| Study to Compare Feasibility of 1-step Injectable Artesunate vs. Conventional 2-step Injectable Artesunate |
Not yet recruiting |
Severe Malaria |
NCT05140278 |
| Evaluation of the Effect of Artesunate in Friedreich Ataxia (FA) |
Not yet recruiting |
Friedreich Ataxia |
NCT04921930 |
| Artesunate Ointment for the Treatment of High Grade Vulvar Intraepithelial Neoplasia (HSIL VIN2/3) |
Recruiting |
Vulvar Dysplasia|HPV-Related Vulvar Intraepithelial Neoplasia|Preinvasive Vulvar Disease|Vulva Intraepithelial Neoplasia|Vulvar Diseases |
NCT03792516 |
| Effectiveness and Safety of Artesunate-Amodiaquine and Artemether-Lumefantrine for the Treatment of Malaria in Yaounde |
Completed |
Malaria,Falciparum |
NCT04565184 |
| Very Severe Malaria Treated by Intravenous Artesunate |
Not yet recruiting |
Severe Malaria |
NCT04516317 |
| Assessment of Artesunate/Mefloquine in the Peruvian Amazon |
Completed |
Malaria, Falciparum |
NCT02084602 |
| Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3) |
Recruiting |
CIN 2/3|HPV Infection|Pre-Cancerous Dysplasia|Cervical Dysplasia|HPV Related Disease |
NCT04098744 |
| Efficacy and Safety of Artesunate + Amodiaquine With SLD of Primaquine for Treatment of Falciparum Malaria in Zanzibar |
Completed |
Plasmodium Falciparum Malaria |
NCT03773536 |
| The Safety and Efficacy of Pyronaridine-artesunate (Pyramax® or Artecom®)in COVID-19 Patients |
Recruiting |
Covid19 |
NCT04701606 |
| Efficacy and Safety of Artesunate-amodiaquine and Artemether-lumefantrine for the Treatment of Malaria in Cameroon |
Not yet recruiting |
Falciparum Malaria |
NCT04829695 |
| Evaluation of Artesunate-mefloquine as a Novel Alternative Treatment for Schistosomiasis in African Children |
Completed |
Schistosoma Haematobium|Schistosoma Mansoni |
NCT03893097 |
| Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/III Colorectal Cancer (NeoART-V) |
Recruiting |
Colorectal Cancer |
NCT03093129 |
| Intra-Anally Administered Artesunate in Patients With High-Grade Anal Intraepithelial Neoplasia (AIN 2/3) |
Completed |
HPV-Related Anal Intraepithelial Neoplasia|AIN2/3|Artesunate|Alternative Treatment|Anal Dysplasia|Precancerous Conditions|Human Papilloma Virus |
NCT03100045 |
| Dose-Escalation Study Evaluating the Safety and Pharmacokinetics of Artesunate in Patients With Hepatocellular Carcinoma |
Terminated |
Hepatocellular Carcinoma |
NCT02304289 |
| Phase I Study of Intravenous Artesunate for Solid Tumors |
Completed |
Solid Tumors |
NCT02353026 |
| Pharmacokinetic Study of Primaquine and Pyronaridine-Artesunate in Healthy Subjects |
Completed |
Healthy |
NCT01552330 |
| In Vivo Efficacy of Artemether-lumefantrine and Amodiaquine-artesunate in Mozambican Children (MEFI_III) |
Completed |
Malaria |
NCT04370977 |
| Pharmacokinetics and Pharmacodynamics of Intravenous Artesunate for Severe Malaria Treatment |
Unknown status |
Severe Malaria |
NCT01122134 |
| A Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/III Colorectal Cancer |
Active, not recruiting |
Colorectal Cancer|Bowel Cancer |
NCT02633098 |
| Efficacy and Safety of Artesunate Plus Standard of Care in Active Lupus Nephritis |
Recruiting |
Lupus Nephritis |
NCT03214731 |
| Intravenous Artesunate and Malaria |
Unknown status |
Malaria |
NCT01805232 |
| Tolerability and Efficacy of Artemether-Lumefantrine Versus Artesunate + Amodiaquine in Zanzibar |
Completed |
Plasmodium Falciparum Malaria |
NCT03764527 |
| The ASAP Study - Therapeutic Efficacy of Atovaquone-proguanil vs. Artesunate-atovaquone-proguanil in Cambodia |
Active, not recruiting |
Malaria |
NCT02297477 |
| Bio-availability of Rectal Artesunate in Children With Severe Falciparum Malaria |
Completed |
Malaria |
NCT02492178 |
| Safety and Efficacy of Pyronaridine Artesunate Versus Chloroquine in Children and Adult Patients With Acute Plasmodium Vivax Malaria |
Terminated |
Malaria |
NCT04368910 |
| Artemisinin Resistance In Malaria Treated With IV Artesunate |
Withdrawn |
Malaria |
NCT02640495 |
| Pharmacokinetics of Mefloquine-Artesunate in Pregnant Women With Uncomplicated Plasmodium Falciparum Infection |
Withdrawn |
Malaria|Pregnancy |
NCT01082718 |
| Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Uncomplicated Malaria in South Kivu, DR Congo |
Completed |
Malaria |
NCT02741024 |
| Phase II Dose-ranging Study of Pyronaridine/Artesunate in Adults Patients With Plasmodium Falciparum Malaria |
Completed |
