence on protein activity in presence of IL-2 5.00 µM CTLL-2 Homo sapiens STAT5
BD750 Western Blot Influence on protein activity in presence of IL-2 20.00 µM CTLL-2 Homo sapiens STAT5
BD750 Western Blot Influence on protein activity in presence of IL-2 1.00 µM T-cells Homo sapiens STAT5
BD750 Western Blot Influence on protein activity in presence of IL-2 5.00 µM T-cells Homo sapiens STAT5
BD750 Western Blot Influence on protein activity in presence of IL-2 20.00 µM T-cells Homo sapiens STAT5
BD750 Western Blot Influence on protein activity in presence of IL-2 1.00 µM CTLL-2 Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 5.00 µM CTLL-2 Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 20.00 µM CTLL-2 Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 1.00 µM T-cells Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 5.00 µM T-cells Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 20.00 µM T-cells Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 1.00 µM CTLL-2 Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 5.00 µM CTLL-2 Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 20.00 µM CTLL-2 Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 1.00 µM T-cells Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 5.00 µM T-cells Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 20.00 µM T-cells Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 1.00 µM CTLL-2 Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 5.00 µM CTLL-2 Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 20.00 µM CTLL-2 Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 1.00 µM T-cells Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 5.00 µM T-cells Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 20.00 µM T-cells Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 1.00 µM CTLL-2 Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 5.00 µM CTLL-2 Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 20.00 µM CTLL-2 Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 1.00 µM T-cells Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 5.00 µM T-cells Homo sapiens
BD750 Western Blot Influence on protein activity in presence of IL-2 20.00 µM T-cells Homo sapiens