Plasmodium Falciparum Malaria |
NCT01594931 |
| Efficacy of Artesunate + Amodiaquine Versus Artemether-lumefantrine for Falciparum Malaria in Zanzibar, 2005 |
Completed |
Plasmodium Falciparum Malaria |
NCT03768908 |
| Clinical Investigation of In-vivo Susceptibility of P.Falciparum to Artesunate in Western Cambodia |
Completed |
Falciparum Malaria |
NCT00493363 |
| Safety and Efficacy of Artesunate & Curcumin in Crohn's Disease |
Not yet recruiting |
Crohn's Disease |
NCT04713631 |
| Parenteral Artesunate Compared to Quinine as a Cause of Late Anaemia in African Children With Malaria |
Completed |
Anaemia |
NCT02092766 |
| Effectiveness of the Association Artesunate and Mefloquine in the Treatment of Malaria by Plasmodium Falciparum |
Completed |
Falciparum Malaria |
NCT01144702 |
| Relative Bioavailability of Pyronaridine-artesunate in Tablet and Granule Formulations, in Healthy Volunteers |
Completed |
Malaria |
NCT01868438 |
| Artesunate Plus Amodiaquine in Malaria in Cote d'Ivoire |
Completed |
Malaria |
NCT01023399 |
| Efficacy and Safety of Pyronaridine-artesunate for the Treatment in Uncomplicated Falciparum Malaria |
Completed |
Malaria, Falciparum |
NCT02389439 |
| In Vivo Efficacy of Artemether-Lumefantrine and Artesunate-Amodiaquine for Uncomplicated P. Falciparum Malaria |
Completed |
MALARIA, FALCIPARUM |
NCT02637128 |
| Efficacy of Artesunate-amodiaquine (AS-AQ) in Children With Malaria and Severe Acute Malnutrition, Madaoua, Niger 2010 |
Withdrawn |
Malaria, Falciparum|Malnutrition|Child |
NCT01204411 |
| Safety and Efficacy Study of IV Artesunate to Treat Malaria |
Completed |
Malaria |
NCT00298610 |
| Evaluating the Efficacy of Artesunate in Adults With Mild Symptoms of COVID-19 |
Not yet recruiting |
Covid 19 Positive|Corona Virus Infection |
NCT04387240 |
| Bioequivalence Study Comparing Artesunate Tablet To Arsuamoon® Tablets (Guilin-China) In Healthy Subjects |
Completed |
Falciparum Malaria |
NCT00894374 |
| A Study Comparing Blood Levels After Single-Dose Administration Of Artesunate Sachets (Pfizer) Versus Single-Dose Administration Of Arsuamoon® Tablets (Guilin-China) In Healthy Subjects |
Completed |
Healthy Volunteers |
NCT00875030 |
| Intravaginal Artesunate for the Treatment of HPV+ High Grade Cervical Intraepithelial Neoplasia (CIN2/3) |
Completed |
Cervical Intraepithelial Neoplasia Grade 2/3|High-risk HPV (Any Strain) |
NCT02354534 |
| Study of the Safety of Intravenous Artesunate |
Completed |
Malaria|Malaria, Cerebral |
NCT00292942 |
| Study of Pharmacokinetics and Pharmacodynamics of Artesunate in Pregnant Women in the Democratic Republic of Congo |
Completed |
Malaria |
NCT00538382 |
| Study of Artesunate in Metastatic Breast Cancer |
Completed |
Metastatic Breast Cancer|Locally Advanced Breast Cancer |
NCT00764036 |
| Phase II Artesunate Study in Severe Malaria |
Completed |
Malaria |
NCT00522132 |
| Efficacy and Safety of Artesunate-amodiaquine-methylene for Malaria Treatment in Children |
Completed |
Uncomplicated Falciparum Malaria |
NCT01407887 |
| Pharmacokinetic of Mefloquine-Artesunate in Plasmodium Falciparum Malaria Infection in Pregnancy |
Completed |
Plasmodium Falciparum Malaria |
NCT00701961 |
| Harmonized AS/MQ Efficacy Study - Thailand |
Completed |
Malaria |
NCT02052323 |
| Pyronaridine-artesunate and Artemether-lumefantrine for the Treatment of Paediatric Malaria |
Completed |
Malaria |
NCT02411994 |
| Tracking Resistance to Artemisinin (TRAC) |
Completed |
Falciparum Malaria |
NCT01350856 |
| Pyronaridine - Artesunate (3:1) Versus Mefloquine Plus Artesunate in Plasmodium Falciparum Malaria Patients |
Completed |
Falciparum Malaria |
NCT00403260 |
| Pyronaridine-artesunate With Low Dose Primaquine for Preventing P. Falciparum Transmission |
Completed |
Malaria,Falciparum |
NCT04049916 |
| Artesunate Plus Sulfadoxine-pyrimethamine Pharmacokinetics, Efficacy, Gametocytes Carriage and Birth Outcomes in Pregnant Women With Malaria |
Terminated |
Malaria |
NCT00331708 |
| Pyronaridine/Artesunate -Ritonavir Drug Drug Interaction Study |
Completed |
Malaria |
NCT01156389 |
| P. Knowlesi Trial of Artesunate-mefloquine Versus Chloroquine |
Completed |
Uncomplicated Plasmodium Knowlesi Malaria |
NCT01708876 |
| In Vivo Efficacy of Artemether-lumefantrine and Amodiaquine-artesunate in Mozambican Children |
Completed |
Malaria |
NCT02168569 |
| Dose Ranging Study of Ferroquine With Artesunate in African Adults and Children With Uncomplicated Plasmodium Falciparum Malaria |
Terminated |
Plasmodium Falciparum Infection |
NCT00988507 |
| Amodiaquine-Artesunate & Artemether-Lumefantrine Efficacy in Burkina Faso |
Completed |
Malaria |
NCT01697787 |
| Drug Interaction Study of Pyronaridine-artesunate and Metoprolol and Pyronaridine-artesunate Re-dosing Study in Healthy Volunteers |
Completed |
Malaria |
NCT01523002 |
| Bioequivalence of Pyronaridine Artesunate To-be-marketed Tablet to the Clinical Trial Reference Tablet |
Completed |
Malaria |
NCT00682630 |
| Artesunate in Preemptive Treatment of Human Cytomegalovirus (CMV) in Stem Cell Transplant Recipients |
Completed |
Cytomegalovirus Infections |
NCT00284687 |
| Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria |
Completed |
Malaria |
NCT00440999 |
| Effectiveness and Safety of Intermittent Preventive Treatment for Malaria Using Either Dihydroartemisinin-piperaquine or Artesunate-amodiaquine in Reducing Malaria Related Morbidities and Improving Cognitive Ability in School-aged Children in Tanzania |
Active, not recruiting |
Malaria,Falciparum|Anemia |
NCT03640403 |
| Safety and Efficacy Study of Artesunate and Mefloquin in Children With Uncomplicated Malaria |
Completed |
Malaria |
NCT00978172 |
| SPK Study in Afghanistan |
Completed |
Uncomplicated P. Falciparum Malaria |
NCT01707199 |
| Chlorproguanil-Dapsone-Artesunate (CDA) Versus Chlorproguanil-Dapsone (LAPDAP) For Uncomplicated Malaria |
Completed |
Malaria, Falciparum |
NCT00371735 |
| A Trial of the Efficacy of Artesunate and Three Quinine Regimens in the Treatment of Severe Malaria in Children at the Ebolowa Regional Hospital - Cameroon |
Completed |
Malaria |
NCT02563704 |
| Study of the Safety of Intravenous Artesunate |
Completed |
Malaria|Malaria, Cerebral |
NCT00292929 |
| Efficacy and Tolerability of Artesunate Amodiaquine Versus Chloroquine in the Treatment of Uncomplicated Plasmodium Vivax Malaria |
Completed |
Malaria |
NCT01378286 |
| Efficacy and Safety of Amodiaquine and Amodiaquine-Artesunate |
Unknown status |
Malaria |
NCT00238017 |
| Safety and Efficacy Dose of Artesunate Used in Combination With LAPDAP Treatment of Uncomplicated Falciparum Malaria |
Completed |
Malaria |
NCT00519467 |
| Efficacy of Artesunate-Mefloquine Combination Therapy in Trat Province, Thailand |
Completed |
Plasmodium Falciparum Malaria |
NCT01659281 |
| Pyronaridine Artesunate 3:1 Granule Formulation vs. Coartem© Crushed Tablets in P. Falciparum Malaria Pediatric Patients |
Completed |
Malaria |
NCT00541385 |
| Phase II Dose Ranging Study of Artesunate |
Completed |
Falciparum Malaria|Uncomplicated Malaria |
NCT00459615 |
| Chlorproguanil-Dapsone-Artesunate Versus COARTEM For Uncomplicated Malaria |
Completed |
Malaria, Falciparum |
NCT00344006 |
| Pyronaridine and Artesunate (3:1) in Children With Acute Uncomplicated Plasmodium Falciparum Malaria |
Completed |
Uncomplicated Plasmodium Falciparum Malaria |
NCT00331136 |
| Azithromycin + Artesunate v Artemether-lumefantrine in Uncomplicated Malaria. |
Completed |
Malaria |
NCT00694694 |
| Artemether-lumefantrine (AL) Versus Artesunate + Amodiaquine (ASAQ) for the Treatment of Uncomplicated Falciparum Malaria in Burkina Faso |
Completed |
Uncomplicated P. Falciparum Malaria in Children |
NCT01017770 |
| Efficacy of Artemisinin Combination Therapies for the Treatment of Uncomplicated P. Falciparum in Pregnancy in Brazil |
Terminated |
Malaria |
NCT01082731 |
| Artesunate+Sulfadoxine-Pyrimethamine for the Treatment of Uncomplicated Falciparum Malaria |
Completed |
Falciparum Malaria |
NCT01115439 |
| Study of Malaria Treatment at Phuoc Long Hospital, Binh Phuoc Province, Vietnam |
Completed |
Malaria |
NCT01165372 |
| A Randomised Trial of Artesunate-sulfamethoxypyrazine/Pyrimethamine Versus Praziquantel for the Treatment of S. Mansoni |
Completed |
Schistosoma Mansoni |
NCT01054651 |
| Amodiaquine+Artesunate for Uncomplicated Malaria Treatment |
Completed |
Uncomplicated Malaria |
NCT01213433 |
| Pyronaridine Artesunate (3:1) Versus Coartem® in P Falciparum Malaria Patients |
Completed |
Malaria |
NCT00422084 |
| Malaria Treatment With Injectable ArteSunate |
Completed |
Severe Malaria |
NCT01828333 |
| Efficacy, Effect on Gametocytes and Tolerability of the Addition of Artesunate to Amodiaquine in Colombia |
Completed |
Malaria,Falciparum|Malaria|Antimalarials |
NCT00378625 |
| Efficacy of Artemether-lumefantrine, Artesunate-amodiaquine and Dihydroartemisinin-piperaquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in Malawi |
Completed |
Malaria, Falciparum |
NCT01326754 |
| ACT for the Home Management in Malagasy Children |
Completed |
Fever|Suspected Malaria |
NCT00612547 |
| Bioavailability of the Fixed Combination of Amodiaquine and Artesunate Under Fed & Fasted Conditions |
Completed |
Malaria |
NCT00386503 |
| Efficacy and Safety of Artemisinin-based Combination Treatments in the Democratic Republic of the Congo |
Completed |
Malaria |
NCT02940756 |
| Assessment of the Therapeutic Efficacy and Tolerability of the Artesunate/Amodiaquina Combination and Artemether/Lumefantrine Combination, Treatment of Uncomplicated P. Falciparum Malaria in the Department of ChocĂł (Colombia) |
Completed |
P. Falciparum Malaria |
NCT04877626 |
| Efficacy Study of Amodiaquine-Artesunate and Artemether-Lumefantrine for the Treatment of Uncomplicated Malaria |
Completed |
Malaria, Falciparum |
NCT01567423 |
| A Randomised Trial of Artekin and Artesunate & Amodiaquine for Uncomplicated Malaria in Timika, Papua, Indonesia. |
Completed |
Malaria, Falciparum|Malaria, Vivax |
NCT00157885 |
| Compare the Effectiveness Between Existing Treatment and New Treatment |
Completed |
P. Falciparum Malaria |
NCT01640587 |
| ATAQ EASY: Artesunate + Amodiaquine Fixed Dose Combination in the Treatment of Uncomplicated Plasmodium Falciparum Malaria |
Completed |
Malaria |
NCT00316329 |
| Safety and Efficacy of Recommended Antimalarial in the Democratic Republic of the Congo |
Recruiting |
Malaria |
NCT04618523 |
| Amodiaquine Plus Artesunate Versus Lapdap Plus Artesunate in the Treatment of Uncomplicated P. Falciparum Malaria in Malawi |
Completed |
Malaria, Falciparum |
NCT00164359 |
| Artesunate Plus Sulfadoxine-Pyrimethamine Versus Chloroquine for Vivax Malaria |
Completed |
Malaria, Vivax |
NCT00486694 |
| P. Falciparum Resistance to Artemisinin in Vietnam |
Unknown status |
Drug Resistant Malaria Due to Plasmodium Falciparum |
NCT02604966 |
| Efficacy of Artesunate + Amodiaquine Four Years After Its Introduction in Zanzibar |
Suspended |
Malaria |
NCT00465257 |
| Efficacy and Safety of ASAQ and PD for the Treatment of Uncomplicated Falciparum Malaria in Mainland Tanzania |
Completed |
Uncomplicated Falciparum Malaria |
NCT03431714 |
| Safety and Efficacy of Methylene Blue Combined With Amodiaquine or Artesunate for Malaria Treatment in Children of Burkina Faso |
Completed |
Malaria |
NCT00545935 |
| In Vivo and in Vitro Efficacy of Antimalarial Treatments in Children in Burkina Faso |
Completed |
Malaria |
NCT00808951 |
| Cohort Study in Senegal Comparing Artesunate + Amiodaquine in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks |
Completed |
Malaria |
NCT00540410 |
| Artemisone for the Treatment of Uncomplicated Falciparum Malaria in Western Cambodia |
Withdrawn |
Uncomplicated Falciparum Malaria |
NCT00936767 |
| Trial of Artesunate Combination Therapy in Pakistan |
Completed |
Uncomplicated Falciparum Malaria |
NCT00959517 |
| Artemisinin Resistance in Cambodia II |
Completed |
Falciparum Malaria |
NCT00722150 |
| Comparing Praziquantel Versus Artesunate + Sulfamethoxypyrazine/Pyrimethamine for Treating Schistosomiasis |
Completed |
Schistosoma Haematobium |
NCT00510159 |
| Azithromycin Combination Therapy for the Treatment of Uncomplicated Falciparum Malaria in Bangladesh |
Completed |
Uncomplicated Falciparum Malaria |
NCT00356005 |
| Study on the Treatment of Vivax Malaria |
Completed |
Vivax Malaria |
NCT01074905 |
| Community Access to Rectal Artesunate for Malaria |
Active, not recruiting |
Malaria |
NCT03568344 |
| A Comparative Safety and Activity Study With Ferroquine Associated With Artesunate Versus Amodiaquine Associated With Artesunate in African Adult Patients With Uncomplicated Malaria |
Completed |
Malaria |
NCT00563914 |
| Evaluation of Oral Activated Charcoal on Antimalarial Drug's Ability to Kill Parasites in Malian Children With Malaria |
Completed |
Malaria|Severe Malaria |
NCT01955382 |
| Efficacy and Safety of Azithromycin and Artesunate in Pregnant Women |
Completed |
Malaria |
NCT00287300 |
| Randomised Trial of 3 Artemisinin Combination Therapy for Malaria in Pregnancy |
Active, not recruiting |
Malaria |
NCT01054248 |
| Tolerability and Efficacy of CD+A Compared to AQ+SP for the Treatment of P.Falciparum Malaria in Rwandan Children |
Completed |
Malaria |
NCT00461578 |
| Efficacy and Effectiveness of Combined Therapy for Uncomplicated Malaria Treatment in Peru |
Completed |
Malaria Falciparum |
NCT00164216 |
| Artemisinin-Based Combination Therapy: Clinical Trials in Cameroon |
Completed |
Malaria |
NCT00297882 |
| Fosmidomycin With Clindamycin or With Clindamycin Plus Artesunate |
Withdrawn |
Malaria |
NCT01002183 |
| Efficacy of Artemisinin Combination Therapies for the Treatment of Uncomplicated P. Vivax in Pregnancy in Brazil (PAACT-PV) |
Terminated |
Plasmodium Vivax Malaria |
NCT01107145 |
| Compliance to Artesunate-Amodiaquine Therapy for Uncomplicated Malaria in Rural Ghana |
Completed |
Malaria |
NCT00873938 |
| Treatment Efficacy and Malaria TRANSmission After Artemisinin Combination Therapy 2 (TRANSACT2) |
Completed |
Malaria |
NCT01939886 |
| Pyramax in Asymptomatic Carriers of P. Falciparum Monoinfections |
Unknown status |
Malaria,Falciparum |
NCT03814616 |
| Plasmodium Falciparum Clearance Rates in Response to Artesunate in Eastern Cambodia |
Completed |
Malaria |
NCT01240603 |
| To Evaluate Efficacy, Safety, Tolerability and PK of Intravenous Cipargamin in Participants With Severe Plasmodium Falciparum Malaria |
Not yet recruiting |
Severe Malaria |
NCT04675931 |
| Efficacy,Safety and Tolerability of Dihydroartemisinin-Piperaquine for Uncomplicated Malaria in Pregnancy in Ghana |
Completed |
Pregnancy Complicated by Malaria as Antepartum Condition |
NCT01231113 |
| Have Malaria Infections in Kenya Become Less Responsive to Artemisinin Treatment? |
Unknown status |
Malaria |
NCT01190371 |
| Amodiaquine+Artesunate vs. Artemether-Lumefantrine for Uncomplicated Malaria in Ghanaian Children |
Unknown status |
Uncomplicated Malaria |
NCT00406146 |
| ACT With Chloroquine, Amodiaquine & Sulphadoxine-pyrimethamine in Pakistan |
Completed |
Malaria|Falciparum Malaria|Vivax Malaria |
NCT00158548 |
| Efficacy of Amodiaquine-artesunate in Children Aged 6-59 Months With Uncomplicated P. Falciparum Malaria |
Completed |
Malaria |
NCT00425763 |
| Cohort Event Monitoring in Sub Saharan Africa |
Completed |
Malaria |
NCT02817919 |
| Safety and Efficacy of Methylene Blue Combined With Artesunate or Amodiaquine for Malaria Treatment in Children of Burkina Faso: a Pilot Study |
Completed |
Malaria |
NCT00354380 |
| Randomized Trial on Effectiveness of ACTs in Ghana |
Terminated |
Malaria, Falciparum |
NCT00374205 |
| Efficacy and Safety of Dihydroartemisinin/Piperaquine (Artekin®) for the Treatment of Uncomplicated Malaria in Peru |
Completed |
Malaria |
NCT00373607 |
| A Trial of Intermittent Treatment in the Prevention of Malaria in Senegalese Children |
Completed |
Malaria |
NCT00132561 |
| Randomized Trial of Two Antimalarial Treatments for Clearing Low Density P.Falciparum Parasitaemia in Sudan |
Completed |
Plasmodium Infections |
NCT00330902 |
| Chloroquine Alone or in Combination for Malaria in Children in Malawi |
Completed |
Plasmodium Falciparum Infection |
NCT00379821 |
| A Randomised Efficacy Study of Combination Antimalarials to Treat Uncomplicated Malaria |
Completed |
Malaria |
NCT00203814 |
| Azithromycin Combination Therapy for the Treatment of Severe Malaria |
Completed |
Falciparum Malaria |
NCT01374126 |
| Efficacy of Three ACTs for the Treatment of Falciparum Malaria in Maradi Niger |
Completed |
Malaria |
NCT01755559 |
| Rigorous Assessment of P. Vivax Relapses and Primaquine Efficacy for Radical Cure |
Recruiting |
Vivax Malaria |
NCT04706130 |
| Kintampo Trial of Combination Therapy for Malaria |
Completed |
Malaria |
NCT00119145 |
| Effectiveness of Intermittent Preventive Treatment for Malaria in Children |
Completed |
Malaria |
NCT00119132 |
| Intermittent Preventive Treatment for Malaria in Patient With Sickle Cell Disease |
Completed |
Malaria|Sickle Cell Crisis |
NCT01319448 |
| Cohort Event Monitoring Study of Pyramax® |
Completed |
Malaria,Falciparum |
NCT03201770 |
| Efficacy of Combination Therapy for Prevention of Effects of Malaria During Pregnancy |
Completed |
Malaria |
NCT00164255 |
| Cohort Study in Uganda Comparing Artesunate + Amiodaquine (Coarsucam) Versus Artemether + Lumenfantrine (Coartem) in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks |
Completed |
Malaria |
NCT00699920 |
| Treatment of Uncomplicated Malaria in Benin |
Completed |
Uncomplicated Malaria |
NCT00460369 |
| Malaria as a Risk Factor for COVID-19 in Western Kenya and Burkina Faso |
Recruiting |
Covid-19|Malaria |
NCT04695197 |
| Drug Combinations of Atovaquone-Proguanil (AP) With ACT |
Recruiting |
Plasmodium Falciparum Malaria (Drug Resistant) |
NCT03726593 |
| Arsucam® (Artesunate + Amiodaquine) Efficacy and TOLerance |
Completed |
Malaria |
NCT00445796 |
| Pharmacokinetics, Efficacy, Gametocyte Carriage, Birth Outcomes Following Sulfadoxine-pyrimethamine Intermittent Presumptive Treatment in Pregnant Women |
Completed |
Malaria |
NCT00380146 |
| Adherence to Antimalarial Drugs in Sierra Leone |
Completed |
Malaria |
NCT01967472 |
| Dolutegravir Interactions With Artemisinin-based Combination Therapies |
Completed |
Malaria|HIV |
NCT02242799 |
| Evaluation of Potential Effect of Artemether - Lumefantrine and Malaria Drugs on Auditory Function |
Completed |
Malaria|Falciparum |
NCT00444106 |
| Efficacy, Safety and Pharmacokinetic of ArtequinTM P. Falciparum Malaria |
Completed |
Malaria |
NCT00243737 |
| Artemisinin-Based Antimalarial Combinations and Clinical Response in Cameroon |
Completed |
Malaria |
NCT01845701 |
| Methylene Blue Against Falciparum Malaria in Burkina Faso |
Completed |
Malaria, Falciparum |
NCT02851108 |
| Evaluating the Efficacy of Artesunate-mefloquine and the Relative Roles of Resistance Genetic Markers |
Completed |
P. Falciparum Malaria|P. Falciparum Malaria Mixed Infection |
NCT02427360 |
| Study of ACTs Plus Primaquine for Uncomplicated Plasmodium Vivax Malaria |
Completed |
Vivax Malaria |
NCT01288820 |
| Artemisinin Resistance in Bangladesh |
Completed |
Malaria |
NCT00639873 |
| Efficacy, Safety, and Tolerability of Dihydroartemisinin-piperaquine + Mefloquine Compared to Dihydroartemisinin-piperaquine or Artesunate-mefloquine in Patients With Uncomplicated Falciparum Malaria in Cambodia |
Completed |
Acute Falciparum Malaria |
NCT02612545 |
| Efficacy of Sulphadoxine-pyrimethamine and Artemisinin-containing Combination Therapy for Malaria |
Completed |
Malaria (Uncomplicated) |
NCT00140361 |
| A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combinations of 2 Anti-malarial Drugs (Asia) |
Recruiting |
Plasmodium Falciparum Malaria (Uncomplicated) |
NCT03939104 |
| Impact of Artemisinin-based Combination Therapy and Quinine on Treatment Failure and Resistance in Uncomplicated Malaria |
Completed |
Malaria |
NCT01374581 |
| Comparison of ISTp- PYRAMAX-US-RDT to IPTp-SP to Prevent Malaria in Pregnant Women in DRC (ULTRAPYRAPREG) |
Recruiting |
Malaria in Pregnancy |
NCT04783051 |
| A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combina-tions of 2 Anti-malarial Drugs. |
Recruiting |
Plasmodium Falciparum Malaria (Uncomplicated) |
NCT03923725 |
| Safe and Efficacious Artemisinin-based Combination Treatments for African Pregnant Women With Malaria |
Completed |
Malaria in Pregnancy |
NCT00852423 |
| Comparison of Two Antimalarial Drugs Regimens in Patient With Plasmodium Vivax Malaria in Thailand |
Unknown status |
Acute Uncomplicated Malaria With P.Vivax Infection |
NCT01662700 |
| Intermittent Preventive Treatment (IPTi) for the Prevention of Malaria and Anaemia in PNG Infants |
Completed |
Malaria|Anemia |
NCT00285662 |
| Assessing the Efficacy of Four Drug Combinations as the Next First-line Therapy for Uncomplicated Malaria in Malawi |
Completed |
Malaria, Falciparum |
NCT00164710 |
| The Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients |
Completed |
COVID-19 |
NCT04475107 |
| Age of Exposure and Immunity to Malaria in Infants |
Completed |
Malaria |
NCT00231452 |
| Evaluation of Three Artemisinin-based Combinations for the Treatment of Uncomplicated Malaria in Childreen in Burkina Faso (CHIMIO2) |
Not yet recruiting |
Malaria|Burkina Faso |
NCT04778813 |
| In Vivo and In Vitro Efficacy of Artemisinin Combination Therapy |
Completed |
Malaria |
NCT01976780 |
| Multi-Centre Trial Comparing Three Artemisinin-Based Combination Treatments on P. Falciparum Malaria |
Completed |
Plasmodium Falciparum Malaria |
NCT00484900 |
| A Randomised Efficacy Study of Combination Antimalarials to Treat Uncomplicated Malaria |
Completed |
Malaria |
NCT00203736 |
| Evaluation of 4 Artemisinin-based Combinations for Treating Uncomplicated Malaria in African Children |
Completed |
Fever|Malaria |
NCT00393679 |
| Artemisinin Resistance in Cambodia |
Completed |
Malaria, Falciparum |
NCT00479206 |
| Trial of the Effectiveness of AQ/AS, SP/AQ and SP/CQ for Uncomplicated Malaria in Gambian Children |
Completed |
Malaria |
NCT00118807 |
| Pharmacokinetic Interactions Between Antiretroviral Agents and Antimalarial Drug Combinations |
Completed |
HIV Infections|Malaria |
NCT00697892 |
| ACT MALI: Treatment of Malaria Based on Combination Therapies |
Completed |
Malaria |
NCT00452907 |
| Molecular Surveillance of Artemisinin Resistance Malaria in Myanmar |
Completed |
Drug Resistance|Plasmodium Falciparum Malaria |
NCT02792816 |
| Paracetamol Effect on Oxidative Stress and Renal Function in Severe Malaria |
Completed |
Malaria |
NCT01641289 |
| Effect of Antimalarial Treatment on Gametocyte Carriage in Asymptomatic P. Falciparum |
Completed |
Asymptomatic P.Falciparum Malaria |
NCT00289250 |
| Combination Antimalarials in Uncomplicated Malaria |
Completed |
Malaria |
NCT00203801 |
| Malaria Elimination Pilot Study in Military Forces in Cambodia |
Active, not recruiting |
Malaria|Parasitic Diseases |
NCT02653898 |
| Mass-Drug Administration to Reduce Malaria Transmission |
Completed |
Malaria, Falciparum |
NCT00509015 |
| Antimalarial Treatments for Clearing Low Density P. Falciparum and Its Impact on Malaria Transmission |
Completed |
Plasmodium Falciparum|Asymptomatic Parataemia|Sub Patent Parasitaemia |
NCT00646126 |
| The Synergistic Effects of Home-management and Intermittent Preventive Treatment of Malaria in Children |
Completed |
Malaria |
NCT00550160 |
| A Trial of Four Drug Regimens for the Prevention of Malaria in Senegalese Children |
Completed |
Malaria |
NCT00132548 |
| Safety of Artemether - Lumefantrine, and Other Malaria Drugs and Their Effect on the Auditory Function |
Terminated |
Malaria|Falciparum |
NCT00386750 |
| Intermittent Preventive Treatment (IPTp) Versus Rapid Diagnostic Testing (RDT) and Treatment of Malaria in Pregnancy |
Completed |
Malaria|Anaemia|Pregnancy |
NCT00432367 |
| A Comparative Study of Artekin With Standard Malarial Treatment Regimes in Afghanistan |
Completed |
Uncomplicated Falciparum Malaria|Vivax Malaria |
NCT00682578 |
| A Study by the Tracking Resistance to Artemisinin Collaboration (TRAC) |
Completed |
Malaria, Falciparum |
NCT02453308 |
| Relationship Between HIV and Malaria in Ugandan Children |
Completed |
HIV Infections|Malaria |
NCT00356824 |
| Antimalaria Drugs Susceptibility Testing for an Effective Management of Infected Patients in Sub-Sahara Africa |
Completed |
Drug Resistant Malaria Due to Plasmodium Falciparum |
NCT02974348 |
| Novel Agents for Treatment of High-risk COVID-19 Positive Patients |
Recruiting |
COVID|Sars-CoV2 |
NCT04374019 |
| A Study to Assess Current Standard Malaria Treatment Guidelines in the Republic of the Sudan |
Completed |
Malaria |
NCT02592408 |
| Restricting the Use of Artesunate Plus Amodiaquine Combination Therapy to Malaria Cases Confirmed by a Dipstick Test: A Cluster Randomised Control Trial |
Completed |
Malaria |
NCT00832754 |
| A Trial of Antimalarial Drugs Used in Pregnancy in Tanzania |
Completed |
Malaria |
NCT00146731 |
| Safety and Immunogenicity of Sanaria's Irradiated Sporozoite Vaccine (PfSPZ Vaccine) in Malaria-Experienced Adults in Burkina Faso |
Completed |
Plasmodium Falciparum Infection |
NCT02663700 |
| COVID-19 Treatment in South Africa |
Completed |
COVID-19 |
NCT04532931 |
| Effect of Paracetamol on Renal Function in Plasmodium Knowlesi Malaria |
Completed |
Malaria |
NCT03056391 |
| Mefloquine Bioequivalence Among 3 Commercially Available Tablets. |
Completed |
Malaria |
NCT00544024 |
| Effect of Artemisinin-based Combination Therapies on Schistosomiasis on Malaria Co-infection |
Completed |
Schistosomiasis Haematobia |
NCT04264130 |
| Effectiveness of Artemisinin Combination Regimens in Falciparum Malaria |
Unknown status |
Uncomplicated Falciparum Malaria |
NCT00902811 |
| Safety and Efficacy of Sanaria's PfSPZ-CVac in Malian Adults |
Completed |
Plasmodium Falciparum Infection |
NCT02996695 |
| Longitudinal Antimalarial Combinations in Uganda |
Completed |
Malaria |
NCT00123552 |
| Safety and Preliminary Efficacy of L-arginine in Severe Falciparum Malaria |
Suspended |
Severe Falciparum Malaria |
NCT00616304 |
| Azithromycin Combination Therapy for Malaria |
Completed |
Plasmodium Falciparum Malaria |
NCT00299208 |
| Intermittent Preventive Treatment With Antimalarials in Kenyan Infants |
Completed |
Malaria|Anemia |
NCT00111163 |
| Antimalarial Drug Resistance in Mali |
Completed |
Malaria |
NCT00127998 |
| Antioxidant Micronutrients in Malaria |
Completed |
Malaria |
NCT01152931 |
| Examination of Protective Factors Against Severe Malaria |
Completed |
Malaria|Severe Malaria |
NCT00342043 |
| The Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients (Phase3) |
Recruiting |
COVID-19 |
NCT05084911 |
| Monitoring of Molecular Markers of Artemisinin Resistance Through Repeated Cross-sectional Assessments in DR Congo, Nigeria and Uganda |
Completed |
Severe Malaria |
NCT04037332 |
| Clinical Study to Assess Efficacy and Safety of Amiodarone in Treating Patients With Ebola. Virus Disease (EVD) in Sierra Leone. EASE (EMERGENCY Amiodarone Study Against Ebola) |
Withdrawn |
Ebola Virus Disease |
NCT02307591 |
| P. Knowlesi Trial of Artemether-lumefantrine vs Chloroquine |
Completed |
Uncomplicated Knowlesi Malaria |
NCT02001012 |
| Artemether-lumefantrine vs Chloroquine for Uncomplicated P. Vivax Malaria in Malaysia |
Unknown status |
Plasmodium Vivax Malaria Without Complication |
NCT02348788 |
| Malaria Survey in the Tak Province Refugee Camps |
Completed |
Malaria |
NCT01902797 |
| Comparison Between 7 and 14 Day Primaquine Combined With Dihydroartemisinin-piperaquine or 3 Day Chloroquine Radical Cure of P. Vivax (BPD) |
Completed |
Vivax Malaria |
NCT01640574 |
| Human Mass Balance Study of Pyronaridine |
Completed |
Malaria |
NCT01383109 |
| Severe Malaria and Anti-malarial Drug Resistance in Cambodia |
Completed |
Severe Malaria|Malaria|Antimalarial Drug Resistance |
NCT00341003 |
| A Healthy Volunteer Safety Study of Pyronaridine Tetraphosphate Taken in Combination With Piperaquine Tetraphosphate |
Not yet recruiting |
Healthy |
NCT05160363 |
| Baseline Cohort Malaria Morbidity Study |
Recruiting |
Malaria |
NCT04601714 |
| Post-discharge Malaria Chemoprevention(PMC) Study |
Completed |
Malaria|Severe Anemia |
NCT02671175 |
| Innate and Acquired Resistance to Plasmodium Falciparum Malaria in Mali |
Completed |
Malaria |
NCT00669084 |
| Efficacy And Safety Of AL For The Treatment Of Uncomplicated Falciparum Malaria In Mainland Tanzania |
Completed |
Uncomplicated Malaria |
NCT03387631 |
| Malaria Studies in Cambodia |
Completed |
Malaria |
NCT00663546 |
| Pharmacokinetic and in Vitro Transmission Blocking Activities Study of Primaquine Compare to Methylene Blue in Healthy Volunteer Both G6PD Normal and G6PD Deficiency |
Completed |
G6PD Normal|G6PD Deficient|Healthy |
NCT01668433 |
| Evaluation of the Public Health Impact of Seasonal Intermittent Preventive Treatment (IPT) in Children in Senegal |
Unknown status |
Malaria |
NCT00712374 |
| Plasmodium Immunotherapy for Lung Cancer |
Unknown status |
Lung Cancer, Nonsmall Cell |
NCT02786589 |
| Assessing the Effect of Strengthening Referral of Sick Children From the Private Health Sector and Its Impact on Referral Uptake in Uganda. |
Unknown status |
Malaria |
NCT02450630 |
| Targeting High Risk Populations With Enhanced Reactive Focal Mass Drug Administration in Thailand |
Recruiting |
Plasmodium Falciparum Malaria|Plasmodium Vivax Malaria |
NCT05052502 |
| Treating Brain Swelling in Pediatric Cerebral Malaria |
Recruiting |
Malaria, Cerebral |
NCT03300648 |
| Biomarkers of P. Vivax Relapse |
Recruiting |
Malaria|Vivax Malaria|Relapse|CYP2D6 Polymorphism |
NCT04228315 |
| Add on to Azythromycine, Phytomedicine and/or Antimalarial Drug vs Hydroxychloroquine in Uncomplicated COVID-19 Patients |
Enrolling by invitation |
Covid19 |
NCT04502342 |
| Assessment of Use of Rapid Diagnostic Testing in the Context of Home Management With ACTs |
Completed |
Malaria|Pneumonia |
NCT00720811 |
| Dose Escalation PfSPZ-CVac |
Completed |
Malaria |
NCT03083847 |
| Feasibility, Acceptability and Costs of a Multiple First-lines Artemisinin-based Combination Therapies |
Recruiting |
Malaria |
NCT04265573 |
| Cluster Randomised Trial of Malaria RDTs Used by CHWs in Afghanistan |
Completed |
Malaria|Fever|Acute Febrile Illness|Pneumonia |
NCT01403350 |
| Pathophysiological Explorations of Red Blood Cells |
Recruiting |
Red Blood Cell Disorder |
NCT03541525 |
| Safety, Immunogenicity, and Protective Efficacy of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites in Healthy African Adults in Mali |
Completed |
Malaria |
NCT02627456 |
| Rosiglitazone Adjunctive Therapy for Severe Malaria in Children |
Active, not recruiting |
Malaria |
NCT02694874 |
